Results 151 to 160 of about 633,597 (336)

Hippocampal systems for event encoding and sequencing during ongoing narrative comprehension

Communications Biology
Narrative comprehension requires encoding individual events and sequencing them into coherent structures. This study demonstrates how the hippocampus contributes to these processes during ongoing narrative processing.
Jiwoong Park, Hayoung Song, Won Mok Shim
doaj   +1 more source

Microglial Deletion of Hrh4 Alleviates Alzheimer's Disease Pathologies by Enhancing Microglial Phagocytosis of Amyloid‐β and Tau

Advanced Science, EarlyView.
Histamine H4 receptor (H4R) antagonist VUF6002 mimics low‐dose X‐ray irradiation in aged Alzheimer's disease (AD) mice, enhancing microglial clearance of amyloid‐beta/hyperphosphorylated tau aggregates and restoring cognition. Microglial H4R deletion activates cAMP/TGF‐β1/Smad3 pathway, enhancing phagocytosis, while TGF‐β receptor 1 deletion abolishes ...
Yi‐Jun Xu, Tan Wu, Larry Tso‐Lun Lo, Chi‐Chiu Ko, Xin Wang, Chi Him Eddie Ma   +5 more
wiley   +1 more source

Movement arrest and the hippocampus [PDF]

, 1977
D. Caroline Blanchard, Robert J. Blanchard, Eugene M. C. Lee, Kenneth K. Fukunaga   +3 more
openalex   +1 more source

NADPH Oxidase Inhibition Promotes Brain Resilience by Attenuating Tauopathy and Neuroinflammation in Alzheimer's Disease

Advanced Science, EarlyView.
CRB‐2131, as a novel Nox inhibitor, suppresses brain oxidation, tauopathy, and neuro‐inflammation, thereby preventing death of mature neurons and promoting regeneration of immature neurons. Ultimately, this fosters a resilient brain and protects cognition.
Jihyeon Lee, Seunghwan Sim, Yinglan Jin, Hyejun Park, Eun Young Byeon, Su Jin Kim, Sujin Yun, Hye Eun Lee, Da Un Jeong, Jung Min Suh, In Hye Lee, Ho‐Young Lee, Yongseok Choi, Yun Soo Bae   +13 more
wiley   +1 more source

VI. The hippocampus

, 1893
Alex Hill
openalex   +1 more source

Elevated Apolipoprotein E Expression in Hippocampal Microglia Drives Temporal Lobe Epilepsy Progression

Advanced Science, EarlyView.
In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi, Zesheng Li, Xin Sun, Yanfeng Yang, Yumin Luo, Ziang Song, Hengxin Dong, Lei Jin, Jing Xie, Yongzhi Shan, Guoguang Zhao   +10 more
wiley   +1 more source

Review of the seahorses {Hippocampus) found on the coasts of the American continents and of Europe

, 1937
Isaac Ginsburg
openalex   +2 more sources

The effect of ECS on the hippocampus [PDF]

, 1973
Joseph B. Keyes
openalex   +1 more source

Identifying Tipping Points during Healthy Brain Aging through Single‐Nucleus Transcriptomic Analysis

Advanced Science, EarlyView.
This study applies single‐nucleus transcriptomics and systems dynamics to uncover nonlinear aging patterns in healthy human brains. By introducing dynamic network biomarker theory, the authors identify a critical tipping point at ages 56–60 during aging, and highlight glial instability as a key mediator.
Peiru Wu, Xuyu Zhao, Zixin Chen, Jingying Huang, Tengteng Dai, Jianxin Zhou, Luyao Xiao, Luonan Chen, Robert Chunhua Zhao, Jiao Wang   +9 more
wiley   +1 more source

Nanocatalytic Neuroprotection and Neurological Recovery Post‐Traumatic Brain Injury

Advanced Science, EarlyView.
This study demonstrates that combining Ce0.7Zr0.3O2 nanozymes with nimodipine enhances neuroprotection after traumatic brain injury. The therapy reduces oxidative stress, neuronal apoptosis, and improves blood–brain barrier integrity, with nanozymes effective at low doses.
Xinjie Hong, Liang Zhao, Xianzheng Sang, Chao Ma, Meiqi Chang, Xinran Song, Wei Feng, Tao Xu, Li Ding, Yu Chen, Lijun Hou   +10 more
wiley   +1 more source