Results 51 to 60 of about 235,257 (355)
Molecular analysis of the histamine H3-receptor [PDF]
, 2010 The histamine H3 receptor (H3R) is a biogenic amine receptor that belongs to family I of G protein-coupled receptors (GPCRs). During the past two decades, the H3R has gained much interest in academia and industry.
Schnell, David
core +1 more source
Highly potent, selective acylguanidine-type histamine H2 receptor agonists: synthesis and structure-activity relationships [PDF]
, 2008 Potent and selective histamine H2 receptor (H2R) agonists are valuable pharmacological tools and might be of therapeutic value as drugs, for example in the treatment of severe congestive heart failure.
Kraus, Anja
core +1 more source
Histamine pharmacology: from Sir Henry Dale to the 21st century
British Journal of Pharmacology, 2018 Histamine has been one of the most studied substances in medicine, playing a major role in diverse (patho)physiological processes. It elicits its multifaceted modulatory functions by activating four types of GPCRs, designated as H1–4.
E. Tiligada, M. Ennis
semanticscholar +1 more source
Functional Diversity of Histamine and Histamine Receptors
Journal of Investigative Dermatology, 1992 In order to analyze the mechanisms by which a single biogenic amine like histamine is capable of inducing a wide variety of both physiologic and pathologic functions in various tissues/cells, histamine responses were dissected in detail from a biochemical and pharmacologic point of view.
Mitsuhashi, Masato, Payan, Donald G
openaire +2 more sources
Glutathione‐Responsive Acyl‐Modifications for Targeted RNA Decaging and Prolonged Protein Synthesis
Angewandte Chemie, EarlyView.The self‐immolation of disulfide‐based mRNA modifications in response to endogenous glutathione (GSH) promotes a gradual release of translatable mRNA within the cell, leading to improved nuclease resistance, tunable release properties, and a significant increase (up to 600%) of target protein production over time. This strategy offers an exciting proof
Mary E. Flood +6 more
wiley +2 more sources
Journal of Innate Immunity, 2022 We found that histamine (10−9 M) did not have any effect on the in vitro capture of Escherichia coli by neutrophils but accelerated its intracellular killing.
Karim Dib +5 more
doaj +1 more source
Histamine receptors and cancer pharmacology: an update
British Journal of Pharmacology, 2018 In the present review, we will discuss the recent advances in the understanding of the role of histamine and histamine receptors in cancer biology. The controversial role of the histaminergic system in different neoplasias including gastric, colorectal ...
N. Massari, Melisa B. Nicoud, V. Medina
semanticscholar +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
The Journal of Poultry Science, 2007 To implicate histamine and its receptors in feed intake and nutrient transport, White Leghorn cockerels of the same age and body weight were grouped randomly into six groups.
Abdul Nasir +2 more
doaj +1 more source
Histamine food poisonings: A systematic review and meta-analysis
Critical reviews in food science and nutrition, 2018 Objective: The aim of this study was to assess the mean of histamine concentration in food poisoning. Design: Systematic review and meta-analysis of reports published between 1959 and 2013.
F. Colombo +3 more
semanticscholar +1 more source