Results 181 to 190 of about 60,559 (303)

GTPBP2 inactivates Hippo signaling to promote triple-negative breast cancer cell malignancy. [PDF]

Sci Rep
Zhao X, Li W, Han Q, Xu X, Ren C, Liu W, Li X.   +6 more
europepmc   +1 more source

Drilling the Marathousa palaeo‐lake in Greece (Peloponnese): inferring the environmental context of a Middle Pleistocene archaeological site

Boreas, EarlyView.
The Megalopolis Basin is located in the central Peloponnese (Greece), a region that is situated along one of the primary Pleistocene biogeographical corridors for intracontinental hominin migration. The basin comprises several hundred metres of Plio‐Pleistocene sediments alternating between clastics and lignites.
Ines J. E. Bludau, Bernd Wagner, Uwe Kirscher, Maria Schindler, Charlotte Zachow, Johannes Schmidt, Niklas Leicher, Giovanni Muttoni, Serena Perini, Vangelis Tourloukis, Eleni Panagopoulou, Panagiotis Karkanas, Katerina Harvati, Annett Junginger   +13 more
wiley   +1 more source

Correction: The impact of inhibiting the Hippo signaling pathway effector molecule YAP1 on in vitro glioblastoma and glioblastoma stem cells. [PDF]

Sci Rep
Ozates NP, Bagca BG, Asik A, Gunduz C, Akin H, Avci CB.   +5 more
europepmc   +1 more source

MAP17 Enhances Chemoresistance and Tumorigenicity of Glioblastoma‐Initiating Cells via the Canonical NF‐кB Pathway

Cancer Science, EarlyView.
MAP 17 is identified as highly expressed in TMZ‐resistant glioblastoma‐initiating cells (GICs). MAP17 enhances GIC proliferation, TMZ resistance, and tumorigenicity through NF‐κB/RELA‐dependent BCL2 upregulation. ABSTRACT Glioblastoma (GBM) is the most common malignant brain tumor in adults.
Shenshen Dou, You Lee Son, Toru Kondo
wiley   +1 more source

CircRNA_01754 Regulates Milk Fat Production Through the Hippo Signaling Pathway. [PDF]

Animals (Basel)
Li X, Chen J, Gao R, Feng Y, Zhang Z, Chen Z.   +5 more
europepmc   +1 more source

The HIPPO pathway in gynecological malignancies

, 2020
Dong, J., He, J., Meyer, T., Wang, D., Xu, T.   +4 more
core  

Macrophage‐Specific Loss of Stearoyl‐CoA Desaturase 1 Promotes Colon Cancer by Enhancing M2 TAM Polarization

Cancer Science, EarlyView.
Macrophage‐specific Scd1 deletion accelerates colon cancer progression by suppressing the Hippo‐YAP pathway, which drives immunosuppressive M2 polarization and induces CD8+ T cell exhaustion. Pharmacological YAP activation with TT‐10 effectively reverses this microenvironment, highlighting a promising target for immunotherapy. ABSTRACT In colon cancer (
Qing You, Jiaqi Du, Ziran Wei, Yandong Liu, Weijun Wang, Wenchao Gao   +5 more
wiley   +1 more source

AKR1C3 Binds β‐Trcp to Promote the Degradation of TFRC to Protect Hepatocellular Carcinoma From Ferroptosis

Cancer Science, EarlyView.
In this study, we show that aldo‐keto reductase family 1 member C3 (AKR1C3), a protein highly expressed in ferroptosis resistant hepatocellular carcinoma cells, acts as an enzyme‐independent scaffold protein by promoting the nuclear export of β‐transducin repeat protein (β‐TrCP) and its binding to transferrin receptor (TFRC) in an enzyme‐independent ...
Lei Qi, Jingyi Hua, Di Pan, Wanwan Yang, Geng Tian, Fangyu Ye, Lingxiang Liu, Yuhan Mao, Qinglong Guo, Haopeng Sun, Li Zhao   +10 more
wiley   +1 more source

Hippo signaling pathway in cervical cancer: insights into mechanisms and therapeutic potential. [PDF]

Front Oncol
Sun Y, Zhou F, Zhong X, Lv X, Liu Y, Zhang Y, Fine RD, Li M.   +7 more
europepmc   +1 more source

Decreased Expression of FAT4 Promotes Multiple Myeloma Proliferation and Migration by Targeting the Hippo/YAP Pathway

Cancer Science, EarlyView.
This study provides the first comprehensive characterization of the functional impact, and mechanistic role of FAT4 in MM. Our findings highlight the tumor‐suppressive role of FAT4 in MM and uncover a novel mechanism by which FAT4 regulates the Hippo/YAP pathway.
Lina Zhang, Na Shen, Xin Cheng, Qinglin Shi, Lijuan Chen, Xuxing Shen   +5 more
wiley   +1 more source