Results 211 to 220 of about 36,476 (254)

Neu-P11 Improves Type 2 Diabetes Mellitus Immune Function by Inhibiting the Hippo Signaling Pathway. [PDF]

Int J Endocrinol
Cai S, Qi SK, Mao LN, Xie L, He J, Li YZ, Li XP.   +6 more
europepmc   +1 more source

ZEB1 Modifies VE‐Cadherin Signaling in Lymphatic Endothelial Cells

Microcirculation, Volume 33, Issue 5, July 2026.
ABSTRACT Objective Zinc finger E‐box‐binding homeobox 1 (ZEB1) is a transcription factor primarily known for its regulatory roles in epithelial‐to‐mesenchymal transition (EMT) and cell fate determination. Recent studies suggest that endothelial ZEB1 signaling promotes blood vessel growth and reduces junctional integrity, although the underlying ...
Nada S. Ahmed, Joseph L. Horder, Charles T. Cresswell, Poppy E. Harris, Amy P. Lynch, Zarah B. Tabrizi, Kathryn R. Green, James H. Hallwood, Anton C. Smith, Michael A. Portelli, Alexander J. Fezovich, Christos Spanos, David S. Gardner, Alan McIntyre, Sarah J. Storr, Daniel G. Booth, David O. Bates, Andrew V. Benest   +17 more
wiley   +1 more source

Gas plasma therapy of murine and human diabetic wounds is associated with junctional and hippo signaling and oxidative protein modifications. [PDF]

Redox Biol
Schmidt A, Wende K, Kantz L, von Woedtke T, Bekeschus S.   +4 more
europepmc   +1 more source

RRAGD p.(Ser76Leu) Variant Causes Dysregulated Expression of Muscle Development and Cytoskeleton Genes in Cardiomyocytes

The FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Under normal conditions, RagD and mTORC1 respond to amino acid changes. Upon stimulation, active mTORC1 phosphorylates S6K, 4E‐BP1, and TFEB. In response to starvation, mTORC1 is inactive. Our data indicate that the RRAGD p.(Ser76Leu) variant maintains the phosphorylation of mTORC1 targets during starvation in T‐REx HeLa cells.
Anastasia Adella, Sara B. van Katwijk, Pieter A. Leermakers, Willem B. van Ham, Hesther de Ruiter, Judita Ilgutytė, Suzanne Hendrickx, Levi Nijland, Teun P. de Boer, Eva van Rooij, Joost G. J. Hoenderop, Jeroen H. F. de Baaij   +11 more
wiley   +1 more source

Radix Scrophulariae regulates proliferation, apoptosis, and autophagy of rat thyroid cells via the MST1/Hippo signaling pathway. [PDF]

Sci Rep
Zhang N, Lu X, He JX, Ye T.
europepmc   +1 more source

Mechanism and Intervention of the NPY1R/CREB Signaling Axis in Regulating Inflammatory Response in Aged Ovarian Granulosa Cells and Ovarian Senescence

The FASEB Journal, Volume 40, Issue 12, 30 June 2026.
Aging‐associated upregulation of NPY1R drives p‐CREB activation, triggering inflammation, mitochondrial dysfunction, and extracellular matrix imbalance to promote ovarian senescence. Pharmacological inhibition of NPY1R with BIBO 3304 restores ovarian homeostasis, highlighting a therapeutic strategy for reproductive aging. ABSTRACT Ovarian senescence is
Junnan Fang, Chaoying Wang, Shuaishuai Guo, Yiping Zhang, Yang Zhang, Huihui Wang, Yue Kong, Haixia Jin, Lin Qi, Yan Liu, Zhaoting Wu, Fuli Zhang, Shuang Wen, Xiaopeng Wang, Guang Yang, Guidong Yao   +15 more
wiley   +1 more source

FAM189A2 activates Hippo signaling pathway by abrogating WWP2-mediated LATS1 ubiquitination, to inhibit the glycolysis and proliferation processes of lung adenocarcinoma. [PDF]

J Transl Med
Chen B, Rong X, Feng Y, Hou Y, Fu L, Han Q, Song Y, Lin X.   +7 more
europepmc   +1 more source

An Inhibitor of Death-Associated Protein Kinase 3 (DAPK3) Disrupts Hippo Signaling and Intestinal Epithelial Regeneration in Murine DSS-Induced Colitis. [PDF]

Dig Dis Sci
Chen HM, Carlson DA, Haystead TAJ, MacDonald JA.   +3 more
europepmc   +1 more source

The Hippo Signaling Pathway Manipulates Cellular Senescence. [PDF]

Cells
Miyajima C, Nagasaka M, Aoki H, Toriuchi K, Yamanaka S, Hashiguchi S, Morishita D, Aoyama M, Hayashi H, Inoue Y.   +9 more
europepmc   +1 more source

Caveolin-2 Knockdown Alleviated Sepsis-induced Acute Lung Injury Via Promoting Macrophage M2 Polarization and Inhibiting Apoptosis by Hippo Signaling Pathway. [PDF]

Inflammation
Xue X, Gao F, Chen J, Wang M, Wu X, Liao H, Sun Z, Nie S.   +7 more
europepmc   +1 more source