Results 271 to 280 of about 53,301 (333)

Evaluation of the clinical application of histamine H2 receptor antagonists in the prevention of chemotherapy-induced nausea and vomiting based on the attribute hierarchy model method. [PDF]

Front Pharmacol
Song J, Liu L, Meng B, Zhao H, Zhang P, Chen H, Wang Y.   +6 more
europepmc   +1 more source

Acid Suppression in Mild‐Moderate Laryngomalacia Without GERD: A Randomized Controlled Trial

The Laryngoscope, Volume 136, Issue 1, Page 471-478, January 2026.
Infants ≤ 6 months old with mild to moderate laryngomalacia at a tertiary children's hospital were randomized to famotidine and feeding modifications (AST) or feeding modifications alone (no‐AST). Patients randomized to AST (n = 20) and no‐AST (n = 20) had comparable improvement on Laryngomalacia Airway Symptom Score and Infant Gastroesophageal Reflux ...
Amber D. Shaffer, Zainab Balogun, Allison B. J. Tobey, Raymond C. Maguire, Jeffrey P. Simons, Joseph E. Dohar, Jennifer L. Mccoy, Marina V. Rushchak, Reema Padia   +8 more
wiley   +1 more source

Current research hotspots and difficulties of chronic prostatitis/chronic pelvic pain syndrome: neuroendocrine mechanism. [PDF]

Ann Med
Shao B, Wu K, Fan Z, Gao X, Wan S, Xiao L, Zuo Y, Pi J, Sun P.   +8 more
europepmc   +1 more source

Role of Gynecologic Findings in Interstitial Cystitis/Bladder Pain Syndrome: A Consensus

Neurourology and Urodynamics, Volume 45, Issue 1, Page 39-45, January 2026.
ABSTRACT Objective To evaluate the role of gynecologic findings in Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) by reviewing current international guidelines and identifying relevant gynecologic co‐morbidities. Methods This consensus statement was developed through a systematic four‐phase process: (1) comprehensive literature review across ...
Marie E. Sullivan, Amr El Haraki, Anna Padoa, Katy Vincent, Kristene E. Whitmore, Mauro Cervigni   +5 more
wiley   +1 more source

Emerging Epigenetic Therapeutics and Diagnostics for Autism Spectrum Disorder. [PDF]

Curr Issues Mol Biol
Kao C, Lim KK, Chen ES.
europepmc   +1 more source

Development of Magnetic Nanoparticle‐Added Cryogel Membrane Materials for the Removal of Pharmaceutical Wastes

Natural Sciences, Volume 6, Issue 1, January 2026.
Magnetic mg‐Fe3O4‐APTES nanoparticle‐doped p(HEMA)‐phenylboronic acid cryogel membranes are developed for the efficient removal of dopamine from pharmaceutical wastewater. Utilizing boronate affinity interactions, the system demonstrates a high adsorption capacity of 1969.1 mg/g and eliminates 81.3% of the target molecule within 15 minutes.
Cansu İlke Kuru‐Sumer, Fulden Ulucan‐Karnak, Sinan Akgöl   +2 more
wiley   +1 more source

Piperazine Derivatives: A Privileged Scaffold in Modern Synthesis and Medicinal Chemistry

ChemistryOpen, Volume 15, Issue 1, January 2026.
Piperazine‐based bioactive molecules represent a versatile class of compounds with broad therapeutic potential. Structural modification of the piperazine scaffold governs key structure–activity relationships, enabling antibacterial, antifungal, antitumor, neuroactive, and anti‐inflammatory activities.
Assel Ten, Raushan Koizhaiganova, Dilnaz Bissenbay, Bagila Tursynova, Zhanar Zhaxibayeva, Valentina Yu   +5 more
wiley   +1 more source

Transient Receptor Potential (TRP) Channels as Fundamental Regulators of Fibrosis and Pruritus-A New Therapeutic Target for Pathological Scar Management. [PDF]

Int J Mol Sci
Tang Y, Zhang Z, Zhang Y.
europepmc   +1 more source

Activity‐restoring mutations in the histamine H3 receptor increase constitutive activity and reduce structural stability

Protein Science, Volume 35, Issue 1, January 2026.
Abstract The histamine H3 receptor (H3R) is a class A G protein‐coupled receptor (GPCR) that regulates neurotransmitter release in the central nervous system. Although structures of H3R in both inactive and active states have been elucidated, the functional roles of specific residues remain unclear.
Ami Nakajima, Hiroto Kaneko, Kosuke Oyama, Misumi Kuchiji, Ayane Itakura, Chiaki Arai, Mitsunori Shiroishi   +6 more
wiley   +1 more source

Histamine H1 receptor inverse agonists improve structure and pain in an osteoarthritis mouse model. [PDF]

J Clin Invest
Kurakazu I, Olmer M, Swahn H, Myers K, Kenvisay C, Akasaki Y, Nakashima Y, Lotz MK.   +7 more
europepmc   +1 more source