Results 81 to 90 of about 8,980 (210)

Delivering Proteins and Enzymes to Solid Tumors Through the Development of Stimuli‐Responsive Nanocarriers

ChemNanoMat, Volume 12, Issue 6, June 2026.
Stimuli‐responsive strategies to achieve controlled release of protein‐based therapeutic agents into solid tumors. Proteins, enzymes, and peptides have long been recognized as valuable therapeutic agents, particularly in oncology. However, their complex chemical structures render them more sensitive than smaller chemotherapeutic drugs.
Guillermo Plaza‐Palomo, Diana Benita‐Donadios, Sandra Jiménez‐Falcao, Alejandro Baeza   +3 more
wiley   +1 more source

Prophylactic HIPEC with radical D2 gastrectomy improves survival and peritoneal recurrence rates for locally advanced gastric cancer: personal experience from a randomized case control study

BMC Cancer, 2019
Background To investigate the implications of prophylactic intraoperative Hyperthermic Intraperitoneal Chemotherapy (HIPEC) with D2 radical gastrectomy for locally advanced Gastric Cancer (AGC) in a randomized case control study.
Maneesh Kumarsing Beeharry, Zheng-Lun Zhu, Wen-Tao Liu, Xue-Xin Yao, Min Yan, Zheng-Gang Zhu   +5 more
doaj   +1 more source

Effect of HIPEC on thrombin generation.

, 2018
Effect of HIPEC on thrombin generation.
Abraham Marcus (5435150), Seppe Dehaene (5435153), Kurt Van der Speeten (5435147), Joris Penders (4163893), Sven Van Poucke (843417), Dana Huskens (211452), Ming-Hua Zheng (138448), Marcus Lancé (4916833), Bart Lauwereins (5435156), Mark Roest (377867)   +9 more
core   +1 more source

HIPEC in advanced epithelial ovarian cancer: why is there controversy?

, 2020
: Purpose of review The randomized OVHIPEC study provided further evidence that adding heated intraperitoneal chemotherapy (HIPEC) to interval cytoreductive surgery significantly improved recurrence-free and overall survival in stage III epithelial ...
Brand, Alison, Van Dam, Peter Andr\ue9, Jan B. Vermorken, Vermorken, Jan Baptist, Peter van Dam, Alison Brand   +5 more
core   +1 more source

Feasibility study of chemotherapeutic efficacy assessment in hyperthermic intraperitoneal chemotherapy (HIPEC)

Discover Medicine
Purpose CRS-HIPEC serves as the primary treatment for peritoneal cancers. Although CRS-HIPEC frequently yields positive outcomes, some patients may experience a swift recurrence of cancer.
Ahmed H. Mekkawy, Md Khalilur Rahman, Mohammad Breakeit, Krishna Pillai, Samina Badar, Javed Akhter, Michelle Dietz, Shoma Barat, Sarah J. Valle, David L. Morris   +9 more
doaj   +1 more source

Effect of HIPEC on platelet function.

, 2018
Effect of HIPEC on platelet function.
Abraham Marcus (5435150), Seppe Dehaene (5435153), Kurt Van der Speeten (5435147), Joris Penders (4163893), Sven Van Poucke (843417), Dana Huskens (211452), Ming-Hua Zheng (138448), Marcus Lancé (4916833), Bart Lauwereins (5435156), Mark Roest (377867)   +9 more
core   +1 more source

Cytoreductuctive surgery and HIPEC

, 2017
Systemic treatment alone is no longer appropriate for patients with limited peritoneal dissemination from primary or recurrent colon cancer. A clinical pathway for the management of these patients should include cytoreductive surgery and HIPEC. There are four specific problems that have to be resolved in the future in order to improve survival of the ...
Kekez, Tihomir, Kinda, Emil, Jelinčić, Željko, Majerović, Mate, Golem, Ante Zvonimir, Silovski Hrvoje, Augustin, Goran, Matošević, Petar, Bruketa, Tomislav, Bogdanić, Branko, Majsec Budak, Ana   +10 more
openaire   +3 more sources

An acute cardiac complication of HIPEC [PDF]

Asian Journal of Oncology, 2016
Recently, cytoreductive surgery (CRS) followed by hyperthermic intraperitoneal chemotherapy (HIPEC) has been described for both treatment and prevention of locoregional cancer of various origin. As this procedure involves large amount of blood and fluid loss during the CRS phase, and haemodynamic, metabolic, and coagulation changes during the HIPEC ...
openaire   +1 more source

HIPEC application potential in the treatment of extensive carcinomatosis in ovarian cancer (retrospective study)

Acta Biomedica Scientifica
Background. The high prevalence of advanced forms of cancer currently requires new treatment approaches. Only modern high-tech surgical procedures can provide means for improving the results of treatment.The aim.
S. I. Radostev, L. A. Kolomiets, A. V. Shelekhov, R. A. Zubkov, D. D. Morikov, А. A. Medvednikov   +5 more
doaj   +1 more source

Minimally Invasive Secondary Cytoreduction Plus HIPEC Versus Open Surgery Plus HIPEC in Isolated Relapse From Ovarian Cancer: A Retrospective Cohort Study on Perioperative Outcomes

, 2015
STUDY OBJECTIVE: To compare the perioperative outcomes of minimally invasive secondary cytoreduction surgery (SCS) plus hyperthermic intraoperative intraperitoneal chemotherapy (HIPEC) versus open surgery plus HIPEC in a group of platinum-sensitive ...
Fagotti, A, Scambia, Giovanni, Fanfani, F.   +2 more
core   +2 more sources