Results 101 to 110 of about 511,468 (345)
Hippocampal Sclerosis and Cognitive Dysfunction
Pediatric Neurology Briefs, 1997 Deficits of cognitive function, including language development and learning of complex social skills, typical of mental deficiency and autism, are reported in 4 children with bilateral hippocampal sclerosis and epilepsy followed at Duke University ...
J Gordon Millichap
doaj +1 more source
Hippocampal sclerosis, hippocampal neuron loss patterns and TDP‐43 in the aged population
Brain Pathology, 2017 Hippocampal neuron loss is a common neuropathological feature in old age with various underlying etiologies. Hippocampal sclerosis of aging (HS‐Aging) is neuropathologically characterized by severe CA1 neuronal loss and frequent presence of transactive ...
Suvi R K Hokkanen +6 more
semanticscholar +1 more source
Deep brain and cortical stimulation for epilepsy [PDF]
, 2014 Background : Despite optimal medical treatment, including epilepsy surgery, many epilepsy patients have uncontrolled seizures. In the last decades, interest has grown in invasive intracranial neurostimulation as a treatment for these patients ...
Anderson +63 more
core +1 more source
Nanomedicines Against Mitochondrial Dysfunction‐Induced Metabolic Diseases
Advanced Science, EarlyView.Mitochondrial dysfunction is central to metabolic diseases. Nanomedicine offers transformative approaches for restoring function via targeted delivery, responsive release, and multimodal therapy. This review outlines the pathological basis, nanocarrier design, organelle‐specific targeting, recent advances, and future clinical translation challenges ...
Ke Xu +9 more
wiley +1 more source
Neurocognitive and Seizure Outcomes of Selective Amygdalohippocampectomy versus Anterior Temporal Lobectomy for Mesial Temporal Lobe Epilepsy. [PDF]
, 2014 Objective. To report our institutional seizure and neuropsychological outcomes for a series of patients with mesial temporal lobe epilepsy (mTLE) undergoing anterior temporal lobectomy (ATL) or selective amygdalohippocampectomy (SelAH) between 2004 and ...
Andrade, Danielle +10 more
core +3 more sources
Research Progress on Idebenone in Neurodegenerative Diseases
AGING MEDICINE, EarlyView.The study not only summarizes the biological properties of Idebenone (IDE), including its role in improving mitochondrial function and antioxidative stress, but also explores its clinical research progress in various neurodegenerative diseases, providing a new perspective for the treatment of these disorders.
Yanqing Zhang +10 more
wiley +1 more source
Functionalization and Characterization of Magnetic Nanoparticles for the Detection of Ferritin Accumulation in Alzheimer's Disease [PDF]
, 2018 Early diagnosis in Alzheimer's disease (AD), prior to the appearance of marked clinical symptoms, is critical to prevent irreversible neuronal damage and neural malfunction that lead to dementia and death.
Cussó, Lorena +4 more
core +1 more source
Advanced Intelligent Systems, EarlyView.A novel medical image segmentation framework that integrates an enhanced Particle Swarm Optimization (EE‐PSO) into DeepLabV3+ to optimize feature selection. By dynamically identifying key channels in the atrous spatial pyramid pooling module, the method improves segmentation performance, achieving mIoU gains of 2.7% on Alzheimer's and 2.8% on brain ...
Alireza Norouziazad +8 more
wiley +1 more source
Temporal Lobectomy for Epilepsy with Congenital Porencephaly and Hippocampal Sclerosis
Pediatric Neurology Briefs, 2003 The clinical characteristics and surgical outcome of 6 patients with intractable epilepsy and coexisting extratemporal porencephaly and hippocampal sclerosis are presented from the University of Alabama, Birmingham, AL.
J Gordon Millichap
doaj +1 more source