Results 21 to 30 of about 56,542 (314)
The critical role of the Hippo signaling pathway in kidney diseases
Frontiers in Pharmacology, 2022 The Hippo signaling pathway is involved in cell growth, proliferation, and apoptosis, and it plays a key role in regulating organ size, tissue regeneration, and tumor development.
Yuting Sun +9 more
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The EMBO Journal, 2011 The Hippo (Hpo) signalling pathway is an evolutionarily conserved pathway controlling tissue growth, but its upstream inputs remain poorly understood. In this issue of The EMBO Journal , Sansores‐Garcia et al (2011) report that modulation of filamentous (F)‐actin accumulation controls Hpo pathway activity. In a related study, Garcia‐Fernandez et al
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, 2022 Intervertebral disc (IVD) degeneration (IVDD) which is highly prevalent within the elderly population, is a leading cause of chronic low back pain and disability.
Yishan Bian (13809297) +15 more
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Premetazoan Origin of the Hippo Signaling Pathway [PDF]
, 2020 Nonaggregative multicellularity requires strict control of cell number. The Hippo signaling pathway coordinates cell proliferation and apoptosis and is a central regulator of organ size in animals. Recent studies have shown the presence of key members of
Zheng, Yonggang +3 more
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Frontiers in Immunology, 2023 IntroductionThe Hippo signaling pathway is an evolutionarily conserved signaling cascade that plays a crucial role in regulating cell proliferation, differentiation, and apoptosis.
Fan Mao +21 more
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Hippo pathway regulates caveolae expression and mediates flow response via caveolae [PDF]
, 2020 The Hippo pathway is a key regulator of cell survival, proliferation and tissue homeostasis. In addition, it is vital for development and regeneration.
Rausch, Valentina Jana Laura
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Mechanoregulation and pathology of YAP/TAZ via Hippo and non‐Hippo mechanisms [PDF]
Clinical and Translational Medicine, 2018 AbstractYes‐associated protein (YAP) and its paralog WW domain containing transcription regulator 1 (TAZ) are important regulators of multiple cellular functions such as proliferation, differentiation, and survival. On the tissue level, YAP/TAZ are essential for embryonic development, organ size control and regeneration, while their deregulation leads ...
Oleg Dobrokhotov +3 more
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eLife, 2020 The intermediate filament protein keratin 14 (K14) provides vital structural support in basal keratinocytes of epidermis. Recent studies evidenced a role for K14-dependent disulfide bonding in the organization and dynamics of keratin IFs in skin ...
Yajuan Guo +6 more
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Frontiers in Oncology, 2023 IntroductionHepatocellular carcinoma (HCC) prevalence is rising annually, but the existing treatment strategies are limited; therefore, it is crucial to explore new therapeutic approaches.MethodsHere, we investigate the potential anti-cancer mechanism of
Mingyuan Tao +3 more
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Approaching Religion, 2018 Review of Tobias Churton's Deconstructioning Gurdjieff: Biography of a Spiritual Magician (Rochester, Inner Traditions, 2017).
Hippo Taatila
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