Results 121 to 130 of about 56,531 (215)

Chemogenetic Stimulation of the Dorsal Motor Nucleus of the Vagus Mitigates Autonomic Dysfunction and Memory Decline in Rat Model of Alzheimer‐Like Disease

Acta Physiologica, Volume 242, Issue 7, July 2026.
ABSTRACT Aim To test the hypothesis that Alzheimer‐like metabolic neurodegeneration rat model leads to an autonomic dysfunction, memory impairment, and hippocampal amyloid pathology and that long‐term chemogenetic stimulation of the dorsal motor nucleus of the vagus reverses these alterations. Methods Male and female transgenic Long Evans rats received
Beatriz Pacheco Sousa, Karoline Martins dos Santos, Vagner Roberto Antunes   +2 more
wiley   +1 more source

Psilocybin as a novel treatment for chronic pain

British Journal of Pharmacology, Volume 183, Issue 14, Page 3992-4005, July 2026.
Abstract Psychedelic drugs are under active consideration for clinical use and have generated significant interest for their potential as anti‐nociceptive treatments for chronic pain, and for addressing conditions like depression, frequently co‐morbid with pain.
Tate Askey, Reena Lasrado, Maria Maiarú, Gary J. Stephens   +3 more
wiley   +1 more source

In rats, neurodevelopmental disorders induced by maternal hypoxia are associated with attenuated excitatory neurotransmission in the cingulate cortex

British Journal of Pharmacology, Volume 183, Issue 13, Page 3723-3742, July 2026.
Background and Purpose Maternal hypoxia is a recognised risk factor for neurodevelopmental disorders in offspring. Although rodent models of hypoxia have been reported, the detailed pathogenesis of maternal hypoxia‐induced neurodevelopmental disorders remains unclear.
Kentaro Tokudome, Masaaki Ueki, Takujiro Homma, Shinji Matsunaga, Saki Shimizu, Yukihiro Ohno, Shuhei Tomita   +6 more
wiley   +1 more source

Glucocorticoid Receptor Translational Isoforms Generate Unique Glucocorticoid Responses in the Mouse Brain

The FASEB Journal, Volume 40, Issue 12, 30 June 2026.
GR‐A knockin mice were generated that express the classic full‐length glucocorticoid receptor (GR‐A) but lack the highly conserved translational isoforms GR‐B, GR‐C1, GR‐C2, GR‐C3, GR‐D1, GR‐D2, and GR‐D3 that have progressively shorter N‐terminal transactivation domains (NTDs).
Robert H. Oakley, Tatsuya Sueyoshi, Sivapriya Ramamoorthy, Viktoriya D. Nikolova, David R. Goulding, Jianying Li, Manas K. Ray, Sheryl S. Moy, John A. Cidlowski   +8 more
wiley   +1 more source

Human hippocampal neurogenesis in adulthood, ageing and Alzheimer's disease. [PDF]

Nature
Disouky A, Sanborn MA, Sabitha KR, Mostafa MM, Ayala IA, Bennett DA, Lu Y, Zhou Y, Keene CD, Weintraub S, Gefen T, Mesulam MM, Geula C, Maienschein-Cline M, Rehman J, Lazarov O.   +15 more
europepmc   +1 more source

Acute hyperexcitability differentially affects hippocampal neurogenesis features and spatial memory. [PDF]

Front Cell Neurosci
López-Ibarra D, Aguilar-Arredondo A, Gaytan-Zeron V, Hernández-Mercado K, Montiel T, Osorio-Gómez D, Zepeda A.   +6 more
europepmc   +1 more source

Dexmedetomidine Preserves Hippocampal Neurogenesis During Recovery from Neonatal Hyperoxia in Rats. [PDF]

Cells
Endesfelder S, Bührer C, Schmitz T.
europepmc   +1 more source

Humanised Environmental Enrichment: Spatial Effects of Cities and Buildings on Adult Hippocampal Neurogenesis in Humans. [PDF]

Int J Mol Sci
Khalil MH.
europepmc   +1 more source

Manic switching from depression is affected by adult hippocampal neurogenesis. [PDF]

Anim Cells Syst (Seoul)
Song J, Kim W, Park Y, Lee JM, Kim JH, Park DH, Lee HJ, Shin KS, Kim HJ, Geum D.   +9 more
europepmc   +1 more source

Comparative analysis of maze complexity: implications for adult hippocampal neurogenesis. [PDF]

Front Neurosci
Khalil MH.
europepmc   +1 more source