Results 11 to 20 of about 114,310 (305)
Proceedings of the VLDB Endowment, 2022 Hyper-parameter optimization is crucial for pushing the accuracy of a deep learning model to its limits. However, a hyper-parameter optimization job, referred to as a study, involves numerous trials of training a model using different training knobs, and therefore is very computation-heavy, typically taking hours and days to finish.
Ahnjae Shin +4 more
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Cold Spring Harbor Perspectives in Biology, 2012 The Hippo pathway regulates tissue growth, and inactivation of any of four key components (HPO, WTS, SAV, and MATS) results in tissue overgrowth. Cell junctions may also modulate the pathway's activity.
Kieran F, Harvey, Iswar K, Hariharan
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Genes & Development, 2011 The Hippo pathway coordinates organ size and cell proliferation. The retinoblastoma family of proteins regulates progression through the G0/G1 phase of the cell cycle. Disruption of either pathway contributes to cancer formation. Three recent studies in Genes & Development reveal how cellular proliferation is coordinated between these pathways ...
Dick, Frederick A., Mymryk, Joe S.
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Frontiers in Immunology, 2023 IntroductionThe Hippo signaling pathway is an evolutionarily conserved signaling cascade that plays a crucial role in regulating cell proliferation, differentiation, and apoptosis.
Fan Mao +21 more
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eLife, 2020 The intermediate filament protein keratin 14 (K14) provides vital structural support in basal keratinocytes of epidermis. Recent studies evidenced a role for K14-dependent disulfide bonding in the organization and dynamics of keratin IFs in skin ...
Yajuan Guo +6 more
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Frontiers in Oncology, 2023 IntroductionHepatocellular carcinoma (HCC) prevalence is rising annually, but the existing treatment strategies are limited; therefore, it is crucial to explore new therapeutic approaches.MethodsHere, we investigate the potential anti-cancer mechanism of
Mingyuan Tao +3 more
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Regulation of Cardiomyocyte Proliferation by microRNAs and Small Molecules [PDF]
, 2018 Understanding the molecular mechanisms regulating cardiac cell proliferation during the embryonic, fetal and adult life holds a paramount importance in view of developing innovative strategies aimed at inducing myocardial regeneration after cardiac ...
Torrini, Consuelo
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Biodiversity Observations, 2019 Hippo cannibalism was observed at Mandavu reservoir in Hwange National Park, Zimbabwe.
Julio J. De Castro +3 more
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Developmental Cell, 2017 Normal organ growth requires precise signaling from key developmental pathways, as well as careful coordination between these pathways. In this issue of Developmental Cell, Pascual and colleagues (2017) investigate the dire consequences of simultaneous deregulation of both the Ras and Hippo pathways.
Taryn M, Sumabat, Iswar K, Hariharan
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Approaching Religion, 2018 Review of Tobias Churton's Deconstructioning Gurdjieff: Biography of a Spiritual Magician (Rochester, Inner Traditions, 2017).
Hippo Taatila
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