Results 211 to 220 of about 288,678 (341)

The human photosensitive epilepsy model for clinical proof‐of‐principle trials of novel antiseizure medications: 2. Analysis of drug trials and predictive value of the model

open access: yesEpilepsia, EarlyView.
Abstract Clinical development of novel antiseizure medications (ASMs) would benefit from an early proof of principle (POP) model. The photosensitivity model, which uses the photoparoxysmal electroencephalographic response (PPR) as a surrogate of seizures, is currently the only human model that allows POP trials of investigational compounds after a ...
Wolfgang Löscher   +1 more
wiley   +1 more source

Investigation of the Pathomechanism of Chronic Cough Using an In Vitro Approach

open access: yes
Clinical &Experimental Allergy, Volume 55, Issue 3, Page 247-249, March 2025.
Umesh Singh, Jonathan A. Bernstein
wiley   +1 more source

Stress exposure in the mdx mouse model of Duchenne muscular dystrophy provokes a widespread metabolic response

open access: yesThe FEBS Journal, EarlyView.
A targeted mass spectrometry‐based metabolomics assay was conducted to identify the impact of stress exposure on the regulation of biological stress pathways in the mdx mouse model of Duchenne muscular dystrophy. We demonstrated a broad shift in the circulating stress‐relevant plasma metabolome associated with stressful scruff handling that was ...
Erynn E. Johnson, James M. Ervasti
wiley   +1 more source

Wakefulness is governed by GABA and histamine co-transmission [PDF]

open access: yes, 2015
Brickley, SG   +12 more
core   +1 more source

Elevated butyric acid and histamine in feces and serum as an indicator of onset of necrotic enteritis in broiler chickens. [PDF]

open access: yesFront Microbiol
Gautam H   +9 more
europepmc   +1 more source

Protective effects of Paeonia suffruticosa callus extract in skin through anti‐inflammation and repair UVB‐induced damage

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Peony callus extract (PCE) is beneficial for skin anti‐ageing and sensitivity induced by UVB radiation, through decreasing the level of inflammatory factors and matrix metalloproteinases. Furthermore, our research indicates that PCE effectively improves the total collagen content in human skin. Abstract Objective The study investigated effects of peony
Yufan Li   +9 more
wiley   +1 more source

Very Long‐Term Stability of Tryptase in Frozen Serum Samples

open access: yes
Clinical &Experimental Allergy, Volume 55, Issue 3, Page 276-277, March 2025.
Florent Broussal   +7 more
wiley   +1 more source

n‐3 PUFAs docosahexaenoic acid and eicosapentaenoic acid are effective natural pro‐resolution ingredients for topical skin applications

open access: yesInternational Journal of Cosmetic Science, EarlyView.
Skin encounters many challenges that lead to an inflammatory response. Resolution of this inflammation is needed to return the skin to a healthy state. A review of the role of topical n‐3 PUFAs, particularly DHA and EPA, in resolving skin inflammation and promoting skin health is presented.
John Nip   +2 more
wiley   +1 more source

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