Results 41 to 50 of about 19,031 (233)

Role of Neuroinflammation in Autism Spectrum Disorder and the Emergence of Brain Histaminergic System. Lessons Also for BPSD?

Frontiers in Pharmacology, 2020
Many behavioral and psychological symptoms of dementia (BPSD) share similarities in executive functioning and communication deficits with those described in several neuropsychiatric disorders, including Alzheimer’s disease (AD), epilepsy, schizophrenia ...
Nermin Eissa, Nermin Eissa, Adel Sadeq, Astrid Sasse, Bassem Sadek, Bassem Sadek   +5 more
doaj   +1 more source

Random Antagonistic Matrices [PDF]

J. Phys. A: Math. Theor. 49 (2016) 375601 (16pp), 2016
The ensemble of antagonistic matrices is introduced and studied. In antagonistic matrices the entries $\mathcal A_{i,j}$ and $\mathcal A_{j,i}$ are real and have opposite signs, or are both zero, and the diagonal is zero. This generalization of antisymmetric matrices is suggested by the linearized dynamics of competitive species in ecology.
arxiv   +1 more source

Plasticity of histamine H3 receptor expression and binding in the vestibular nuclei after labyrinthectomy in rat [PDF]

, 2004
Background: In rat, deafferentation of one labyrinth (unilateral labyrinthectomy) results in a characteristic syndrome of ocular and motor postural disorders (e.g., barrel rotation, circling behavior, and spontaneous nystagmus). Behavioral recovery (e.g.,
Aarnisalo, Antti A., Karlstedt, Kaj, Lozada, Adrian F., Panula, Pertti, Stark, Holger   +4 more
core   +2 more sources

Sex-specific recombination rates and allele frequencies affect the invasion of sexually antagonistic variation on autosomes [PDF]

Journal of Evolutionary Biology 26 (2013) 2428, 2013
The introduction and persistence of novel sexually antagonistic alleles can depend upon factors that differ between males and females. Understanding the conditions for invasion in a two-locus model can elucidate these processes. For instance, selection can act differently upon the sexes, or sex-linkage can facilitate the invasion of genetic variation ...
arxiv   +1 more source

The association between histamine 2 receptor antagonist use and Clostridium difficile infection: a systematic review and meta-analysis. [PDF]

, 2013
Background Clostridium difficile infection (CDI) is a major health problem. Epidemiological evidence suggests that there is an association between acid suppression therapy and development of CDI.
A Deshpande, A Liberati, Abdur Rahman Khan, Adrian V. Hernandez, Alex J. Sutton, AR Manges, Aref A. Bin. Abdulhak, BR Dalton, C Bavishi, C Yip, CA Muto, CJ Cates, CS Kwok, CW Shi, DF Stroup, DO Lowe, DZ Bliss, E Brown, ER Dubberke, ER Dubberke, F Sundram, Faisal A. Alasmari, GH Guyatt, I Schuller, IM Tleyjeh, Imad M. Tleyjeh, J Erwin, J Leonard, J Pepin, J Zhang, JL Kuntz, JP Higgins, JP Higgins, KS Jung, L Kyne, Larry M. Baddour, LC McDonald, LK Archibald, LV McFarland, M Aseeri, M Beaulieu, M Egger, M Emoto, MD Howell, MD Redelings, Mohamad Al-Tannir, Muhammad Riaz, Musa A. Garbati, Mushabab AlGhamdi, N Peled, Patricia J. Erwin, PJ Netland, R DerSimonian, RL Jump, S Dial, S Dial, S Dial, S Dial, S Jayatilaka, S Khanna, S Modena, S Schneeweiss, S Shah, SB Debast, SK Nath, SV Kazakova, V Stevens, VG Loo, VG Loo, WR Jarvis   +69 more
core   +3 more sources

The Effects of Histaminergic Agents in the Nucleus Accumbens of Rats in the Elevated Plus-Maze Test of Anxiety

Basic and Clinical Neuroscience, 2010
Introduction/Aims: The nucleus accumbens (NAc) receives histaminergic neurons from tuberomammillary nuclei. There are also reports indicating that central histamine systems are involved in many physiological behavioral processes, including anxiety.
Mohammad-Reza Zarrindast, Saba Taherid, Ameneh Rezayof   +2 more
doaj   +2 more sources

Proton pump inhibitors and the risk of adverse cardiac events. [PDF]

PLoS ONE, 2013
Recent evidence suggests that proton pump inhibitors (PPIs) might be linked with adverse cardiac events, but a causal relationship is unproven.We applied the self-matched case series method to two studies using population-based health care data from ...
David N Juurlink, Colin R Dormuth, Anjie Huang, Chelsea Hellings, J Michael Paterson, Colette Raymond, Anita Kozyrskyj, Yola Moride, Erin M Macdonald, Muhammad M Mamdani   +9 more
doaj   +1 more source

Antioxidant and Anti-Glycation Potential of H2 Receptor Antagonists—In Vitro Studies and a Systematic Literature Review

Pharmaceuticals, 2023
Background: Histamine H2 receptor antagonists are a group of drugs that inhibit gastric juice secretion in gastrointestinal diseases. However, there is evidence to suggest that H2 blockers have a broader spectrum of activity.
Grzegorz Biedrzycki, Blanka Wolszczak-Biedrzycka, Justyna Dorf, Daniel Michalak, Małgorzata Żendzian-Piotrowska, Anna Zalewska, Mateusz Maciejczyk   +6 more
doaj   +1 more source

Extreme antagonism arising from gene-environment interactions [PDF]

, 2020
Antagonistic interactions in biological systems, which occur when one perturbation blunts the effect of another, are typically interpreted as evidence that the two perturbations impact the same cellular pathway or function. Yet, this interpretation ignores extreme antagonistic interactions wherein an otherwise deleterious perturbation compensates for ...
arxiv   +1 more source

Analytical and Pharmacological Characterization of 1‐(Furan‐2‐Carbonyl)‐LSD (1F‐LSD) and Comparison With 1‐(Thiophene‐2‐Carbonyl)‐LSD (1T‐LSD)

Drug Testing and Analysis, EarlyView.
The novel lysergamide 1‐(furan‐2‐carbonyl)‐LSD (1F‐LSD) was analytically characterized. 1F‐LSD showed LSD‐like activity in vivo similar to 1‐(thiophene‐2‐carbonyl)‐LSD (1T‐LSD) used for comparison. Administration studies in mice and LC–MS analysis revealed that 1F‐LSD served as a prodrug.
Simon D. Brandt, Pierce V. Kavanagh, Sarah Gare, Simon P. Elliott, Alexander Stratford, Adam L. Halberstadt   +5 more
wiley   +1 more source