Results 1 to 10 of about 24,046 (117)
Advanced Science, 2021 The Hippo pathway effector TAZ promotes cellular growth, survival, and stemness through regulating gene transcription. Recent studies suggest that TAZ liquid–liquid phase separation (LLPS) compartmentalizes key cofactors to activate transcription ...
Yiju Wei, Huacheng Luo, Patricia P Yee
exaly +2 more sources
FEBS Open Bio, 2015 YAP and TAZ oncoproteins confer malignancy and drug resistance to various cancer types. We screened for small molecules that inhibit the nuclear localization of YAP/TAZ.
Yusuke Oku +2 more
exaly +2 more sources
TAZ WW Domain-Mediated Regulation of Gluconeogenesis and Tumorigenesis in Hepatocellular Carcinoma through Interaction with the Glucocorticoid Receptor [PDF]
Endocrinology and MetabolismBackground Hepatocellular carcinoma (HCC) is a leading cause of cancer mortality, characterized by poor prognosis due to its high proliferative and invasive potential. Tumor metabolic reprogramming, particularly involving glucose metabolism, is essential
Hongxiang Huang +12 more
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Hadisteki İlleti Tespit ve Tenkit Prensibi Olarak: 'Filan Râvinin Rivâyetine Benzemiyor' İfadesi
Cumhuriyet İlahiyat Dergisi, 2023 Hadislerin sıhhatinin tespiti için muhaddisler tarafından hadisin sened ve metnini ilgilendiren birtakım şartlar belirlenmiştir. Bu şartların sened ve metne bakan yönleri bulunmaktadır. Bu şartlardan biri de hadisin illetli olmamasıdır. Hadisin sıhhatini
Bahadır Opus
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Biology Open, 2021 Intestinal cell lineage differentiation is a tightly regulated mechanism that involves several intracellular signaling pathways affecting the expression of a variety of transcription factors, which ultimately regulate cell specific gene expression ...
Sepideh Fallah, Jean-François Beaulieu
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Inhibition of TAZ impairs the migration ability of melanoma cells
Open Life Sciences, 2023 Malignant melanoma (MM) is characterized by rapid growth, frequent metastasis, and high mortality. Targeted therapy for MM is still a research hotspot due to the increasing understanding of the hippo pathway.
Zhang Hao +4 more
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Yurak-Samoyeds: Problems of Ethnic Identification
Арктика и Север, 2021 The article is devoted to the poorly studied problem of the origin of the name Yuraki, which the Russians, as well as the Enets and Nganasans, called the group of the Samoed-speaking population that wandered along the northern outskirts of Western ...
Yuriy N. KVASHNIN
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Cancer Biology & Medicine, 2021 Objective: Bone metastasis is a clinically important outcome of prostate carcinoma (PC). We focused on the phenotypic and functional characterization of a particularly aggressive phenotype within the androgen-independent bone metastasis-derived PC3 cell ...
Rosaria A. Fontanella +14 more
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Polish Journal of Pathology, 2022 There is growing evidence which indicates that the development and the biological features of cancer such as the invasion, metastases and recurrence are related to the presence and behavior of the cancer stem cells (CSC).
Olga Stasikowska-Kanicka +4 more
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Cells, 2020 Transcriptional coactivator with a PDZ-binding motif (TAZ) is one of the mammalian orthologs of Drosophila Yorkie, a transcriptional coactivator of the Hippo pathway. TAZ has been suggested to function as a regulator that modulates the expression of cell
Chiharu Miyajima +8 more
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