Results 101 to 110 of about 41,234 (255)

Status epilepticus: Updates on mechanisms and treatments

Epilepsia Open, EarlyView.
Abstract Status epilepticus (SE) consists of prolonged, self‐sustaining seizures and is a common neurological emergency that causes respiratory compromise and neuronal injury. Without prompt treatment, the seizures can become resistant to benzodiazepines, leading to the progressive evolution of established, refractory, and super‐refractory SE.
Suchitra Joshi, Jaideep Kapur
wiley   +1 more source

Cognitive safety under epicranial cortex stimulation of the epileptic focus

Epilepsia Open, EarlyView.
Abstract Epicranial focal cortex stimulation (FCS) is a new CE‐certified treatment for pharmacoresistant focal epilepsy. In a multicenter observational trial, we report cognitive tolerability in 11 patients with pharmacoresistant epilepsy undergoing epicranial focal cortex stimulation (eFCS) over the predominant seizure focus (left temporal (N = 4 ...
Kathrin Wagner, Iris Gorny, Julia Kustermann, Jessika Paula Losacker, Birgitta Metternich, Julia Berg, Bastian E. A. Sajonz, Volker Arnd Coenen, Elisabeth Kaufmann, Susanne Knake, Andreas Schulze‐Bonhage   +10 more
wiley   +1 more source

Clinical outcomes and learning curve of MRgLITT system for drug‐resistant epilepsy in China: A single‐center retrospective study

Epilepsia Open, EarlyView.
Abstract Objective Magnetic resonance‐guided laser interstitial thermal therapy (MRgLITT) is a minimally invasive technique that allows for real‐time magnetic resonance imaging (MRI) monitoring and precise ablation of epileptogenic lesions. This study reports our initial clinical experience with a domestically developed MRgLITT system in patients with ...
Sichang Chen, Yang Dai, Xiaotong Fan, Yihe Wang, Penghu Wei, Yongzhi Shan, Guoguang Zhao   +6 more
wiley   +1 more source

Semiology in spontaneous versus cortical stimulation‐induced seizures during SEEG: A within‐patient comparison study

Epilepsia Open, EarlyView.
Abstract Objective We aimed to study the concordance of seizure semiology in direct electrical stimulation‐induced seizures (SIS) compared to spontaneous seizures during stereoelectroencephalography (SEEG) and to report on patient‐level variables associated with habitual and atypical SIS.
Marai Mahizhnan, Stéphane Dufau, John Phamnguyen, Arash Kahrom, Donald Craig, Aileen McGonigal   +5 more
wiley   +1 more source

Long-term hippocampal low-frequency stimulation alleviates focal seizures, memory deficits and synaptic pathology in epileptic mice

Neurobiology of Disease
Background: Mesial temporal lobe epilepsy (MTLE) is a prevalent form of focal epilepsy characterized by seizures originating from the hippocampus and adjacent regions.
Piret Kleis, Enya Paschen, Andrea Djie-Maletz, Andreas Vlachos, Carola A. Haas, Ute Häussler   +5 more
doaj   +1 more source

Neuropsychological correlations with fornix and hippocampus in temporal lobe epilepsy demonstrated with diffusion tensor imaging

Epilepsia Open, EarlyView.
Abstract Objective Memory dysfunction is a common disabling comorbidity in temporal lobe epilepsy (TLE) and hippocampal sclerosis (HS). While bilateral fornix diffusion abnormalities have been reported in TLE using diffusion tensor imaging (DTI), the impact of fornix pathology on cognitive outcomes remains unclear.
Seyed Amir Ali Adel, Jordan Urlacher, Christian Beaulieu, Donald W. Gross   +3 more
wiley   +1 more source

Scalp fast oscillations detected by high‐density EEG as a noninvasive predictor of surgical outcome in temporal lobe epilepsy with hippocampal sclerosis

Epilepsia Open, EarlyView.
Abstract Objective To evaluate whether scalp oscillatory patterns—particularly scalp fast oscillations (SFOs) (>30 Hz) detected using 256‐channel high‐density EEG (HD‐EEG)—are associated with and can predict surgical outcomes in patients with drug‐resistant temporal lobe epilepsy with hippocampal sclerosis (TLE‐HS) undergoing anterior temporal ...
Pongsakorn Kongsakorn, Suda Jirasakuldej, Peerasit Treesuthacheep, Totsapol Surawattanawong, Chusak Limotai   +4 more
wiley   +1 more source

Structural brain imaging biomarkers for predicting seizure recurrence after a first unprovoked seizure

Epilepsia Open, EarlyView.
Abstract Objectives Predicting seizure recurrence following a first unprovoked seizure (FUS) remains a significant clinical challenge, especially when routine clinical magnetic resonance imaging (MRI) and EEG do not reveal abnormalities diagnostic of epilepsy.
Suyi Ooi, Chris Tailby, Heath R. Pardoe, Patrick W. Carney, Moksh Sethi, Jonas Haderlein, Graeme D. Jackson, David N. Vaughan   +7 more
wiley   +1 more source

Diagnostic reassessment in patients previously diagnosed with childhood‐onset epilepsy during the transition to adult care: A retrospective cohort study in a tertiary epilepsy center

Epilepsia Open, EarlyView.
Abstract Objective To investigate the frequency, predictors, and clinical implications of diagnostic reassessment in patients previously diagnosed with childhood‐onset epilepsy during the transition period to adult care at a tertiary epilepsy center. Methods We conducted a retrospective cohort study of 317 patients previously diagnosed with childhood ...
Tetsuhiro Fukuyama, Masaru Nasuno, Manami Yabe, Makoto Nishioka, Yumi Hoshino, Takenori Natsume, Kohei Kanaya, Kyoko Takano, Tomoki Kaneko, Yushi Inoue   +9 more
wiley   +1 more source

Response: Hippocampal Sclerosis [PDF]

Epilepsia, 2004
Adrian Lowe, Christine Kilpatrick, Terence J. O'Brien   +2 more
openaire   +1 more source