Environmental enrichment as a multisystem modulator of neurotransmitter function: mechanisms, plasticity, and therapeutic implications. [PDF]
Singhal G, Baune BT.
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Pathophysiological Drivers of Mast Cell Activation Syndrome and Implications for Treatment. [PDF]
Collins S +3 more
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Cetirizine suppresses cancer-associated fibroblast-mediated fibrotic remodeling and epithelial-mesenchymal transition via histamine H<sub>1</sub> receptor inverse agonism. [PDF]
Sasaki A +12 more
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Dermographism in chronic spontaneous urticaria: associations with disease activity, autoimmunity, and disease duration. [PDF]
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Restless Legs Syndrome Associated With Fexofenadine Use: A Case Report. [PDF]
Albeshry AM.
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The effect of H1 and H2 histamine antagonists on symptomatic dermographism
British Journal of Dermatology, 1979In ten patients suffering from symptomatic dermographism the combined administration of chlorpheniramine + cimetidine produced a greater reduction in the weal and flare response provoked by a standardized scratch than the administration of chlorpheniramine alone. There was a statistically significant improvement in the overall assessment of the patient'
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Histamine is an important mediator for early phase allergic reactions that are involved in atopic diseases, mediated by specific IgE antibodies. After allergenic contact, its liberation induces unpleasant symptoms like itching, several manifestations as local vasodilatation, bronchoconstriction, mucus hypersecretion.
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