Results 41 to 50 of about 28,885 (301)

RELEASE OF HISTAMINE BY H2-RECEPTOR ANTAGONISTS [PDF]

The Lancet, 1982
letter
Parkin, J. V., Ackroyd, E. B., Glickman, S., Hobsley, M., Lorenz, Wilfried   +4 more
openaire   +3 more sources

Versatile Detection of Cellular Protein via Fluorescence Anisotropy

Advanced Science, EarlyView.
Cell Lysate Fluorescence Anisotropy (CFAST) utilizes long lifetime dye‐labeled nanobodies for rapid protein quantification in minimally purified, complex cell lysate. When coupled with cellular thermal shift, CFAST allows high‐throughput detection of endogenous protein‐small molecule engagement, facilitating the discovery of novel binders for ...
Qing Tang, Yuan‐Ping Wei, Ricky Ruiqi Ma, Na Wei, Tammy Zihan Zhou, Hilary Kung‐Yu Ho, Zafar Iqbal Bhat, Iqra Ishrat, Xiaoyu Li, Judy Wai Ping Yam, Yung Hou Wong, Qiankun Wang, Justin L. Tan   +12 more
wiley   +1 more source

Anti-KSHV activity of antagonists of histamine receptors. [PDF]

, 2019
Anti-KSHV activity of antagonists of histamine receptors.
Lu Dai (528895), Haiwei Zhang (223979), Wei Tang (53470), Zhiqiang Qin (66680), Jungang Chen (367400), Alana Goldstein (8067395), J. Craig Forrest (8067398), Xulin Chen (319560), Steven R. Post (7853858)   +8 more
core   +1 more source

Histamine release and fibrinogen adsorption mediate acute inflammatory responses to biomaterial implants in humans

Journal of Translational Medicine, 2007
Background Medical implants often fail as a result of so-called foreign body reactions during which inflammatory cells are recruited to implant surfaces.
Eaton John W, Zdolsek Johann, Tang Liping   +2 more
doaj   +1 more source

Nanomaterials for Allergy Diagnosis and Treatment: Advances, Opportunities and Translational Challenges

Advanced Science, EarlyView.
Nanomaterials offer dual applications in allergy management. For diagnosis, nanomaterials enhance analytical sensitivity and improve detection in specific IgE and functional assays such as the basophil activation test (BAT). For allergen‐specific immunotherapy, nanomaterials enable allergen masking and controlled release, and effectively modulate the ...
Madiha Habib, Shan Jiang, Joyce ZX Lee, CW Lim, HL Yeung, Nicki YH Leung, Patrick SC Leung, Ting F Leung, Christine YY Wai   +8 more
wiley   +1 more source

Novel Insight of Histamine and Its Receptor Ligands in Glaucoma and Retina Neuroprotection

Biomolecules, 2021
Glaucoma is a multifactorial neuropathy characterized by increased intraocular pressure (IOP), and it is the second leading cause of blindness worldwide after cataracts.
Silvia Sgambellone, Laura Lucarini, Cecilia Lanzi, Emanuela Masini   +3 more
doaj   +1 more source

Mucoadhesive Peptide‐Catalase Self‐Assembled Nano‐Formulation for Effective Treatment of Mucosal Inflammatory Diseases

Advanced Science, EarlyView.
CR8L10 is self‐assembled with catalase (CAT) to form CR8L10@CAT nanocomplexes, which can anchor to mucosal surfaces via thiol‐disulfide exchange with mucin, thereby enhancing their mucosal retention. The efficient reactive oxygen species (ROS) scavenging at inflamed sites would then result in successful treatment in both the intravesical IC/BPS model ...
Xinzhu Li, Yuxuan Ma, Di He, Yingying Huang, Yutong Jiang, He Zhao, Shengjie Ge, Ruirui Zhao, Hejia Yuan, Wendi Jiang, Wenjun Zhu, Kai Liu, Han Zhang, Zhuang Liu   +13 more
wiley   +1 more source

Potential immunological consequences of pharmacological suppression of gastric acid production in patients with multiple sclerosis

BMC Medicine, 2012
Corticosteroids are standard treatment for patients with multiple sclerosis experiencing acute relapse. Because dyspeptic pain is a common side effect of this intervention, patients can be given a histamine receptor-2 antagonist, proton pump inhibitor or
Biswas Sangita, Benedict Stephen H, Lynch Sharon G, LeVine Steven M   +3 more
doaj   +1 more source

Targeted β‐Glucan‐Veiled Oral Apremilast Nanotherapy Modulates Key Dysbiosis‐Associated Gut Microbiota and Alleviates Ulcerative Colitis‐Associated Anxiety, Depression, and Neuropsychiatric Behaviors

Advanced Science, EarlyView.
This study introduces β‐glucan‐shielded apremilast laden nanomicelles that withstand gastrointestinal degradation, selectively accumulate in inflamed colon tissue, and modulate the microbiota–gut–brain axis. The formulation restores barrier integrity, reduces systemic and neuroinflammation, and improves anxiety‐ and depression‐like behaviors in colitis
Chandrashekhar Jori, Ahmed Shaney Rehman, Taruna Lamba, Anas Ahmad, Jattin Kumar, Aneesh Ali, Ajesh Joshi, Ashraf Ali, Suhel Parvez, Javed N. Agrewala, Rehan Khan   +10 more
wiley   +1 more source

Synthesis and pharmacological identification of neutral histamine H1-receptor antagonists [PDF]

, 2003
In the present study we searched for neutral antagonists for the human histamine
Smit, Martine J., Smit, M.J.; id_orcid, Leurs, Rob, Smit, M.J., van de Wetering, I., van de Wetering, Ineke, Wetering, I. van de, Timmerman, H., Elz, S., Govoni, Marinella, Timmerman, Henk, Menge, Wiro M. B. P., Menge, W.M.P.B., Schunack, W., Elz, Sigurd, Bakker, Remko A., Schunack, Walter, Bakker, R.A., Govoni, M, Leurs, R.   +19 more
core   +1 more source