Results 51 to 60 of about 601,318 (311)

May we routinely spare hippocampal region in primary central nervous system lymphoma during whole brain radiotherapy?

open access: yesRadiation Oncology, 2023
Purpose One of the main limiting factors of whole-brain radiation therapy (WBRT) for primary central nervous system lymphoma (PCNSL) is the impairment of neurocognitive functions (NCFs), which is mainly caused by radiation-induced injury to the ...
Ciro Mazzarella   +20 more
doaj   +1 more source

The microbiota-gut- hippocampus axis

open access: yesFrontiers in Neuroscience, 2022
IntroductionIt is well known that the intestinal bacteria substantially affect physiological processes in many body organs. Especially, through a bidirectional communication called as gut-microbiota-brain axis, the gut microbiota deeply influences ...
Mahmoud Salami, Masoud Soheili
doaj   +1 more source

Soman induces endoplasmic reticulum stress and apoptosis of cerebral organoids via the GRP78‐ATF6‐CHOP signaling pathway

open access: yesFEBS Open Bio, EarlyView.
Cerebral organoids were employed as a novel model to explore the neurotoxicity of soman. Soman inhibited acetylcholinesterase activity, increased cell apoptosis and upregulated endoplasmic reticulum (ER) stress markers glucose‐regulated protein 78 (GRP78), activating transcription factor 6 (ATF6) and C/EBP homologous protein (CHOP).
Yue Wei   +7 more
wiley   +1 more source

Neural systems supporting navigation [PDF]

open access: yes, 2014
Highlights: • Recent neuroimaging and electrophysiology studies have begun to shed light on the neural dynamics of navigation systems. • Computational models have advanced theories of how entorhinal grid cells and hippocampal place cells might ...
Barry, C, Spiers, HJ
core   +1 more source

Circadian Oscillations within the Hippocampus Support Hippocampus-dependent Memory Processing

open access: yesFrontiers in Molecular Neuroscience, 2012
The ability to sustain memories over long periods of time, sometimes even a lifetime, is one of the most remarkable properties of the brain. Much knowledge has been gained over the past few decades regarding the molecular correlates of memory formation.
Kristin Lynn Eckel-Mahan
doaj   +1 more source

Semi‐automated hippocampal avoidance whole‐brain radiotherapy planning

open access: yesJournal of Applied Clinical Medical Physics, EarlyView.
Abstract Background Hippocampal avoidance whole‐brain radiotherapy (HA‐WBRT) is designed to spare cognitive function by reducing radiation dose to the hippocampus during the treatment of brain metastases. Current manual planning methods can be time‐consuming and may vary in quality, necessitating the development of automated approaches to streamline ...
Dong Joo Rhee   +9 more
wiley   +1 more source

Dorsal-Ventral Differences in Modulation of Synaptic Transmission in the Hippocampus

open access: yesFrontiers in Synaptic Neuroscience, 2020
Functional diversification along the longitudinal axis of the hippocampus is a rapidly growing concept. Modulation of synaptic transmission by neurotransmitter receptors may importantly contribute to specialization of local intrinsic network function ...
George Trompoukis   +1 more
doaj   +1 more source

Progressive Myoclonus Epilepsy: Distinctive MRI Changes in Cerebellar and Motor Networks

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Progressive myoclonus epilepsy (PME) is a rare generalized epilepsy syndrome with a well‐characterized genetic basis. The brain networks that are affected to give rise to the distinctive symptoms of PME are less well understood. Methods Eleven individuals with PME with a confirmed genetic diagnosis and 22 controls were studied.
Jillian M. Cameron   +3 more
wiley   +1 more source

Feedback Chain Network For Hippocampus Segmentation [PDF]

open access: yesarXiv, 2022
The hippocampus plays a vital role in the diagnosis and treatment of many neurological disorders. Recent years, deep learning technology has made great progress in the field of medical image segmentation, and the performance of related tasks has been constantly refreshed.
arxiv  

Hippocampal Infusion of Zeta Inhibitory Peptide Impairs Recent, but Not Remote, Recognition Memory in Rats. [PDF]

open access: yes, 2015
Spatial memory in rodents can be erased following the infusion of zeta inhibitory peptide (ZIP) into the dorsal hippocampus via indwelling guide cannulas.
Broadbent, Nicola J   +3 more
core   +4 more sources

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