Results 51 to 60 of about 133,295 (311)

Histamine plasma levels from dietary histidine/histamine intake correlate with CGRP in trigeminal tissues

The Journal of Headache and Pain
Background Trigeminal afferents innervating the meninges are likely involved in the generation of headaches and migraine. A major proportion of these afferents can release calcitonin gene-related peptide (CGRP) upon stimulation. Several substances, among
Fernando de Mora, Mária Dux, Birgit Vogler, Annette Kuhn, Jana Schramm, Karl Messlinger   +5 more
doaj   +1 more source

Histamine release after injection of benzodiazepines and of etomidate. A problem associated with the solvent propylene glycol (= Libération d'histamine après injection de benzodiazépines et d'étomidate. Rôle du solvant propylène-glycol)

, 1993
Many drugs, especially when given in rapid sequence can cause histamine release. Ten healthy volunteers were premedicated with diazepam 10 mg.70 kg-1 i.v. and lormetazepam 1 mg.70 kg-1 i.v., respectively, 30 min prior to etomidate 0.15 mg.kg-1 i.v.
Doenicke, A., Lorenz, Wilfried, Hoernecke, R., Nebauer, A. E., Mayer, M.   +4 more
core   +1 more source

Decoding Undesirable Inflammatory Responses of Nucleic Acid‐Delivering Lipid Nanoparticles

Advanced Science, EarlyView.
Lipid nanoparticles (LNPs) enable efficient nucleic acid delivery, but their immunogenicity is a double‐edged sword. This review explores LNP‐driven innate and adaptive immunity, covering lipid components, endosomal escape, and nucleic acid sensing.
Ruimin Hu, Yin Dou, Chenwen Li, Yuying Mu, Huiying Ouyang, Wenhao Shen, Jianxiang Zhang   +6 more
wiley   +1 more source

Progress in Allergy Signal Research on Mast Cells: The Role of Histamine in Immunological and Cardiovascular Disease and the Transporting System of Histamine in the Cell

Journal of Pharmacological Sciences, 2008
Since its discovery in 1910, histamine has been regarded as one of the most important biogenic amines in the medical and biological fields. This article summarizes the information about the role of histamine in allergic situations, atherosclerosis, and ...
Hiroshi Ohtsu
doaj   +1 more source

Histamine H3 and H4 receptors are expressed on distinct endocrine cell types in the rat fundic mucosa

, 2007
The present study was designed to explore the expression and distribution of histamine H3 and H4 receptors within the rat gastric fundus by immunohistochemistry using our unique immunological probes.
SHENTON F. C., GRANDI, Daniela, BECCHI, Gabriella, CHAZOT P. L., BECCHI G., SHENTON F., MORINI, Giuseppina, CHAZOT P.   +7 more
core   +1 more source

Study of Histamine Detection using Liquid Chromatography and Gas Chromatography [PDF]

, 2021
Histamine is a heterocyclic amine shaped by decarboxylation of the histidine. It is a compound that lack chromophore and involatile. However, the detection of histamine is imperative due to the characteristic of histamine has given several disadvantages ...
Muhammad Mukram, Mohamed Mackeen, Muhammad Abdurrahman, Munir, Khairiah Haji, Badri, Lee, Yook Heng   +3 more
core   +1 more source

Heterojunction‐Engineered Mass Spectrometry Platform for Deciphering Serum Metabolic Fingerprints in Diagnosis of Respiratory Diseases

Advanced Science, EarlyView.
Hollow Co3O4/TiO2 heterojunctions are engineered for high‐throughput laser desorption/ionization mass spectrometry. The built‐in electric field drives efficient charge separation and photothermal conversion, while the hierarchical mesoporous network enables robust salt and protein tolerance.
Junyu Chen, Chaoqi Wang, Xi Yu, Yuming Jiang, Yijiao Qu, Huihui Fu, Yuyin Bu, Xiaoyong Zhang, Zongxiu Nie   +8 more
wiley   +1 more source

Reprogramming the Immune Landscape of Inflammatory Breast Cancer

Advanced Science, EarlyView.
Inflammatory breast cancer is the most lethal subtype of breast cancer and is characterized by an immunosuppressive tumor microenvironment (TME) driven by a complex network of immune cells and inflammatory cytokines, contributing to its aggressiveness and treatment challenges. Immune checkpoint inhibitors, either alone or in combination, show potential
Verena Martinez‐Rodriguez, Suguru Ogata, Xiaoping Wang, Naoto T. Ueno   +3 more
wiley   +1 more source

Exogenous Histamine Stimulates Colorectal Cancer Implant Growth via Immunosuppression in Mice

Journal of Pharmacological Sciences, 2005
Results from a limited number of studies suggest a potential role for endogenous histamine in regulating tumor growth in immunocompetent cells. The present study examined the effects of exogenous histamine on colorectal cancer growth and the immune ...
Kazuyoshi Tomita, Susumu Okabe
doaj   +1 more source

Functional characterisation of the novel histamine H(3) receptor agonist, VUF 5810, on the guinea-pig isolated ileum

, 2003
It is known that the activation of prejunctionally-located histamine H3 receptors down-regulates the exocytotic acetylcholine release from the myenteric plexus and thus produces a negative control on the intestinal motility [1].
POZZOLI, Cristina, MENOZZI, Alessandro, KITBUNNADAJ R., TIMMERMANN H., LEURS R., TIMMERMAN H., POLI, Enzo, CORUZZI G.   +7 more
core   +1 more source