Results 261 to 270 of about 101,099 (274)
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Inflammatory Blockade Restores Adult Hippocampal Neurogenesis
Science, 2003Cranial radiation therapy causes a progressive decline in cognitive function that is linked to impaired neurogenesis. Chronic inflammation accompanies radiation injury, suggesting that inflammatory processes may contribute to neural stem cell dysfunction.
Michelle L, Monje +2 more
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GABAergic Regulation of Adult Hippocampal Neurogenesis
Molecular Neurobiology, 2016Adult hippocampal neurogenesis has been implicated in several brain functions, including learning and memory processes. It also plays an important role in the aetiology of anxiety disorders, depression and age-related deficits. The endogenous stem cell pool is also known to hold great potential for ameliorating the diseased or aged brain.
Sibbe, Mirjam, Kulik, Akos
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Hippocampal Neurogenesis: A Matter of Survival
American Journal of Psychiatry, 2007The hippocampus has long been known to play a prominent role in establishing new memories. More recently, the hippocampus has been implicated in several psychiatric illnesses (e.g., Alzheimer’s disease, schizophrenia, depression) and may even play a role in the traumatic memories central to PTSD.
Diane C, Lagace +2 more
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NPY and Hippocampal Neurogenesis
2005The chronic behavioural and cognitive effects of NPY may be partly mediated by Y1 receptor effects on stem cell proliferation and neurogenesis in the dentate gyrus of the adult hippocampus. Further investigation of this mechanism of NPY function is likely to be helpful is dissociating the acute and chronic effects of NPY on cognition and behaviour and ...
William P. Gray, Helen E. Scharfman
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Adult Hippocampal Neurogenesis
2010Abstract In the dentate gyrus of mammals, including humans, adult hippocampal neurogenesis lifelong generates one single type of excitatory neurons, new granule cell neurons, which contribute to the mossy fiber connection between the dentate gyrus and area CA3. Adult hippocampal neurogenesis originates from a unique radial glia-like stem
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Working memory training decreases hippocampal neurogenesis
Neuroscience, 2006The relationship between adult hippocampal neurogenesis and cognition appears more complex than suggested by early reports. We aimed to determine if the duration and task demands of spatial memory training differentially affect hippocampal neurogenesis.
P, Mohapel +3 more
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Hippocampal neurogenesis and depression.
Novartis Foundation symposium, 2008Various chronic antidepressant treatments increase adult hippocampal neurogenesis, but the functional importance of this phenomenon remains unclear. Using radiological and genetic methods, we show that disrupting neurogenesis blocks behavioural responses to antidepressants.
Amar, Sahay, René, Hen
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