Results 251 to 260 of about 53,301 (333)

Mast cell-neuron axis as a core mechanism in chronic pruritus of atopic dermatitis: from mechanistic insights to therapeutic targets. [PDF]

Front Immunol
Li D, Han Y, Zhou J, Yang H, Chen J, Tey HL, Tan TTY.   +6 more
europepmc   +1 more source

Stromal Cell‐Mast Cell Communication Orchestrates Anti‐Viral Immunity in the Meninges

Advanced Science, Volume 13, Issue 5, 27 January 2026.
This study delineates the spatial distribution and postnatal maturation of meningeal mast cells and uncovers their essential role in antiviral immunity. Using genetic models, mast cells are shown to promote CD8⁺ T cell infiltration and viral clearance via IL‐33 receptor signaling and synergistic activation by IL‐33 and ATP from infected stromal cells ...
Qingqing Li, Weijia Chen, Mengxue Sun, Xinbo Ni, Qishan Ran, Xiaoyu Hu, Fang Cao, Wenwen Zeng   +7 more
wiley   +1 more source

Emerging therapeutic approaches for treating abdominal pain. [PDF]

J Can Assoc Gastroenterol
Jimenez-Vargas NN, Parkar N, Takami K, Wood HM, Lomax AE, Reed DE, Vanner SJ.   +6 more
europepmc   +1 more source

Machine Learning Integration Framework Constructs a Lactylation‐Associated Gene Signature to Improve Prognosis in Bladder Cancer

Cancer Medicine, Volume 15, Issue 1, January 2026.
ABSTRACT Background Bladder cancer remains a significant challenge in oncology owing to its high recurrence rates and limited treatment options, particularly in cases of resistance to standard therapies. Aims Our study aimed to pinpoint a lactylation‐associated gene signature capable of predicting prognosis and providing important theoretical support ...
Jingsong Wang, Qianxue Lu, Panpan Jiao, Jun Jian, Qingyuan Zheng, Zhiyuan Chen, Xiuheng Liu, Shanshan Wan, Lei Wang   +8 more
wiley   +1 more source

Innate immunity in chemotherapy-induced peripheral neuropathy: recent advances. [PDF]

Front Pain Res (Lausanne)
Dong N, Lin T.
europepmc   +1 more source

Novel Tetrahydroquinazolinamines as Selective Histamine 3 Receptor Antagonists for the Treatment of Obesity

, 2019
Ajeet Kumar, Venkata Reddy Pasam, Ravi Thakur, Maninder Singh, Kartikey Singh, Mahendra Shukla, Anubhav Yadav, Shalini Dogra, Chandan Sona, Deepmala Umrao, Swati Jaiswal, Hafsa Ahmad, Mamunur Rashid, Sandeep Kumar Singh, Muhammad Wahajuddin, Anil Kumar Dwivedi, Mohammad Imran Siddiqi, Jawahar Lal, Rama P. Tripathi, Prem N. Yadav   +19 more
openalex   +1 more source

Acanthospermum hispidum and Its Metabolite Stigmasterol Modulates Anti‐Inflammatory Antagonism of COX‐1 and TGF‐β

Chemistry &Biodiversity, Volume 23, Issue 1, January 2026.
This study evaluates the anti‐inflammatory effect of Acanthospermum hispidum (AH) leaves and confirms its traditional use on diseases linked to inflammation. AH ethanol extract presents a dose‐dependent increase in anti‐inflammatory activity on the different times examined (T30 – T150). Also, stigmasterol present in AH shows potent antagonist influence
Onome Mary Adeboye, Abimbola Sowemimo, Muyiwa Samuel Fageyinbo, Oluwasegun Adedokun, Abdul Basit, Opeyemi Joshua Olatunji, Epole Ngolle Ntungwe   +6 more
wiley   +1 more source

Influenza a Virus Inhibition: Evaluating Computationally Identified Cyproheptadine Through In Vitro Assessment. [PDF]

Int J Mol Sci
Glisic S, Stevanovic K, Perdih A, Bukreyeva N, Maruyama J, Perovic V, López-Serrano S, Darji A, Radosevic D, Sencanski M, Veljkovic V, Botta B, Mori M, Paessler S.   +13 more
europepmc   +1 more source

T Cell/Mast Cell Crosstalk in the Skin of Patients Suffering From Immune‐Mediated Diseases, Focusing on Chronic Spontaneous Urticaria

Clinical and Translational Allergy, Volume 16, Issue 1, January 2026.
ABSTRACT The crosstalk between immune cells in skin lesions of numerous immune‐mediated diseases such as atopic dermatitis, psoriasis and other T cell mediated is fundamental for understanding the pathogenesis and treating these diseases. The mechanisms by which most activated immune cells such as T cells, mast cells, and neutrophils are shifted from ...
Elias Toubi, Raeda Mubariki, Zahava Vadasz   +2 more
wiley   +1 more source

Postoperative nausea and vomiting: translating pathophysiological mechanisms into clinical management. [PDF]

Perioper Med (Lond)
Zhao X, Liao W, Chen C, Zheng Y, Li L, Chang Q, Qiu L, Shen J.   +7 more
europepmc   +1 more source