Results 191 to 200 of about 36,476 (254)

Hippo Signaling Dysregulation in Breast Cancer: Subtype-Independent Gene and miRNA Signatures. [PDF]

Biomedicines
Król-Jatręga K, Mitka-Krysiak E, Boroń K, Zmarzły N, Ossowski P, Plata-Babula A, Ordon P, Kulej W, Sirek T, Gajdeczka J, Prudnikov Y, Bereza K, Nowotny-Czupryna O, Boroń D, Grabarek BO.   +14 more
europepmc   +1 more source

USP43‐mediated deubiquitination of SLC7A11 protects against LPS‐induced acute lung injury by inhibiting ferroptosis

Clinical and Translational Medicine, Volume 16, Issue 7, July 2026.
Ubiquitin‐specific protease 43 (USP43) in up‐regulated during lipopolysaccharide (LPS)‐induced acute lung injury (ALI). USP43 interacts and inhibits the degradation of solute carrier family 7 member 11 (SLC7A11) by removing the K48‐linked ubiquitination of it, thereby suppressing ferroptosis.
Li Zhang, Jutong He, Ming Xu, Bamawa Mwengendi Joël, Guiomar Correia, Xuefeng Zhou, Xinyi Li, Hexiao Tang   +7 more
wiley   +1 more source

RhoGEF2 overexpression induces cell competition dependent on Ptp10D, Crumbs and the Hippo signaling pathway. [PDF]

J Cell Sci
Fahey-Lozano N, Portela M, La Marca JE, Richardson HE.   +3 more
europepmc   +1 more source

Deep Unsupervised Domain Adaptation for Translating Cancer Dependency Maps From Cell Lines to Breast Cancer Tumor Genomics

Genetic Epidemiology, Volume 50, Issue 5, July 2026.
ABSTRACT The Cancer dependency maps (DepMap) identify genetic dependencies in cancer cells using large‐scale loss‐of‐function screens, providing a foundation for cancer‐specific treatment strategies. However, discrepancies exist between cancer cell line models (CCLs) and patient‐derived tumor models, particularly in translating findings to clinical ...
Yu Shi, Wei Xu, Pingzhao Hu
wiley   +1 more source

Metabolic stress-induced dysregulation of the Hippo signaling pathway inhibits the occurrence of hepatocarcinoma. [PDF]

Am J Cancer Res
Zhang S, Li L, Jin L, Li Z, Tao Q, Zhou F, Lu X, Zhang Q, Hu G, Huang L, Zhang L, Feng Q, Peng H, Yu Q.   +13 more
europepmc   +1 more source

Astrocyte Mechanobiology: Linking Biomechanical Forces to Biochemical Signaling in the Central Nervous System

Glia, Volume 74, Issue 7, July 2026.
Astrocytes are key sensors and transducers of biomechanical stimuli within the central nervous system. Astrocyte development is highly dependent on mechanical stimuli such as surrounding tissue stiffness and biomechanical strain. Mechanosensory pathways including integrins, connexins and pannexins, and mechanosensitive channels regulate astrocyte ...
Ana N. Strat, Alima Ahmed, Mariano Viapiano, Preethi S. Ganapathy   +3 more
wiley   +1 more source

IL-19 suppresses Hippo signaling via modulating YAP1 phosphorylation in osteoarthritis. [PDF]

Front Immunol
Deng J, Gu J, Gong X, Tang H, Cai Y, Yang Y, Dong S, Zhao C.   +7 more
europepmc   +1 more source

Immune, molecular and genetic profiles of gastric signet ring cell carcinoma: Recent progress and future challenges

International Journal of Cancer, Volume 159, Issue 1, Page 11-29, 1 July 2026.
Abstract Gastric signet ring cell carcinoma (GSRCC) is a special type of gastric cancer common in young women. Diffuse gastric cancer (DGC) begins with intramucosal lesions comprising differentiated GSRCC cells. Genetically, GSRCC and DGC are clonally identical, with their morphology influenced by extracellular Wnt signaling.
Qian Wang, Shuai Zhou, Xiongchao Fang, Xianli He, Gang Wang, Nan Wang   +5 more
wiley   +1 more source

Sodium selenite promotes apoptosis and augments autophagic flux in cervical cancer cells by activating the YAP-Hippo signaling pathway. [PDF]

Transl Cancer Res
Wang C, Zhu K, Bai L, Zhu X.
europepmc   +1 more source

PVT1 lincRNA signals an androgen‐dependent transcriptional activation program of oncogenes in prostate cancer cells

International Journal of Cancer, Volume 159, Issue 1, Page 144-158, 1 July 2026.
What's New? Unraveling the networks that regulate androgen receptor (AR) function is critical to better understanding prostate cancer development and progression. Of particular interest in this regard is the long non‐coding RNA PVT1, which regulates gene expression in cancer and is upregulated in prostate tumors.
Maria Gabriela Berzoti‐Coelho, Fabio Nunes de Mello, Ana Carolina Tahira, Gabriel Nakanishi Fortes, Agatha Fischer‐Carvalho, Pedro Jardim Poli, Murilo Sena Amaral, Sergio Verjovski‐Almeida   +7 more
wiley   +1 more source