Results 181 to 190 of about 151,455 (301)

<i>In vivo</i> porcine multi-omics integration identifies microbiome-driven histamine elevation and lasting gut perturbations following <i>Ascaris suum</i> infection and fenbendazole treatment. [PDF]

Virulence
Liu F, Streett H, Solano-Aguilar G, Smith AD, Carbaugh D, Urban JF, Li RW.   +6 more
europepmc   +1 more source

Need to Assess On‐Demand Versus Continuous Treatment in Allergic Rhinitis in ARIA‐EAACI Guidelines

Allergy, EarlyView.
Jean Bousquet, Bernardo Sousa‐Pinto, Maria J. Torres, Mario Morais‐Almeida, Ludger Klimek, Giorgio Ciprandi, Robert Naclerio, Torsten Zuberbier   +7 more
wiley   +1 more source

Alkalinised lidocaine as an anaesthetic before onabotulinumtoxinA injections. a randomised trial

BJU International, Volume 135, Issue 4, Page 638-647, April 2025.
Objectives To evaluate the effect of intravesical alkalinised lidocaine as an anaesthetic treatment on procedural pain during intradetrusor onabotulinumtoxinA (BTX‐A) injections for overactive bladder. Patients and Methods This single‐centre, randomised, double‐blind, placebo‐controlled two period crossover trial was conducted on women scheduled for ...
Meryam El Issaoui, Marlene Elmelund, Niels Klarskov   +2 more
wiley   +1 more source

Preliminary Kinetic Assessment of Quality Deterioration and Shelf-Life Estimation in Yellowfin Tuna Under Different Constant Storage Temperatures. [PDF]

Foods
Deng J, Chen T, Huang J, Li C, Hu X, Zhao X, Wu Y, Chen S, Zhao Y.   +8 more
europepmc   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

The Mechanism of Whey Protein Hydrolysates with Oral Immunotolerance. [PDF]

Int J Mol Sci
Wang MY, An PM, Mao L, Zhao WX, Cong YJ.
europepmc   +1 more source

Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders

British Journal of Pharmacology, EarlyView.
Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman, Christopher J. Black, Andrea Shin, Daniel Keszthelyi   +3 more
wiley   +1 more source

Frequency of Local Allergic Asthma in Bronchial Asthma Patients: Role of Conjunctival Challenge and Neutrophil Histamine Release. [PDF]

Cells
López-Postigo A, Vega-Rioja A, Rodríguez-Neira C, Monteseirín J.   +3 more
europepmc   +1 more source

Neuronal and ion channel mechanisms of noxious heat sensing in mammals: A puzzle of sensory physiology and pharmacology

British Journal of Pharmacology, EarlyView.
Transient receptor potential vanilloid 1 (TRPV1) was the first noxious heat‐sensitive channel discovered. In rodents, its role is robust in the heat response of the cell body of polymodal nociceptors, but surprisingly small in that of the peripheral terminals in the skin.
Gábor Pethő, Peter W. Reeh
wiley   +1 more source

Elevated Histamine Receptor 2 and Toll-Like Receptor 7 Expression in Rheumatoid Arthritis: Insights Into Inflammatory Mechanisms and Potential Therapeutic Strategies. [PDF]

Int J Rheum Dis
Kamil Al-Basri A, Sedighi S, Bagheri Y, Saghaiyan Jazi M, Heydari E, Azimi H, Davoodi H.   +6 more
europepmc   +1 more source