Results 221 to 230 of about 101,099 (274)

Dihydrotestosterone and Finasteride Effects on Alcohol Cue‐Elicited Brain Activity in Males With Heavy Episodic Drinking

Addiction Biology, Volume 31, Issue 2, February 2026.
In a randomized, double‐blind, placebo‐controlled crossover study, we investigated whether finasteride‐induced reduction of dihydrotestosterone alters alcohol cue‐elicited brain activity and craving in males with heavy episodic drinking. Although dihydrotestosterone concentrations were not associated with neural cue reactivity, finasteride increased ...
Rafat Boroumand‐Jazi, Sabine Hoffmann, Iris Reinhard, Patrick Bach, Wolfgang H. Sommer, Marlene Kundlacz, Christian P. Müller, Matthias Reichl, Haoye Tan, Leonard P. Wenger, Anne Beck, Sabine Vollstädt‐Klein, Falk Kiefer, Christiane Mühle, Sarah Gerhardt, Bernd Lenz   +15 more
wiley   +1 more source

High-Phenolic Cocoa Enhances Drug-Induced Reinstatement of Cocaine-Conditioned Place Preference Independently of Increasing Adult Hippocampal Neurogenesis. [PDF]

Food Sci Nutr
Melgar-Locatelli S, Mañas-Padilla MDC, Rivera P, Rodríguez-Pérez C, Castilla-Ortega E.   +4 more
europepmc   +1 more source

Dysregulation of Rho‐Associated Coiled‐Coil Protein Kinase1 Depletes Neural Stem Cell Pool and Impairs Hippocampal Neurogenesis After Traumatic Brain Injury

Cell Proliferation, Volume 59, Issue 2, February 2026.
Following TBI, hippocampal neurogenesis in mice is impaired and affects cognitive function. This impairment is associated with the upregulation of p‐AKT/AKT mediated by ROCK1. ABSTRACT Traumatic brain injury (TBI) represents a global health burden, often resulting in persistent neurological deficits due to impaired hippocampal neurogenesis ...
Chaoqun Yao, Long Jin, Jun Zhong, Qianying Huang, Zhongwei Bao, Shaolong Zhou, Chaohua Wang, Huanhuan Li, Xiaowei Yuan, Zhen Wang, Ning Du, Jingxuan Yu, Huanran Chen, Xuyang Zhang, Hongfei Ge, Jianheng Wu   +15 more
wiley   +1 more source

Survey of transcriptome analyses of hippocampal neurogenesis with focus on adult dentate gyrus stem cells. [PDF]

Front Cell Dev Biol
Micheli L, Caruso M, D'Andrea G, Volpe D, Ceccarelli M, Tirone F.   +5 more
europepmc   +1 more source

Glucocorticoid‐Induced Tumor Necrosis Factor Receptor Ligand: Correlation and Therapeutic Potential for Cognitive Impairment in Temporal Lobe Epilepsy

Clinical and Translational Science, Volume 19, Issue 2, February 2026.
ABSTRACT Immune checkpoint regulators can improve neurological functions in Alzheimer's disease. However, it remains blurred whether these regulators may ameliorate temporal lobe epilepsy (TLE) and TLE‐related cognitive impairment. This study analyzed the bulk transcriptomic data of human TLE hippocampi by bioinformatics.
Man Li, Jinying Shi, Xiaodong Pan, Huapin Huang   +3 more
wiley   +1 more source

Stk24 deficiency causes disrupted hippocampal neurogenesis and anxiety-like behavior in mice. [PDF]

Commun Biol
Wu KY, Tsao CH, Su NC, Deng SM, Huang GJ.   +4 more
europepmc   +1 more source

Targeted Nanodelivery of WGX50 and Curcumin via Gold Nanoparticles for Alzheimer's Therapy

Journal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder, posing a global health challenge. It affects millions of people, causing cognitive decline and a heavy burden on healthcare systems. Neuroinflammation is a key pathological feature of AD, often associated with the dysregulation of microRNAs such as hsa‐miR‐146a‐5p. WGX50 (N‐[
Madeeha Shahzad Lodhi, Muhammad Maisam, Muhammad Tahir Khan, Amina Bibi, Dongqing Wei, Kejie Mou   +5 more
wiley   +1 more source

SARS-CoV-2 vaccination during pregnancy enhances offspring hippocampal neurogenesis and working memory via IFN-γ-responsive microglia. [PDF]

Commun Biol
Tang J, Qi F, Zou J, Liu H, Zuo Z, Wang L, Wang N, Li Z, Kumar A, Guo K, Hu D, Yao Z.   +11 more
europepmc   +1 more source

Bidirectional Communication Between Astrocytes and Neurons via Extracellular Vesicles: A Multi‐Omics Approach

Journal of Neurochemistry, Volume 170, Issue 2, February 2026.
Schematic diagram illustrating the communication between mouse hippocampal astrocytes and neurons through extracellular vesicles (EVs). The illustration highlights unique proteins secreted by each cell type within EVs, with vesicle size proportional to the concentration of secreted proteins.
Daria Hajka, Paulina Żebrowska‐Różańska, Katarzyna Romańczuk, Jacek R. Wiśniewski, Łukasz Łaczmański, Norbert Łodej, Krzysztof J. Pawlik, Dariusz Rakus, Agnieszka Gizak   +8 more
wiley   +1 more source