Results 111 to 120 of about 35,308 (311)

Histamine H1 Receptors in Neural Stem Cells Are Required for the Promotion of Neurogenesis Conferred by H3 Receptor Antagonism following Traumatic Brain Injury

Stem Cell Reports, 2019
Summary: The neurological recovery following traumatic brain injury (TBI) is limited, largely due to a deficiency in neurogenesis. The present study explores the effects of histamine H3 receptor (H3R) antagonism on TBI and mechanisms related to ...
Rujia Liao, Youchao Chen, Li Cheng, Lishi Fan, Han Chen, Yushan Wan, Yi You, Yanrong Zheng, Lei Jiang, Zhong Chen, Xiangnan Zhang, Weiwei Hu   +11 more
doaj  

Contribution of Histamine to Nociceptive Behaviors Induced by Intrathecally Administered Cholecystokinin-8

Frontiers in Pharmacology, 2020
The involvement of spinal release of histamine in the nociceptive behaviors induced by cholecystokinin-8 (CCK-8) was investigated in mice. Intrathecal (i.t.) injection of CCK-8 elicited the nociceptive behaviors consisting of biting and licking.
Takafumi Hayashi, Chizuko Watanabe, Soh Katsuyama, Yasuyuki Agatsuma, Damiana Scuteri, Giacinto Bagetta, Tsukasa Sakurada, Shinobu Sakurada   +7 more
doaj   +1 more source

Anti-allergic Drugs [PDF]

, 2019
ALLERGY is defined as a disease following a response by the IMMUNE SYSTEM to an otherwise innocuous antigen. Allergic diseases include allergic rhinitis, atopic dermatitis, systemic ANAPHYLAXIS, food ALLERGY, allergic ASTHMA and acute urticaria and are ...
McKay, Sue, Parnham, Michael J., Valesky, Eva M., Van Oosterhout, Antoon J.M.   +3 more
core   +1 more source

European Guideline on Chronic Nausea and Vomiting—A UEG and ESNM Consensus for Clinical Management

United European Gastroenterology Journal, Volume 13, Issue 3, Page 427-471, April 2025.
ABSTRACT Introduction Chronic nausea and vomiting are symptoms of a wide range of gastrointestinal and non‐gastrointestinal conditions. Diagnosis can be challenging and requires a systematic and well‐structured approach. If the initial investigation for structural, toxic and metabolic disorders is negative, digestive motility and gut‐brain interaction ...
Carolina Malagelada, Jutta Keller, Daniel Sifrim, Jordi Serra, Jan Tack, Agata Mulak, Andreas Stengel, Ariadna Aguilar, Asbjorn Mohr Drewes, Axel Josefsson, Bruno Bonaz, Dan Dumitrascu, Daniel Keszthelyi, Elizabeth Barba, Florencia Carbone, Frank Zerbib, Giovanni Marchegiani, Goran Hauser, Guillaume Gourcerol, Hans Tornblom, Heinz Hammer, Imran Aziz, Jelena Rakic Matic, Juan Mendive, Kornilia Nikaki, Lucas Wauters, Luis Gerardo Alcalá‐González, Marek Waluga, Mariana Jinga, Maura Corsetti, Nathalie Rommel, Ray Shidrawi, Roberto De Giorgio, Sritharan Kadirkamanathan, Teodora Surdea‐Blaga   +34 more
wiley   +1 more source

Histamine H1 receptor antagonists enhance the efficacy of antibacterials against Escherichia coli

BMC Veterinary Research, 2019
Background H1 receptor antagonists are commonly used for the treatment of allergic diseases. The aim of this study was to find out, if antihistaminic compounds like mepyramine have the ability to influence the activity of antibacterials.
G. G. Bruer, P. Hagedorn, M. Kietzmann, A. F. Tohamy, V. Filor, E. Schultz, S. Mielke-Kuschow, J. Meissner   +7 more
doaj   +1 more source

Effects of administration of histamine and its H1, H2, and H3 receptor antagonists into the primary somatosensory cortex on inflammatory pain in rats [PDF]

Iranian Journal of Basic Medical Sciences, 2014
Objective(s): The present study investigated the effects of microinjection of histamine and histamine H1, H2, and H3 receptor antagonists, chlorpheniramine, ranitidine and thioperamide, respectively into the primary somatosensory cortex (PSC) on ...
Esmaeal Tamaddonfard, Nasrin Hamzeh Gooshchi   +1 more
doaj  

Histamine modulation of urinary bladder urothelium, lamina propria and detrusor contractile activity via H1 and H2 receptors

Scientific Reports, 2019
The mechanisms underlying bladder contractile disorders such as overactive bladder are not fully understood, and there is limited understanding of the receptor systems modulating spontaneous bladder contractions.
Zane Stromberga, R. Chess-Williams, Christian Moro   +2 more
semanticscholar   +1 more source

Cytokine responses of intraepithelial lymphocytes are regulated by histamine H2 receptor [PDF]

, 2009
Backgrounds. Histamine participates in the immune regulation of several gastrointestinal diseases. However, the effect of histamine on intestinal intraepithelial lymphocytes (IELs), the front line of intestinal mucosal immune system, is not well ...
A Di Sabatino, A Hayday, A Mazzoni, Akira Hishida, B Lagier, C Lundqvist, CA Akdis, CA Akdis, CC Fox, D Montufar-Solis, E Bolton, E Masini, G Barbara, G Caron, G Monteleone, H Cheroutre, H Cheroutre, H Kiyono, HD Lim, HK Takahashi, IJ Elenkov, K Hoshino, K Takahashi, K Tomita, Kosuke Takagaki, L Knutson, L Lefrancois, LB Hough, LB Svendsen, LE Sander, M Jutel, M Kawaguchi, M Watanabe, Mutsuhiro Ikuma, N Osna, N Osna, P Parronchi, R Boismenu, R Leurs, RL Mosley, S Bischoff, S Kapoor, S Matsumoto, S Takamatsu, S Winterkamp, Satoshi Osawa, T Morichika, T Taguchi, T Taguchi, TA Barrett, Takahisa Furuta, Takanori Yamada, WJ Adams, WJ Adams, Y Horio, Y Sonobe, Yasuhiro Takayanagi, Yasushi Hamaya, Yoshiaki Horio   +58 more
core   +1 more source

The role of histamine in neurogenic inflammation [PDF]

, 2013
The term ‘neurogenic inflammation’ has been adopted to describe the local release of inflammatory mediators, such as substance P and calcitonin gene-related peptide, from neurons.
Fantozzi, Roberto, Rosa, ARIANNA CAROLINA   +1 more
core   +1 more source

Comparison and combination of ZEUS and H1 PDF analyses [PDF]

arXiv, 2005
The H1 and ZEUS published PDF analyses are compared, including a discussion of the different treatments of correlated systematic uncertainties. Differences in the data sets and the analyses are investigated by putting the H1 data set through both PDF analyses and by putting the ZEUS and H1 data sets through the same (ZEUS) analysis, separately. Finally
arxiv