Serotonin modulates muscle function in the medicinal leech Hirudo verbana. [PDF]
Biol Lett, 2011 The body wall muscles of sanguivorous leeches power mechanically diverse behaviours: suction feeding, crawling and swimming. These require longitudinal muscle to exert force over an extremely large length range, from 145 to 46 per cent of the mean segmental swimming length.
Gerry SP, Ellerby DJ.
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Türkiye Parazitoloji DergisiObjective: This study aimed to investigate the histological and morphological differences between healthy and deformed specimens of the medicinal leech Hirudo verbana, with particular focus on tissue integrity and cellular organization.
Halime Tozak Yıldız +5 more
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Nanostructured Scaffold, Combined with Human Dental Pulp Stem Cell Secretome, Induces Vascularization in Medicinal Leech Model. [PDF]
Micromachines (Basel)As life expectancy continues to increase, age-related disorders are becoming more prevalent. Among these, vascular complications resulting from chronic inflammation are particularly concerning, as they impair angiogenesis and hinder tissue repair, both ...
Marcolli G +8 more
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Injury alters sensory, motor, and integrative elements underlying operant conditioning in the medicinal leech. [PDF]
PLoS OneStudies of pain/nociception often rely on simple reflexes to assess pain-related changes in behavior. However, there is considerable interest in utilizing more complex, self-initiated behaviors in place of stimulus-evoked reflexes.
Dockendorf ER, Burrell BD.
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May salivary gland secretory proteins from hematophagous leeches (Hirudo verbana) reach pharmacologically relevant concentrations in the vertebrate host? [PDF]
PLoS One, 2013 Saliva of hematophagous leeches (Hirudo sp.) contains bioactive proteins which allow the leech proper feeding and storage of ingested blood, but may also exert effects in the host.
Lemke S +4 more
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Investigating the Therapeutic Potential of Crude Leech Saliva Based on Its Anticancer, Antioxidant, and Anti-Inflammatory Effects. [PDF]
Curr Issues Mol BiolLeech therapy is a biotherapeutic approach that has been traditionally used for centuries and is currently being re-evaluated in modern medicine. The efficacy of this treatment is attributed to various bioactive compounds found in leech saliva, which ...
Bilden A +6 more
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In vivo efficacy of current stimuli computed by optimal tracking of neuron membrane voltage. [PDF]
PLoS OneWe describe an application of optimal control theory to in vivo intracellular stimulation of pressure-sensitive mechanosensory (P-cell) neurons of the leech Hirudo verbana.
Ferguson AC +5 more
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Functional morphology of suction discs and attachment performance of the Mediterranean medicinal leech (Hirudo verbanaCarena) [PDF]
Journal of the Royal Society Interface, 2016 Simon Poppinga +2 more
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Tissue regenerative potential of human dental pulp mesenchymal stem cell conditioned medium in wound healing of the medicinal leech. [PDF]
Stem Cell Res TherBackground As life expectancy increases, so does the incidence of age-related disorders, including vascular diseases and chronic wounds. These conditions are often associated with impaired angiogenesis and tissue repair, posing significant clinical ...
Marcolli G +11 more
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Biology, 2021 Until the beginning of the 21st century, the famous medicinal leech was thought to be represented by only one species, Hirudo medicinalis. However, recent publications have demonstrated that under that name, at least five different species of medicinal ...
Andrés Arias +5 more
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