Results 21 to 30 of about 8,147 (216)

Carboplatin Hyperthermic Intraperitoneal Chemotherapy (HIPEC) Is Safe and Efficacious in Recurrent and Advanced Ovarian Cancer

Graduate Medical Education Research Journal, 2020
Mentor: Jason Foster Program: General Surgery Type: Original Research Background: HIPEC with cisplatin in recurrent and advanced ovarian cancer (AOC) improves survival, but renal toxicity is common, even with renal protectants.
Chunmeng Zhang, Ryan Mikus, Dalton Hegeholz, Valerie Shostrom, Abraham Matthews, James Commers, Laura Lambert, Jason Foster   +7 more
doaj   +1 more source

HIPEC-Induced Acute Kidney Injury: A Retrospective Clinical Study and Preclinical Model [PDF]

, 2021
Background!#!Hyperthermic intraperitoneal chemotherapy (HIPEC) combined with cytoreductive surgery (CRS) is the treatment of choice for selected patients with peritoneal malignancies.
Eckert, Christoph, Brune, Maik, Hillebrecht, H. Christian, Schneider, Martin, Wagner, Benedikt, Schmidt, Thomas, Liesenfeld, Lukas F., Klose, Johannes, Büchler, Markus W.   +8 more
core   +1 more source

Interval debulking surgery with or without hyperthermic intraperitoneal chemotherapy in advanced-stage ovarian cancer: Single-institution cohort study

Frontiers in Oncology, 2022
To evaluate the additive effects of hyperthermic intraperitoneal chemotherapy (HIPEC) to interval debulking surgery (IDS) in patients with advanced-stage ovarian cancer.
Yong Jae Lee, Ki Eun Seon, Dae Chul Jung, Jung-Yun Lee, Eun Ji Nam, Sang Wun Kim, Sunghoon Kim, Young Tae Kim   +7 more
doaj   +1 more source

PIPAC – Pressurized Intraperitoneal Aerosole Chemotherapy, HIPEC oder PIPAC? [PDF]

, 2021
Eine lokale, intraperitoneale Verabreichung von Chemotherapeutika ist ein naheliegendes Therapiekonzept des Ovarialkarzinomes, welches in der Mehrzahl der Patientinnen in einem fortgeschrittenen, peritoneal metastasierten Stadium (FIGO III/IV ...
Saner, Flurina, Mueller, Michael D.
core  

Hyperthermic intraperitoneal chemotherapy (HIPEC) after primary debulking surgery in advanced epithelial ovarian cancer: Is BRCA mutational status making the difference?

Cancer Treatment and Research Communications, 2022
Introduction: The role of a molecular pattern predictive of hyperthermic intraperitoneal chemotherapy (HIPEC) efficacy in advanced ovarian cancer (AOC) patients has been poorly investigated.
Valentina Ghirardi, Francesca De Felice, Marco D'Indinosante, Federica Bernardini, Maria Teresa Giudice, Anna Fagotti, Giovanni Scambia   +6 more
doaj   +1 more source

Modeling of Chemoperfusion vs. Intravenous Administration of Cisplatin in Wistar Rats: Adsorption and Tissue Distribution

Molecules, 2020
Hyperthermic intraperitoneal chemoperfusion (HIPEC) is an established form of locoregional chemotherapy of peritoneum tumors. However, its efficacy and safety status remain a controversy, partially, due to scarce data on pharmacokinetics and toxicity ...
Galina Kireeva, Stepan Kruglov, Mikhail Maydin, Ekaterina Gubareva, Elena Fedoros, Ekaterina Zubakina, Natalya Ivanenko, Marina Bezruchko, Nikolay Solovyev   +8 more
doaj   +1 more source

The efficacy of traditional chinese medicine combined with hyperthermic intraperitoneal chemotherapy for malignant ascites: A systematic review and meta-analysis

Frontiers in Pharmacology, 2022
Objective: Malignant ascites (MA) is a common complication of terminal cancer, which seriously affects the life quality and prognosis of patients. Both hyperthermic intraperitoneal chemotherapy (HIPEC) and traditional Chinese medicine (TCM) preparations ...
Zhixian Lin, Jiangfeng Chen, Yunxia Liu
doaj   +1 more source

The impact of HIPEC vs. EPIC for the treatment of mucinous appendiceal carcinoma: a study from the US HIPEC collaborative [PDF]

, 2020
Introduction Mucinous appendiceal carcinoma is a rare malignancy that commonly spreads to the peritoneum leading to peritoneal metastases. Complete cytoreduction with perioperative intraperitoneal chemotherapy (PIC) is the mainstay of treatment ...
Mustafa Raoof, Courtney Pokrzywa, Mohammad Y. Zaidi, Harveshp Mogal, Oliver Eng, Jula Veerapongh, Laura A. Lambert, Fabian M. Johnston, Courtney N. Day, Ryan J. Hendrix, Sameer H. Patel, Sophie Dessureault, Jennifer L. Leiting, Mackenzie C. Morris, Andrew J. Lee, Sherif Abdel-Misih, Joel M. Baumgartner, Travis E. Grotz, Keith Fournier, Jordan M. Cloyd, Callisia Clarke, William S. Harmsen, Maria C. Russell, Jonathan Greer, Sean Dineen, Daniel E. Abbott   +25 more
core   +1 more source

The Global End-Diastolic Volume (GEDV) Could Be More Appropiate to Fluid Management Than Central Venous Pressure (CVP) During Closed Hyperthermic Intrabdominal Chemotherapy with CO2 Circulation

Journal of Investigative Surgery, 2018
Background: Closed hyperthermic intraperitoneal chemotherapy (HIPEC) may increase abdominal pressure and effects of hemodynamic changes due to maintenance hyperthermia.
Francisco Javier Redondo, David Padilla, Pedro Villarejo, Victor Baladron, Patricia Faba, Sergio Sánchez, José Ramón Muñoz-Rodríguez, Natalia Bejarano   +7 more
doaj   +1 more source

The prognosis impact of hyperthermic intraperitoneal chemotherapy (HIPEC) plus cytoreductive surgery (CRS) in advanced ovarian cancer: the meta-analysis

Journal of Ovarian Research, 2019
Background and objective Previous studies about the prognostic value of the HIPEC have yielded controversial results. Therefore, this study aims to assess the impact of HIPEC on patients with ovarian cancer.
Guyu Zhang, Yimin Zhu, Chongdong Liu, Guangming Chao, Ran Cui, Zhenyu Zhang   +5 more
doaj   +1 more source