Results 51 to 60 of about 310,272 (392)
Ligand-guided homology modeling drives identification of novel histamine H3 receptor ligands [PDF]
In this study, we report a ligand-guided homology modeling approach allowing the analysis of relevant binding site residue conformations and the identification of two novel histamine H3 receptor ligands with binding affinity in the nanomolar range.
Hagenow, Stefanie+3 more
core +1 more source
Functional Diversity of Histamine and Histamine Receptors
In order to analyze the mechanisms by which a single biogenic amine like histamine is capable of inducing a wide variety of both physiologic and pathologic functions in various tissues/cells, histamine responses were dissected in detail from a biochemical and pharmacologic point of view.
Donald G. Payan, Masato Mitsuhashi
openaire +3 more sources
Nasal histamine responses in nonallergic rhinitis with eosinophilic syndrome [PDF]
Background: Nonallergic rhinitis with eosinophilic syndrome (NARES) is persistent, without atopy, but with ≥25% nasal eosinophilia. Hypereosinophilia seems to contribute to nasal mucosa dysfunction.
Ciofalo, Andrea+7 more
core +1 more source
Histamine receptors and cancer pharmacology: an update
In the present review, we will discuss the recent advances in the understanding of the role of histamine and histamine receptors in cancer biology. The controversial role of the histaminergic system in different neoplasias including gastric, colorectal ...
N. Massari, Melisa B. Nicoud, V. Medina
semanticscholar +1 more source
Abstract Objective Rural veterans have high obesity rates. Yet, little is known about this population's engagement with the Veterans Affairs (VA) weight management program (MOVE!). The study objective is to determine whether MOVE! enrollment, anti‐obesity medication use, bariatric surgery use, retention, and outcomes differ by rurality for veterans ...
Kathleen M. Robinson+6 more
wiley +1 more source
To implicate histamine and its receptors in feed intake and nutrient transport, White Leghorn cockerels of the same age and body weight were grouped randomly into six groups.
Abdul Nasir+2 more
doaj +1 more source
Platelet-Activating Factor-Induced Reduction in Contact Hypersensitivity Responses Is Mediated by Mast Cells via Cyclooxygenase-2-Dependent Mechanisms [PDF]
Platelet-activating factor (PAF) stimulates numerous cell types via activation of the G protein-coupled PAF receptor (PAFR). PAFR activation not only induces acute proinflammatory responses, but it also induces delayed systemic immunosuppressive effects ...
FitzGerald, Garret A.+6 more
core +1 more source
Biogenic Amines in Plant-Origin Foods: Are they Frequently Underestimated in Low-Histamine Diets?
Low-histamine diets are currently used to reduce symptoms of histamine intolerance, a disorder in histamine homeostasis that increases plasma levels, mainly due to reduced diamine-oxidase (DAO) activity.
Sònia Sánchez-Pérez+5 more
semanticscholar +1 more source
Histamine: neural circuits and new medications
Histamine was first identified in the brain about 50 years ago, but only in the last few years have researchers gained an understanding of how it regulates sleep/wake behavior.
T. Scammell+4 more
semanticscholar +1 more source
Sustainable Smart Packaging from Protein Nanofibrils
Smart packaging can extend shelf life and improve food quality monitoring. This study introduces a novel smart packaging solution using amyloid fibrils and red radish anthocyanins to monitor seafood spoilage. These findings show that these films effectively indicate shrimp freshness and possess high antibacterial and antioxidant properties, offering a ...
Mohammad Peydayesh+8 more
wiley +1 more source