Results 61 to 70 of about 776,116 (376)

Structural imaging biomarkers of sudden unexpected death in epilepsy. [PDF]

open access: yes, 2015
Sudden unexpected death in epilepsy is a major cause of premature death in people with epilepsy. We aimed to assess whether structural changes potentially attributable to sudden death pathogenesis were present on magnetic resonance imaging in people who ...
Balestrini, Simona   +12 more
core   +3 more sources

Quantitative Iron Measurements in the Basal Ganglia of NBIA Patients Using QSM: Insights From a Tertiary Center

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurodegeneration with brain iron accumulation (NBIA) comprises rare genetic disorders characterized by predominantly extrapyramidal symptoms and iron deposition in the basal ganglia. Conventional magnetic resonance imaging (MRI) detects qualitative changes but cannot accurately quantify iron accumulation. Quantitative susceptibility
Özge Uygun   +19 more
wiley   +1 more source

Dopamine loss alters the hippocampus-nucleus accumbens synaptic transmission in the Tg2576 mouse model of Alzheimer's disease

open access: yesNeurobiology of Disease, 2018
The functional loop involving the ventral tegmental area (VTA), dorsal hippocampus and nucleus accumbens (NAc) plays a pivotal role in the formation of spatial memory and persistent memory traces.
Alberto Cordella   +11 more
doaj   +1 more source

Dorsal-Ventral Differences in Modulation of Synaptic Transmission in the Hippocampus

open access: yesFrontiers in Synaptic Neuroscience, 2020
Functional diversification along the longitudinal axis of the hippocampus is a rapidly growing concept. Modulation of synaptic transmission by neurotransmitter receptors may importantly contribute to specialization of local intrinsic network function ...
George Trompoukis   +1 more
doaj   +1 more source

Structural and functional reorganization of contralateral hippocampus after temporal lobe epilepsy surgery

open access: yesNeuroImage: Clinical, 2021
Objective: To explore the structural and functional reorganization of contralateral hippocampus in patients with unilateral mesial temporal lobe epilepsy (mTLE) who achieved seizure-freedom after anterior temporal lobectomy (ATL).
Wei Li   +11 more
doaj   +1 more source

Gamma radiation-induced impairment of hippocampal neurogenesis, comparison of single and fractionated dose regimens Deterioro de la neurogénesis en el hipocampo inducida por radiación gamma, comparación de los regímenes de dosis única y fraccionada [PDF]

open access: yes, 2012
Radiation therapy of the brain is associated with many consequences, including cognitive disorders. Pathogenesis of radiation induced cognitive disorder is not clear, but reduction of neurogenesis in hippocampus may be an underlying reason. 24 adult male
Azami, N.S.   +2 more
core  

Automatic cell segmentation by adaptive thresholding (ACSAT) for large-scale calcium imaging datasets [PDF]

open access: yes, 2018
Advances in calcium imaging have made it possible to record from an increasingly larger number of neurons simultaneously. Neuroscientists can now routinely image hundreds to thousands of individual neurons.
Gritton, Howard J.   +6 more
core   +1 more source

The hippocampus and depression

open access: yesEuropean Psychiatry, 2002
SummaryThe effect of depression on the hippocampus has become the focus of a number of structural and functional neuroimaging studies. In the past two decades, advances in neuroimaging techniques now allow the examination of subtle changes in both regional structure and function that are associated with the pathophysiology of depression.
M.A Mintun, Y.I Sheline, B.L Mittler
openaire   +3 more sources

Longitudinal Relationship Between Pain and Depression in People With Inflammatory Arthritis: A Narrative Review

open access: yesArthritis Care &Research, EarlyView.
As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Comorbid depression is prevalent in adults with IA, affecting 15% to 39% of people. Although pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox   +3 more
wiley   +1 more source

May we routinely spare hippocampal region in primary central nervous system lymphoma during whole brain radiotherapy?

open access: yesRadiation Oncology, 2023
Purpose One of the main limiting factors of whole-brain radiation therapy (WBRT) for primary central nervous system lymphoma (PCNSL) is the impairment of neurocognitive functions (NCFs), which is mainly caused by radiation-induced injury to the ...
Ciro Mazzarella   +20 more
doaj   +1 more source

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