BMC Genomics, 2020 Background Salivary cell secretion (SCS) plays a critical role in blood feeding by medicinal leeches, making them of use for certain medical purposes even today.
Vladislav V. Babenko +23 more
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Identification, screening, and comprehensive evaluation of novel thrombin inhibitory peptides from the hirudo produced using pepsin [PDF]
Frontiers in PharmacologyPurposeThe inhibition of thrombin has proven to be an efficacious therapeutic approach for managing cardiovascular disease (CVD), with widespread implementation in clinical settings.
Xiaoyu Chai +12 more
doaj +2 more sources
Characterization of a Fatty Acid Amide Hydrolase (FAAH) in Hirudo Verbana. [PDF]
Neurochem ResThe endocannabinoid system plays a critical role in modulating both peripheral and central nervous system function. Despite being present throughout the animal kingdom, there has been relatively little investigation of the endocannabinoid system beyond ...
Kabeiseman E, Paulsen RT, Burrell BD.
europepmc +2 more sources
Identification and characterization of hirudin-HN, a new thrombin inhibitor, from the salivary glands of Hirudo nipponia [PDF]
PeerJ, 2019 Transcriptome sequencing data (6.5 Gb) of the salivary glands of the haematophagous leech Hirudo nipponia was obtained by using the BGIseq-500 platform.
Boxing Cheng +6 more
doaj +3 more sources
Comparative genomics suggests extensive antithrombotic gene expansion in Haemadipsa yanyuanensis [PDF]
BMC GenomicsHaemadipsa yanyuanensis Liu & Song, 1977, is a terrestrial blood-feeding leech whose antithrombotic repertoire remains insufficiently characterized. We present its first chromosome-level genome assembly (165.32 Mb across nine chromosomes; BUSCO: 97.6 ...
Yiquan Lin +8 more
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A Comprehensive Quality Evaluation System for Medicinal Leeches by Integrating Macromolecular Protein Analysis and Small-Molecule Marker Detection as Well as Quantitative Bioassays [PDF]
PharmaceuticalsBackground/Objectives: Medical leech (Hirudo in the Chinese Pharmacopoeia) is renowned in traditional medicine for its significant antithrombin activity. As an animal-derived medicine with complex and incompletely understood composition, its insufficient
Wenduan Wang +7 more
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Türkiye Parazitoloji Dergisi, 2019 Objective:The aim of this study was to investigate the internal and external morphological structures of two species of medicinal leeches (Hirudo sulukii and Hirudo verbana).Methods:Leech specimens were collected from various regions of Turkey between ...
Naim Sağlam
doaj +2 more sources
ERGA-BGE reference genome of Hirudo verbana, a once neglected freshwater haematophagous European medicinal leech [version 2; peer review: 2 approved] [PDF]
Open Research EuropeHirudo verbana Carena, 1820, commonly known as the southern medicinal leech, is one of several European medicinal leeches, whose full diversity has just recently started to be uncovered.
Jonathan M.D. Wood +14 more
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Viruses, 2013 Giant viruses and amoebae are common in freshwater, where they can coexist with other living multicellular organisms. We screened leeches from the species Hirudo medicinalis for giant viruses. We analyzed five H. medicinalis obtained from Tunisia (3) and
Philippe Colson +2 more
exaly +3 more sources
Unraveling the structure, chemical composition, and conserved signaling in leech teeth [PDF]
Animal Cells and SystemsUnlike vertebrates, the number of toothed taxa in invertebrates is very few, with leeches being the only tooth-bearing organisms in the phylum Annelida.
Yam Prasad Aryal +9 more
doaj +2 more sources