Results 61 to 70 of about 518,995 (209)

Hydrogen Sulfide Prevents LPS-Induced Depression-like Behavior through the Suppression of NLRP3 Inflammasome and Pyroptosis and the Improvement of Mitochondrial Function in the Hippocampus of Mice

open access: yesBiology, 2023
Hydrogen sulfide (H2S) has been implicated to have antidepressive effects. We sought to investigate the prevention effects of H2S donor NaHS on depression-like behavior induced by lipopolysaccharide (LPS) in mice and its potential mechanisms.
Peng Bao   +6 more
doaj   +1 more source

Hippocampal Infusion of Zeta Inhibitory Peptide Impairs Recent, but Not Remote, Recognition Memory in Rats. [PDF]

open access: yes, 2015
Spatial memory in rodents can be erased following the infusion of zeta inhibitory peptide (ZIP) into the dorsal hippocampus via indwelling guide cannulas.
Broadbent, Nicola J   +3 more
core   +4 more sources

DeepHIPS: A novel Deep Learning based Hippocampus Subfield Segmentation method [PDF]

open access: yesarXiv, 2020
The automatic assessment of hippocampus volume is an important tool in the study of several neurodegenerative diseases such as Alzheimer's disease. Specifically, the measurement of hippocampus subfields properties is of great interest since it can show earlier pathological changes in the brain. However, segmentation of these subfields is very difficult
arxiv  

Serotonin Receptors in Hippocampus [PDF]

open access: yesThe Scientific World Journal, 2012
Serotonin is an ancient molecular signal and a recognized neurotransmitter brainwide distributed with particular presence in hippocampus. Almost all serotonin receptor subtypes are expressed in hippocampus, which implicates an intricate modulating system, considering that they can be localized as autosynaptic, presynaptic, and postsynaptic receptors ...
Angelina Rodríguez   +4 more
openaire   +5 more sources

Female rat hippocampal cell density after conditioned place preference [PDF]

open access: yes, 2014
The hippocampus is important for learning tasks, such as conditioned place preference (CPP), which is widely used as a model for studying the reinforcing effects of drugs with dependence liability.
Babakordi, F.   +3 more
core  

Hippocampus and retrosplenial cortex combine path integration signals for successful navigation [PDF]

open access: yes, 2013
The current study used fMRI in humans to examine goal-directed navigation in an open field environment. We designed a task that required participants to encode survey-level spatial information and subsequently navigate to a goal location in either first ...
Brown, Thackery I   +5 more
core   +3 more sources

Brain muscarinic cholinergic receptors in Huntington's disease [PDF]

open access: yes, 1992
Muscarinic cholinergic receptors and choline acetyltransferase (ChAT) activity were studied in postmortem brain tissue from patients with Huntington's disease and matched control subjects.
Agid, Y.   +4 more
core   +1 more source

Cholinergic Deficit Induced by Central Administration of 192IgG-Saporin Is Associated With Activation of Microglia and Cell Loss in the Dorsal Hippocampus of Rats

open access: yesFrontiers in Neuroscience, 2019
Alzheimer’s disease (AD) is associated with degeneration of cholinergic neurons in the basal forebrain. Administration of the immunotoxin 192IgG-saporin to rats, an animal model of AD, leads to degeneration of cholinergic neurons in the medial septal ...
Yulia V. Dobryakova   +9 more
doaj   +1 more source

The differentiation and integration of the hippocampal dorsoventral axis are controlled by two nuclear receptor genes

open access: yeseLife, 2023
The hippocampus executes crucial functions from declarative memory to adaptive behaviors associated with cognition and emotion. However, the mechanisms of how morphogenesis and functions along the hippocampal dorsoventral axis are differentiated and ...
Xiong Yang   +6 more
doaj   +1 more source

Gamma radiation-induced impairment of hippocampal neurogenesis, comparison of single and fractionated dose regimens Deterioro de la neurogénesis en el hipocampo inducida por radiación gamma, comparación de los regímenes de dosis única y fraccionada [PDF]

open access: yes, 2012
Radiation therapy of the brain is associated with many consequences, including cognitive disorders. Pathogenesis of radiation induced cognitive disorder is not clear, but reduction of neurogenesis in hippocampus may be an underlying reason. 24 adult male
Azami, N.S.   +2 more
core  

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