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Functional Diversity of Histamine and Histamine Receptors
In order to analyze the mechanisms by which a single biogenic amine like histamine is capable of inducing a wide variety of both physiologic and pathologic functions in various tissues/cells, histamine responses were dissected in detail from a biochemical and pharmacologic point of view.
Mitsuhashi, Masato, Payan, Donald G
openaire +2 more sources
Investigations on neuropeptide Y and histamine receptors by fluorescence-based and radiochemical methods [PDF]
In the last three decades, a large amount of experimental data (for example Förster resonance energy transfer (FRET) at fluorescently labelled receptors) supported the hypothesis of the dimerization of G-protein-coupled receptors (GPCR), including ...
Lopuch, Miroslaw
core +1 more source
Inspired by metal‐free carbonic anhydrases (CAs) that achieve efficient catalysis without metal cofactors, we herein report a sequence‐defined supramolecular peptoid platform that mimics metal‐free CAs and exhibits hydrolytic activity via a supramolecular assembly‐mediated proton‐transfer mechanism.
Progyateg Chakma +8 more
wiley +1 more source
Histamine and motivation [PDF]
Brain histamine may affect a variety of different behavioral and physiological functions; however, its role in promoting wakefulness has overshadowed its other important functions. Here, we review evidence indicating that brain histamine plays a central role in motivation and emphasize its differential involvement in the appetitive and consummatory ...
Torrealba, Fernando +3 more
openaire +3 more sources
好塩基球からのヒスタミン遊離に関する研究. 1 自動分析装置による全血からのヒスタミン遊離の測定 [PDF]
Histamine released from whole blood was determined by an automated fiuorometric histamine analysis system. The increased release of histamine from basophils by anti-IgE was observed in ten healthy subjects and 12 extrinsic asthma patients, while the ...
Tanizaki, Yoshiro +9 more
core +1 more source
ABSTRACT Gonadotropin‐inhibitory hormone (GnIH, also known as RFamide‐related peptide‐3, RFRP‐3) is a hypothalamic neuropeptide that regulates vertebrate reproduction via its receptor GPR147. Although GnIH is known to mediate stress‐induced reproductive suppression, its role in broader stress responses remains unclear.
Jiani Zhang +18 more
wiley +1 more source
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib +8 more
wiley +1 more source
Determining the Amount of Histamine Levels in Canned Tuna Fish Marketed in Supermarkets of Tabriz City [PDF]
Background & Objective: Histamine poisoning which is induced from seafood is the most common disease around the world. Determining the amount of histamine in canned tuna fish shows not only the healthy quality of fish, but also it is effective in ...
Javad Mohtadi nia +4 more
doaj +2 more sources
Histamine Induces Vascular Hyperpermeability by Increasing Blood Flow and Endothelial Barrier Disruption In Vivo. [PDF]
Histamine is a mediator of allergic inflammation released mainly from mast cells. Although histamine strongly increases vascular permeability, its precise mechanism under in vivo situation remains unknown.
Kohei Ashina +7 more
doaj +1 more source
Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia
The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian +12 more
wiley +1 more source

