Results 111 to 120 of about 114,310 (305)
Redeeming Rhetoric: Augustine\u27s Use of Rhetoric in His Preaching Ministry [PDF]
, 2015 The art and practice of rhetoric occupied a fundamental place in the ancient Roman world. It is thus not surprising that Augustine (354-430 AD) was deeply committed to the art of speaking well. He spent his youth mastering the theory of rhetoric, putting
Sypert, John A
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Advanced Science, EarlyView.Zmat1 deficiency mitigates pathological bone loss by impairing osteoclastogenesis and promoting osteoblastogenesis. Mechanistically, in osteoclasts, Zmat1 loss relieves transcriptional repression of the E3 ligase TRIM46, promoting YAP1 degradation and inhibiting osteoclastogenic genes.
Xinyu Chang +13 more
wiley +1 more source
Age-Dependent Changes in Transcription Factor FOXO Targeting in Female Drosophila
Frontiers in Genetics, 2019 FOXO transcription factors have long been associated with longevity control and tissue homeostasis. Although the transcriptional regulation of FOXO have been previously characterized (especially in long-lived insulin mutants and under stress conditions),
Allison Birnbaum +5 more
doaj +1 more source
Advanced Science, EarlyView.Gastric cancer‐derived exosomal TAGLN2 is identified as a key mediator of vascular reprogramming, with significantly elevated levels detected in patient serum. Independent of canonical SEMA4D signaling, it nucleates a cytoplasmic TAGLN2/NRP1/SEMA4D ternary complex that dually activates YAP, promoting angiogenesis, vascular dysfunction, and metastasis ...
Shuqi Yu +7 more
wiley +1 more source
Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution
Advanced Science, EarlyView.Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley +1 more source
Advanced Science, EarlyView.This study utilizes programmable mechanical pressure as a therapeutic enhancer to establish a mechano‐chemotherapy strategy. Controlled pressure activates the mechanosensitive ion channel Piezo1 in bladder cancer, triggering a calcium ion cascade that transiently and reversibly amplifies membrane permeability to chemotherapeutics.
Minghai Ma +16 more
wiley +1 more source
A Meta-Analysis of Alternative Water Sources [PDF]
, 2012 Roughly one half of the Earth’s population suffers from shortage or lack of clean water. While many innovations and products have been created to address this Global Water Crisis, no comparisons have been done as to which innovations and products are the
Colton, Katie
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FGL2‐HDAC11 Drives Immunothrombosis via NETs‐Mediated Endothelial Capillarization in MASLD Fibrosis
Advanced Science, EarlyView.ABSTRACT Metabolic dysfunction–associated steatotic liver disease (MASLD) is frequently accompanied by hepatic fibrosis and systemic cardiovascular complications; however, the mechanistic interplay between coagulation abnormalities and disease progression remains poorly defined.
Xitang Li +16 more
wiley +1 more source
Inhibition of chemotherapy resistant breast cancer stem cells by a ROR1 specific antibody. [PDF]
, 2019 Breast cancers enduring treatment with chemotherapy may be enriched for cancer stem cells or tumor-initiating cells, which have an enhanced capacity for self-renewal, tumor initiation, and/or metastasis.
Carson, Dennis A +17 more
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Hippo Pathway in Cancer, towards the Realization of Hippo-Targeted Therapy [PDF]
Cancers, 2018 n ...
openaire +2 more sources