Results 251 to 260 of about 101,099 (274)

Neuropeptides and hippocampal neurogenesis

Neuropeptides, 2013
Hippocampal neurogenesis is important for modulating the behavioural responses to stress and for certain forms of learning and memory. The mechanisms underlying the necessary coupling of neuronal activity to neural stem/progenitor cell (NSPC) function remain poorly understood. Within the dentate subgranular stem cell niche, local interneurons appear to
M J, Zaben, W P, Gray
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Stress and hippocampal neurogenesis

Biological Psychiatry, 1999
The dentate gyrus of the hippocampal formation develops during an extended period that begins during gestation and continues well into the postnatal period. Furthermore, the dentate gyrus undergoes continual structural remodeling in adulthood. The production of new granule neurons in adulthood has been documented in a number of mammalian species ...
E, Gould, P, Tanapat
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Ghrelin mediated hippocampal neurogenesis

2022
The stomach hormone, ghrelin, which is released during food restriction, provides a link between circulating energy state and adaptive brain function. The maintenance of such homeostatic systems is essential for an organism to survive and thrive, and accumulating evidence points to ghrelin being a key regulator of adult hippocampal neurogenesis and ...
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Neurogenesis in hippocampal slice cultures

Molecular and Cellular Neuroscience, 2004
A major challenge in studying neurogenesis in the adult brain is gaining access to neural stem cells for experimental manipulation. We developed an approach utilizing mouse hippocampal organotypic cultures to characterize neurogenesis under controlled conditions.
Raineteau, Olivier, Rietschin, Lotty, Gradwohl, Gérard, Guillemot, François, Gähwiler, Beat   +4 more
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Adult hippocampal neurogenesis in depression

Nature Neuroscience, 2007
The development of new treatments for depression is predicated upon identification of neural substrates and mechanisms that underlie its etiology and pathophysiology. The heterogeneity of depression indicates that its origin may lie in dysfunction of multiple brain regions.
Amar, Sahay, Rene, Hen
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Adult hippocampal neurogenesis and aging

European Archives of Psychiatry and Clinical Neuroscience, 2007
The demographic changes in the foreseeable future stress the need for research on successful cognitive aging. Advancing age constitutes a primary risk factor for disease of the central nervous system most notably neurodegenerative disorders. The hippocampus is one of the brain regions that is prominently affected by neurodegeneration and functional ...
Friederike, Klempin, Gerd, Kempermann
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Hippocampal Neurogenesis in Epileptogenesis

Neuroscience and Behavioral Physiology, 2020
This review presents data on the characteristics of the reorganization of the hippocampus associated with impairment to neurogenesis in epileptiform states of different etiologies. Data on the effects of convulsive states of different severities and frequencies on the levels of proliferation, migration, and insertion of new cells into the hippocampal ...
E. V. Nasluzova, M. V. Glazova, E. V. Chernigovskaya   +2 more
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Antidepressants and Hippocampal Neurogenesis

Science, 2003
Antidepressants can cause rapid increases in serotonin and noradrenaline levels in patients, but usually the clinical benefits are not seen until 3 or 4 weeks have passed. One possible explanation for this delay is that antidepressant drugs change the mood of patients by stimulating neurogenesis.
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Hippocampal Neurogenesis and Ageing

2012
Although significant inconsistencies remain to be clarified, a role for neurogenesis in hippocampal functions, such as cognition, has been suggested by several reports. Yet, investigation in various species of mammals, including humans, revealed that rates of hippocampal neurogenesis are steadily declining with age.
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Adult hippocampal neurogenesis and antidepressants effects

Current Opinion in Pharmacology, 2020
The hippocampus is particularly involved in cognitive processes and is a key regulator of stress responses and emotions. Therefore, the role of adult-born neurons in this region has become a crucial field of research in order to understand mood and stress disorders, such as major depression.
Barbara, Planchez, Alexandre, Surget, Catherine, Belzung   +2 more
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