Results 11 to 20 of about 56,542 (314)

p53 shades of Hippo [PDF]

open access: yesCell Death & Differentiation, 2017
The three p53 family members, p53, p63 and p73, are structurally similar and share many biochemical activities. Yet, along with their common fundamental role in protecting genomic fidelity, each has acquired distinct functions related to diverse cell autonomous and non-autonomous processes. Similar to the p53 family, the Hippo signaling pathway impacts
Noa, Furth, Yael, Aylon, Moshe, Oren
openaire   +2 more sources

Cutting-Edge Technologies for Digital Therapeutics: A Review and Architecture Proposals for Future Directions

open access: yesApplied Sciences, 2023
Digital therapeutics, evidence-based treatments delivered through software programs, are revolutionizing healthcare by utilizing cutting-edge computing technologies.
Joo Hun Yoo   +2 more
doaj   +1 more source

Activating transcription factor 6 promotes proliferation, migration and invasion of PC3 human prostate cancer cells through Hippo-YAP signaling pathway

open access: yes陆军军医大学学报, 2023
Objective To investigate the effects of activating transcription factor 6 (ATF6) on the proliferation, migration and invasion of prostate cancer PC3 cells.
LIU Hengchuan   +5 more
doaj   +1 more source

Hippo Enters the Competition [PDF]

open access: yesDevelopmental Cell, 2019
In this issue of Developmental Cell, Hashimoto and Sasaki (2019) explore the role of the Hippo pathway in the establishment of naive pluripotency and cell competition in the epiblast. Their work gives insight into how the mouse embryo selects cells with the highest future potential, through the activity of YAP/TEAD.
Christophe, Royer, Shankar, Srinivas
openaire   +2 more sources

LECTURERS’ STRATEGIES ON STUDENTS' DISCIPLINE IN CLASSROOM MANAGEMENT DURING ONLINE LEARNING [PDF]

open access: yes, 2023
This study aims to provide an overview of the strategies used by two lecturers at the Catholic University of St. Augustine Hippo in their online classroom management, particularly in disciplining students. The trend of online classes on the St. Augustine
Purnomo, Kristian Anggi   +3 more
core   +1 more source

Willin, an upstream component of the Hippo signaling pathway, orchestrates mammalian peripheral nerve fibroblasts [PDF]

open access: yes, 2013
Willin/FRMD6 was first identified in the rat sciatic nerve, which is composed of neurons, Schwann cells, and fibroblasts. Willin is an upstream component of the Hippo signaling pathway, which results in the inactivation of the transcriptional coactivator
Tilston-Lünel, A.M.   +45 more
core   +1 more source

Hippo signaling at a glance [PDF]

open access: yesJournal of Cell Science, 2010
How the organs of multicellular organisms develop to a pre-defined size is a fundamental question in biology, but little is known about the underlying mechanisms. In the past decade, the Hippo pathway has been revealed to play a crucial role in organ size control (reviewed by [Zhao et al., 2010a ...
Bin, Zhao, Li, Li, Kun-Liang, Guan
openaire   +2 more sources

Expanding the Hippo pathway : hMOB3 modulates apoptotic MST1 signaling and supports tumor growth in glioblastoma [PDF]

open access: yes, 2014
Protein kinases are critical players of signal transduction pathways involved in development, physiological and pathological processes. Deregulation of protein kinase signaling is found to be causal or related to varieties of human diseases, such as ...
Tang, Fengyuan
core   +1 more source

Image1_Morroniside attenuates nucleus pulposus cell senescence to alleviate intervertebral disc degeneration via inhibiting ROS-Hippo-p53 pathway.jpg

open access: yes, 2022
Intervertebral disc (IVD) degeneration (IVDD) which is highly prevalent within the elderly population, is a leading cause of chronic low back pain and disability.
Yishan Bian (13809297)   +15 more
core   +1 more source

Image3_Morroniside attenuates nucleus pulposus cell senescence to alleviate intervertebral disc degeneration via inhibiting ROS-Hippo-p53 pathway.jpg

open access: yes, 2022
Intervertebral disc (IVD) degeneration (IVDD) which is highly prevalent within the elderly population, is a leading cause of chronic low back pain and disability.
Yishan Bian (13809297)   +15 more
core   +1 more source

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