Results 61 to 70 of about 8,980 (210)

Efficacy and safety of hyperthermic intraperitoneal intraoperative chemotherapy plus surgery in advanced ovarian cancer patients

Journal of International Medical Research
Objective This study aimed to evaluate the efficacy and safety of hyperthermic intraperitoneal intraoperative chemotherapy (HIPEC) in patients with advanced ovarian cancer.
Chang Yanan, Liu Ting, Cao Wei Li, Xu Yaxin, Chen Hong   +4 more
doaj   +1 more source

Spatiotemporal immune heterogeneity and precision immunotherapy for ovarian cancer

Clinical and Translational Medicine, Volume 16, Issue 9, September 2026.
Graphical Highlights Spatiotemporal immune heterogeneity shapes distinct and evolving immune ecosystems in ovarian cancer. Multimodal biomarkers enable biologically informed patient stratification beyond static single‐marker approaches. Precision immunotherapy should match dominant immune barriers across lesions and treatment stages.
Xinfeng Yang, Yida Wang, Haiyue You, Jingyi Gao, Yangkun Feng, Feng Zhang, Yan Zhang, Bing Zhang, Shaojie Zhao, Yanfang Gu   +9 more
wiley   +1 more source

Cytoreductive surgery (CRS) plus hyperthermic intraperitoneal chemotherapy (HIPEC) vs CRS alone for treatment of endometrial cancer with peritoneal metastases: a multi-institutional study from PSOGI and BIG RENAPE groups

BMC Surgery, 2022
Objective To investigate the benefit of cytoreductive surgery (CRS) combined with hyperthermic intraperitoneal chemotherapy (HIPEC) for the treatment of endometrial peritoneal carcinomatosis compared to CRS alone.
Manuel Gomes David, Naoual Bakrin, Julia Salleron, Marie Christine Kaminsky, Jean Marc Bereder, Jean Jacques Tuech, Kuno Lehmann, Sanket Mehta, Olivier Glehen, Frédéric Marchal   +9 more
doaj   +1 more source

Therapeutic Applications of Stimuli‐Based Release and Engineering of Extracellular Vesicles

Advanced NanoBiomed Research, Volume 6, Issue 8, August 2026.
This review summarizes the effects of endogenous and exogenous stimuli, their effects on the natural release of extracellular vesicles, as well as their uptake and release. It also gives an overview of stimuli‐responsive EVs and their therapeutic applications. Extracellular vesicles (EVs), nano‐ to microsized lipid bilayer membrane‐bound particles, are
Gloria Kemunto, Kristen Dellinger
wiley   +1 more source

An Open Source Automated Tumor Infiltrating Lymphocytes Algorithm for Prognosis in Primary Small Bowel Adenocarcinoma Using Routine Hematoxylin and Eosin Stained Sections

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Objective While tumor‐infiltrating lymphocytes (TILs) are prognostic in various cancers, their role in small bowel adenocarcinoma (SBA) is unexplored. This study evaluates the prognostic significance of digitally quantified TILs in SBA. Methods Using digital pathology (QuPath) on hematoxylin and eosin (H&E)‐stained slides from 62 SBA cases, we
Minying Deng, Xin Liu, Yuanlong Luo, Ayizimugu Abuduwaili, Qi Song, Rongkui Luo, Wen Huang, Lei Xu, Xiaolei Zhang, Lin Sun, Jieakesu Su, Chen Xu, Yingyong Hou   +12 more
wiley   +1 more source

Hyperthermic intraperitoneal chemotherapy: Ideal and reality

Asian Journal of Surgery
Hyperthermic Intraperitoneal Chemoperfusion (HIPEC) is a new adjuvant therapy for the treatment of abdominal malignant tumors and metastases, which has shown great potential.
Fan-He Dong, Yu-Qiang Shan, Wen-Cheng Kong, Hao-Ran Wei, Lin-Po Zhou, Ye-Bin Yang, Jing Shi, Cheng-Hao Ji, Yi-Jia Zhang   +8 more
doaj   +1 more source

MODERN STRATEGY IN TREATMENT OF PERITONEAL CARCINOMATOSIS

Учёные записки Санкт-Петербургского государственного медицинского университета им. Акад. И.П. Павлова, 2017
Peritoneal carcinomatosis (PC) is a common manifestation of progression in peritoneal and gynecologic malignancies. Current primary strategy in treatment of PC is the concept of regional influence by the way of cytoreductive surgery and intraperitoneal ...
A. A. Zakharenko, D. A. Zaitcev, M. A. Belyaev, A. A. Trushin, O. A. Ten, A. S. Natkha, K. N. Vovin, V. A. Rybalchenko   +7 more
doaj   +1 more source

Current Advances of Molecular Biomarkers and Liquid Biopsies Techniques in Ovarian Cancer

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Ovarian cancer (OC) remains a lethal gynecological malignancy with challenges in early diagnosis, treatment monitoring, and overcoming drug resistance. Liquid biopsy, a noninvasive approach analyzing tumor‐derived components in bodily fluids, has emerged as a promising tool in OC management.
Jingxia Zhang, Weiyan Shan, Jie Yu, Huan Shi, Qiaoping Xu, Hongkai Shang   +5 more
wiley   +1 more source

Overall survival post secondary cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for recurrent colorectal cancer with peritoneal metastases

World Journal of Surgical Oncology
Background Colorectal cancer is the third-most common malignancy worldwide. It has the potential to develop peritoneal metastases (CRPM), which can be treated using cytoreductive surgery (CRS) and hyperthermic intraperitoneal chemotherapy (HIPEC).
Raymond Hayler, Celine Garrett, Jessica Guo, Shoma Barat, Mina Sarofim, Ruwanthi Wijayawardana, Nima Ahmadi, Winston Liauw, David L. Morris   +8 more
doaj   +1 more source

Effects of Prehabilitation by Physical Activity on Fatigue After Surgery for Colorectal Cancer. Results From Secondary Analyses in the Randomized Controlled Trial PHYSSURG‐C

Cancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Objective The objective of this study is to explore effects on self‐reported fatigue at 4 weeks and 12 months after surgery in patients with colorectal cancer undergoing a pre‐ and postoperative exercise intervention compared to standard care in a randomized trial.
Kevin Afshari, Aron Onerup, Ying Li, Eva Angenete, Carolina Ehrencrona, Anette Wedin, Eva Haglind   +6 more
wiley   +1 more source