Results 211 to 220 of about 147,109 (307)

Agonists for the histamine H3 receptor differ in their gastroprotective activity in the rat

, 2001
GRANDI, Daniela, TIMMERMAN H., SCHUNACK W., MORINI, Giuseppina   +3 more
core  

CD93—An emerging vascular target in cancer therapy

British Journal of Pharmacology, EarlyView.
Abstract CD93 is a single‐pass transmembrane glycoprotein that belongs to the C‐type lectin domain group XIV family of proteins. Although it is known to be expressed in other cell types, namely, in some subsets of immune cells, CD93 is primarily expressed on endothelial cells, where it acts as a crucial regulator of angiogenesis.
Beatriz de Alves Pereira, Stefano Barbera, Roberta Lugano, Anna Dimberg   +3 more
wiley   +1 more source

OptoH₃R fusion protein mimics β-arrestin-mediated membrane endocytosis of histamine H₃ receptor in vitro. [PDF]

Mol Brain
Deng S, Zhou Z, Chen Z, Zheng Y, Zhou J.
europepmc   +1 more source

Immunolocalization of histamine H3 receptor in the rat gastrointestinal tract

, 2006
SHENTON F. C., GRANDI, Daniela, SCHUNACK W., MORINI, Giuseppina, CHAZOT P.   +4 more
core  

Systematic profiling reveals broad G protein coupling and context‐dependent modulation of cyclic AMP by the orphan receptor GPR139

British Journal of Pharmacology, EarlyView.
Background and Purpose G protein‐coupled receptors (GPCRs) are major drug targets, yet many orphan receptors remain poorly characterized. GPR139 has been implicated in CNS disorders, including schizophrenia and depression, but its signalling mechanisms remain unclear.
Boris Trapkov, Hans Bräuner, Alexander Sebastian Hauser   +2 more
wiley   +1 more source

Brucellar spondylitis is associated with disturbance in gut microbiota and histamine metabolism associated inflammation. [PDF]

Front Cell Infect Microbiol
Ma Z, Bai X, Tian J, Yao C, Yan Z, Ma X, Zhang C, Ma J, Lin Y, Zhang X, Wang H.   +10 more
europepmc   +1 more source

The H4 histamine receptor is expressed in both the human CNS and rodent PNS

, 2007
SHENTON F. C., GRANDI, Daniela, CHAZOT P. L., WALDVOGEL H., MORINI, Giuseppina   +4 more
core  

The ongoing oleoylethanolamide story: Therapeutic implications in the control of obesity and its comorbidities

British Journal of Pharmacology, EarlyView.
The global burden of obesity continues to rise, demanding effective pharmacological strategies for individuals in whom prevention alone is insufficient. Recent incretin‐based and multi‐agonist therapies have delivered unprecedented weight loss, demonstrating that the simultaneous modulation of multiple metabolic pathways can optimize body weight ...
Marzia Friuli, Alessia Campagna, Barbara Eramo, Christian Sepe, Annarita Zuena, Silvana Gaetani, Adele Romano   +6 more
wiley   +1 more source

Beyond Histamine: Mast Cell-Neuron Communication in Chronic Pruritic and Pain Disorders. [PDF]

Exp Dermatol
Kagan T, Yosipovitch G.
europepmc   +1 more source

Sodium polyphosphate, a new drug for treatment of atopic dermatitis: basic considerations and clinical case studies.

Biomater Sci
Neufurth M, Nassabi H, Perovic-Ottstadt S, Dobmeyer R, Muñoz-Espí R, Ushijima H, Schröder HC, Wu C, Wang X, Müller WEG.   +9 more
europepmc   +1 more source