Results 21 to 30 of about 341,151 (335)
Function and Role of Histamine H1 Receptor in the Mammalian Heart
Pharmaceuticals, 2023 Histamine can change the force of cardiac contraction and alter the beating rate in mammals, including humans. However, striking species and regional differences have been observed. Depending on the species and the cardiac region (atrium versus ventricle)
Joachim Neumann +4 more
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Histamine stimulates the proliferation of small and large cholangiocytes by activation of both IP3/Ca2+ and cAMP-dependent signaling mechanisms [PDF]
, 2012 Although large cholangiocytes exert their functions by activation of cyclic adenosine 3',5'-monophosphate (cAMP), Ca(2+)-dependent signaling regulates the function of small cholangiocytes. Histamine interacts with four receptors, H1-H4HRs.
Fanyin Meng +15 more
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Frontiers in Immunology, 2018 Histamine and its receptors (H1R–H4R) play a crucial and significant role in the development of various allergic diseases. Mast cells are multifunctional bone marrow-derived tissue-dwelling cells that are the major producer of histamine in the body.
E. Thangam +7 more
semanticscholar +1 more source
Role of Histamine in Modulating the Immune Response and Inflammation
Mediators of Inflammation, 2018 Inflammatory mediators, including cytokines, histamine, bradykinin, prostaglandins, and leukotrienes, impact the immune system, usually as proinflammatory factors.
A. Branco +3 more
semanticscholar +1 more source
Histamine can be Formed and Degraded in the Human and Mouse Heart
Frontiers in Pharmacology, 2021 Histamine is metabolized by several enzymes in vitro and in vivo. The relevance of this metabolism in the mammalian heart in vivo is unclear. However, histamine can exert positive inotropic effects (PIE) and positive chronotropic effects (PCE) in humans ...
Joachim Neumann +12 more
doaj +1 more source
Granuloma pouch and skin histamine of the rat [PDF]
, 1958 Using the granuloma pouch technique of SELYE, effect of modification in local histamine on the inflammatory tissue reactions was examined in rats. The increase in the weight of pouch wall and histological inflammatory changes were distinctly inhibited in
Irino, Shozo
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Slovenian Veterinary Research, 2023 Histamine is the biogenic amine responsible for scombroid poisoning in various types of fish and fish products. The study evaluated histamine content and bacteriological quality of salted and freeze sardine samples.
Maged Mostafa Mahmoud +3 more
doaj +1 more source
Acta Dermato-Venereologica, 2020 Psoriasis is a chronic inflammatory skin disorder characterized by hyperproliferative keratinocytes and immune cell infiltration into the skin, often accompanied by itch.
Kristine Rossbach +10 more
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Molecular Regulation of Histamine Synthesis [PDF]
Frontiers in Immunology, 2018 Histamine is a critical mediator of IgE/mast cell-mediated anaphylaxis, a neurotransmitter and a regulator of gastric acid secretion. Histamine is a monoamine synthesized from the amino acid histidine through a reaction catalyzed by the enzyme histidine ...
Hua Huang +3 more
semanticscholar +1 more source
Journal of Pharmacological Sciences, 2006 .: Accumulating evidence has highlighted the importance of histamine in immune responses. The H1 receptor is involved not only in allergic inflammatory reactions but also in augmentation of helper T cell (Th)1 responses, whereas H2 receptor suppresses Th
Tanaka Satoshi, Ichikawa Atsushi
doaj +1 more source