Results 51 to 60 of about 9,325 (168)

Cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) vs CRS alone for treatment of endometrial cancer with peritoneal metastases: a multi-institutional study from PSOGI and BIG RENAPE groups

BMC Surgery, 2022
Objective To investigate the benefit of cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) for the treatment of endometrial peritoneal carcinomatosis compared to CRS alone.
Manuel Gomes David, Naoual Bakrin, Julia Salleron, Marie Christine Kaminsky, Jean Marc Bereder, Jean Jacques Tuech, Kuno Lehmann, Sanket Mehta, Olivier Glehen, Frédéric Marchal   +9 more
doaj   +1 more source

Single‐Cell Transcriptomic Analysis of Tumor Heterogeneity and the Microenvironment in Pseudomyxoma Peritonei

Advanced Science, Volume 13, Issue 58, 19 October 2026.
This study presents a single‐cell atlas of pseudomyxoma peritonei spanning primary and paired metastatic lesions. Distinct epithelial substates, stromal remodeling, immune exclusion, lipid metabolic reprogramming, and a candidate angiogenic network were identified in metastatic lesions.
Xi Li, Lei Wang, Lei Ai, Zimeng Li, Zhaochangci Chen, Yuchen Luo, Tianran Zhang, Mengjia Liao, Songhao Wang, Jiajia Cui, Ke Liu, Chengxian Guo, Guodong Liu, Jiye Yin, Wei Wu   +14 more
wiley   +1 more source

Perioperatives Management im Rahmen der CRS und HIPEC

, 2018
Cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC) are therapeutic options for the treatment of intra-abdominal neoplasms.
Sinner, B., Bleiler, S., Bleiler, D.
core   +1 more source

The impact of HIPEC vs. EPIC for the treatment of mucinous appendiceal carcinoma: a study from the US HIPEC collaborative

, 2020
Introduction Mucinous appendiceal carcinoma is a rare malignancy that commonly spreads to the peritoneum leading to peritoneal metastases. Complete cytoreduction with perioperative intraperitoneal chemotherapy (PIC) is the mainstay of treatment ...
Mustafa Raoof, Courtney Pokrzywa, Mohammad Y. Zaidi, Harveshp Mogal, Oliver Eng, Jula Veerapongh, Laura A. Lambert, Fabian M. Johnston, Courtney N. Day, Ryan J. Hendrix, Sameer H. Patel, Sophie Dessureault, Jennifer L. Leiting, Mackenzie C. Morris, Andrew J. Lee, Sherif Abdel-Misih, Joel M. Baumgartner, Travis E. Grotz, Keith Fournier, Jordan M. Cloyd, Callisia Clarke, William S. Harmsen, Maria C. Russell, Jonathan Greer, Sean Dineen, Daniel E. Abbott   +25 more
core   +1 more source

Peripheral Lymphocyte Subsets Predict Efficacy and Overall Survival in Gastric Cancer Patients Receiving Preoperative Chemotherapy: A Retrospective Cohort Study

Cancer Reports, Volume 9, Issue 10, October 2026.
ABSTRACT Background Pathologic complete response (pCR), which reflects the local immune status and preoperative chemotherapy efficacy, has garnered significant attention in gastric cancer research. However, the predictive value of peripheral lymphocyte subsets for pCR in gastric cancer patients receiving preoperative chemotherapy remains unclear.
Zirui Xue, Dan Liu, Zhaodong Sun, Bosen Li, Xinyou Liu, Junjie Zhao, Haojie Li, Xuefei Wang, Zhaoming Wang   +8 more
wiley   +1 more source

MODERN STRATEGY IN TREATMENT OF PERITONEAL CARCINOMATOSIS

Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2017
Peritoneal carcinomatosis (PC) is a common manifestation of progression in peritoneal and gynecologic malignancies. Current primary strategy in treatment of PC is the concept of regional influence by the way of cytoreductive surgery and intraperitoneal ...
A. A. Zakharenko, D. A. Zaitcev, M. A. Belyaev, A. A. Trushin, O. A. Ten, A. S. Natkha, K. N. Vovin, V. A. Rybalchenko   +7 more
doaj   +1 more source

Trophoblast Extracellular Vesicles Rewire Immunity: A Symptom‐Relief Avenue for Recessive Dystrophic Epidermolysis Bullosa

Journal of Extracellular Vesicles, Volume 15, Issue 10, October 2026.
First‐trimester trophoblast EVs are enriched in anti‐inflammatory proteins, lipids, and immunoregulatory miRNAs. EVT‐EVs reprogram monocytes toward a pro‐resolving phenotype and restore immune homeostasis in RDEB, supporting their potential as offering a scalable off‐the‐shelf therapy for chronic inflammatory diseases.
Nell Hirt, Enzo Manchon, Ming Wu, Helene Le Buanec, Pauline Bataille, Emmanuelle Bourrat, Jean‐David Bouaziz, Nabila Jabrane‐Ferrat, Reem Al‐Daccak   +8 more
wiley   +1 more source

Colorectal Cancer: Epidemiology, Risk Factors, Signaling Pathways, Clinical Features, Screening, Diagnosis, and Management

MedComm, Volume 7, Issue 10, October 2026.
Colorectal cancer is a heterogeneous, adaptive disease shaped by population‐level risk, genomic and epigenetic alterations, tumor ecosystem evolution, and treatment pressure. This review integrates epidemiology, risk factors, signaling networks, clinical presentation, screening, molecular diagnosis, and stage‐ and biomarker‐guided management while ...
Kairui Wan, Ke Tang, Linglong Wang, Qin Tian, Mingwei Zheng, Cheng Qian, Limei Liu   +6 more
wiley   +1 more source

Hyperthermic intraperitoneal chemotherapy: Ideal and reality

Asian Journal of Surgery
Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) is a new adjuvant therapy for the treatment of abdominal malignant tumors and metastases, which has shown great potential.
Fan-He Dong, Yu-Qiang Shan, Wen-Cheng Kong, Hao-Ran Wei, Lin-Po Zhou, Ye-Bin Yang, Jing Shi, Cheng-Hao Ji, Yi-Jia Zhang   +8 more
doaj   +1 more source

Meta‐analysis of prognostic factors for patients with colorectal peritoneal metastasis undergoing cytoreductive surgery and heated intraperitoneal chemotherapy

BJS Open, 2019
Background Up to 15 per cent of colorectal cancers present with peritoneal metastases (CPM). Cytoreductive surgery and heated intraperitoneal chemotherapy (CRS + HIPEC) aims to achieve macroscopic tumour resection combined with HIPEC to destroy ...
S. Hallam, R. Tyler, M. Price, A. Beggs, H. Youssef   +4 more
doaj   +1 more source