Results 201 to 210 of about 151,455 (301)

Investigation of the mechanisms and modulation of irinotecan‐induced emesis in Suncus murinus

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Irinotecan is a widely used chemotherapeutic agent that frequently causes nausea and emesis. Its emetic mechanism of action is poorly understood and the choice of drugs to reduce nausea and emesis is largely empirical. Experimental Approach Using Suncus murinus, we examined (i) the dose–response and temporal profile of ...
Zengbing Lu, Julia Y. H. Liu, Yasuhiro Nakagami, Zitong Li, Xiaofei Huang, Man P. Ngan, Dexuan Cui, John A. Rudd   +7 more
wiley   +1 more source

Cooperative mechanism of neurotransmitter recognition and transport by the human vesicular polyamine transporter. [PDF]

Nat Commun
Guo Y, Yang G, Chai J, Shanklin J, Liu B, Lu M.   +5 more
europepmc   +1 more source

The fight of innate immunity and abnormal cannabinoids against Candida infection

British Journal of Pharmacology, EarlyView.
Candida species represent the most clinically significant fungal pathogens in humans, with invasive candidiasis carrying a mortality of 30%–40% in critically ill patients despite modern antifungal therapy. The innate immune system – through the coordinated and specific activities of neutrophils, macrophages, NK cells, mast cells and eosinophils ...
Prince Ofori, Ilan Zaffran, Francesca Levi Schaffer   +2 more
wiley   +1 more source

Sodium polyphosphate, a new drug for treatment of atopic dermatitis: basic considerations and clinical case studies.

Biomater Sci
Neufurth M, Nassabi H, Perovic-Ottstadt S, Dobmeyer R, Muñoz-Espí R, Ushijima H, Schröder HC, Wu C, Wang X, Müller WEG.   +9 more
europepmc   +1 more source

Spinal Mechanisms of Testosterone Involved in Itch Regulation. [PDF]

CNS Neurosci Ther
Chen L, Wang X, Cheng L, Li P, Wu Z, Li H.   +5 more
europepmc   +1 more source

ATRACURIUM AND HISTAMINE

British Journal of Anaesthesia, 1992
openaire   +2 more sources

The Serotonergic and Cholinergic Signaling Pathways Drive Gastric Precancerous Lesions and Its Potential Mechanism

Cancer Science, EarlyView.
Vagal cholinergic neurons promote gastric 5‐HT secretion, which drives gastric precancerous lesions through 5‐HTR1D and TRPV4, highlighting these as candidate targets for early intervention. ABSTRACT Gastric cancer (GC) is a leading lethal malignancy globally. Gastric precancerous lesion (GPL) represents a critical step in GC, but its neural regulatory
Shengli Gao, Xufei Feng, Nana Zhang, Jia Su, Yuyan Wang, Linghan Kong, Jianing Zhou, Hui Dong, Feifei Guo   +8 more
wiley   +1 more source

Anti-Allergic Potentials of Actinodaphne angustifolia: Integrated In Vivo Evaluation and In Silico Analysis of Bioactive Compounds. [PDF]

Chem Biodivers
Acharyya RN, Risha MAM, Rini NDW, Manandhar S, Shahi S, Bhadra BN, Das AK, Ariga K, Dev S, Shrestha LK.   +9 more
europepmc   +1 more source

Serum diamine oxidase levels in allergic asthma and/or allergic rhinitis: A cross-sectional study. [PDF]

Medicine (Baltimore)
Keskinel I, Eryilmaz M, Akkaya Firat A.
europepmc   +1 more source