Results 51 to 60 of about 310,272 (392)

Ligand-guided homology modeling drives identification of novel histamine H3 receptor ligands [PDF]

open access: yes, 2019
In this study, we report a ligand-guided homology modeling approach allowing the analysis of relevant binding site residue conformations and the identification of two novel histamine H3 receptor ligands with binding affinity in the nanomolar range.
Hagenow, Stefanie   +3 more
core   +1 more source

Functional Diversity of Histamine and Histamine Receptors

open access: yesJournal of Investigative Dermatology, 1992
In order to analyze the mechanisms by which a single biogenic amine like histamine is capable of inducing a wide variety of both physiologic and pathologic functions in various tissues/cells, histamine responses were dissected in detail from a biochemical and pharmacologic point of view.
Donald G. Payan, Masato Mitsuhashi
openaire   +3 more sources

Nasal histamine responses in nonallergic rhinitis with eosinophilic syndrome [PDF]

open access: yes, 2015
Background: Nonallergic rhinitis with eosinophilic syndrome (NARES) is persistent, without atopy, but with ≥25% nasal eosinophilia. Hypereosinophilia seems to contribute to nasal mucosa dysfunction.
Ciofalo, Andrea   +7 more
core   +1 more source

Histamine receptors and cancer pharmacology: an update

open access: yesBritish Journal of Pharmacology, 2018
In the present review, we will discuss the recent advances in the understanding of the role of histamine and histamine receptors in cancer biology. The controversial role of the histaminergic system in different neoplasias including gastric, colorectal ...
N. Massari, Melisa B. Nicoud, V. Medina
semanticscholar   +1 more source

Obesity treatment initiation, retention, and outcomes in the Veterans Affairs MOVE! Program among rural and urban veterans

open access: yesObesity Science &Practice, Volume 8, Issue 6, Page 784-793, December 2022., 2022
Abstract Objective Rural veterans have high obesity rates. Yet, little is known about this population's engagement with the Veterans Affairs (VA) weight management program (MOVE!). The study objective is to determine whether MOVE! enrollment, anti‐obesity medication use, bariatric surgery use, retention, and outcomes differ by rurality for veterans ...
Kathleen M. Robinson   +6 more
wiley   +1 more source

Effects of Histamine and H1- and H2-Receptor Blocker on Food Intake, Food Passage Rate and in situ Nutrient Uptake from the Small Intestine of Chicken (Gallus domestics)

open access: yesThe Journal of Poultry Science, 2007
To implicate histamine and its receptors in feed intake and nutrient transport, White Leghorn cockerels of the same age and body weight were grouped randomly into six groups.
Abdul Nasir   +2 more
doaj   +1 more source

Platelet-Activating Factor-Induced Reduction in Contact Hypersensitivity Responses Is Mediated by Mast Cells via Cyclooxygenase-2-Dependent Mechanisms [PDF]

open access: yes, 2018
Platelet-activating factor (PAF) stimulates numerous cell types via activation of the G protein-coupled PAF receptor (PAFR). PAFR activation not only induces acute proinflammatory responses, but it also induces delayed systemic immunosuppressive effects ...
FitzGerald, Garret A.   +6 more
core   +1 more source

Biogenic Amines in Plant-Origin Foods: Are they Frequently Underestimated in Low-Histamine Diets?

open access: yesFoods, 2018
Low-histamine diets are currently used to reduce symptoms of histamine intolerance, a disorder in histamine homeostasis that increases plasma levels, mainly due to reduced diamine-oxidase (DAO) activity.
Sònia Sánchez-Pérez   +5 more
semanticscholar   +1 more source

Histamine: neural circuits and new medications

open access: yesSleep, 2018
Histamine was first identified in the brain about 50 years ago, but only in the last few years have researchers gained an understanding of how it regulates sleep/wake behavior.
T. Scammell   +4 more
semanticscholar   +1 more source

Sustainable Smart Packaging from Protein Nanofibrils

open access: yesAdvanced Materials, EarlyView.
Smart packaging can extend shelf life and improve food quality monitoring. This study introduces a novel smart packaging solution using amyloid fibrils and red radish anthocyanins to monitor seafood spoilage. These findings show that these films effectively indicate shrimp freshness and possess high antibacterial and antioxidant properties, offering a ...
Mohammad Peydayesh   +8 more
wiley   +1 more source

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