Results 41 to 50 of about 146,548 (306)

Novel chalcone-based fluorescent human histamine H 3 receptor ligands as pharmacological tools [PDF]

open access: yes, 2012
Novel fluorescent chalcone-based ligands at human histamine H(3) receptors (hH(3)R) have been designed, synthesized, and characterized. Compounds described are non-imidazole analogs of ciproxifan with a tetralone motif.
Miriam Tomasch   +7 more
core   +1 more source

Seafood histamine intervention to alcohol intake: regulation, metabolism and control

open access: yesHuman, Health and Halal Metrics, 2020
Background and objective: Seafood have high nutritional value since they contain sufficient amounts of protein, lipid, micronutrients and long-chain polyunsaturated fatty acids, especially omega3 fatty acid.
Leila Peivasteh-Roudsari
doaj   +1 more source

High-Affinity Chemotaxis to Histamine Mediated by the TlpQ Chemoreceptor of the Human Pathogen Pseudomonas aeruginosa

open access: yesmBio, 2018
Histamine is a key biological signaling molecule. It acts as a neurotransmitter in the central and peripheral nervous systems and coordinates local inflammatory responses by modulating the activity of different immune cells. During inflammatory processes,
Andrés Corral-Lugo   +10 more
doaj   +1 more source

Histamine and Its Receptors in the Mammalian Inner Ear: A Scoping Review

open access: yesBrain Sciences, 2023
Background: Histamine is a widely distributed biogenic amine with multiple biological functions mediated by specific receptors that determine the local effects of histamine.
Lingyi Kong   +2 more
doaj   +1 more source

The Affinity of Histamine for Gq Protein-Coupled Histamine H1-Receptors Is Predominantly Regulated by Their Internalization in Human Astrocytoma Cells

open access: yesJournal of Pharmacological Sciences, 2012
We examined the regulatory mechanisms of the affinity of Gq protein-coupled histamine H1-receptors for histamine after histamine pretreatment in intact human U373 MG astrocytoma cells.
Shigeru Hishinuma   +3 more
doaj   +1 more source

The Roles of Cardiovascular H2-Histamine Receptors Under Normal and Pathophysiological Conditions

open access: yesFrontiers in Pharmacology, 2021
This review addresses pharmacological, structural and functional relationships among H2-histamine receptors and H1-histamine receptors in the mammalian heart.
Joachim Neumann   +4 more
doaj   +1 more source

Investigations on neuropeptide Y and histamine receptors by fluorescence-based and radiochemical methods [PDF]

open access: yes, 2011
In the last three decades, a large amount of experimental data (for example Förster resonance energy transfer (FRET) at fluorescently labelled receptors) supported the hypothesis of the dimerization of G-protein-coupled receptors (GPCR), including ...
Lopuch, Miroslaw
core   +1 more source

Histamine: a new immunomodulatory player in the neuron-glia crosstalk

open access: yesFrontiers in Cellular Neuroscience, 2014
Histamine is an amine acting as a major peripheral inflammatory mediator. In the brain, histamine was initially viewed as a neurotransmitter, but new evidences support its involvement in the modulation of innate immune responses. Recently, we showed that
Sandra M Rocha   +4 more
doaj   +1 more source

Molecular analysis of the histamine H3-receptor [PDF]

open access: yes, 2010
The histamine H3 receptor (H3R) is a biogenic amine receptor that belongs to family I of G protein-coupled receptors (GPCRs). During the past two decades, the H3R has gained much interest in academia and industry.
Schnell, David
core   +1 more source

Development of Histamine in Fresh and Canned Tuna Steaks Stored under Different Experimental Temperature Conditions

open access: yesFoods, 2022
Among biogenic amines, histamine is most frequently involved in foodborne intoxication. To evaluate histamine formation in tuna, several storage conditions were reproduced. An LC-MS/MS method was used for analytical determinations.
Alberto Altafini   +5 more
doaj   +1 more source

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