Results 91 to 100 of about 1,480,236 (218)

Peculiarities of influence of single intragastric administration of H2-histamine receptor blockers of the second (nisatidine) and third (famotidine) generation on acid-peptic and mucoid-electrolyte secretion of the stomach in patients with duodenal ulcer

, 2019
Introduction. Antisecretory drugs are commonly used in the complex treatment of most diseases of the upper gastrointestinal tract. Today, proton pomp inhibitors (PPI) have a priority in the basic treatment for acid-dependent diseases of the ...
Pliatsko M.
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Pharmacology and Toxicology of Metiamide, a Histamine H2 - Receptor Antagonist [PDF]

, 2018
A brief review of the pharmacology and toxicology of metiamide, a histamine H2-receptor antagonist, is given, and evidence is presented to support the view that it inhibits gastric acid secretion by virtue of its H2-receptor antagonist activity.
Brimblecombe, R. W., Duncan, W.A.M., Parsons, M.E.   +2 more
core  

Histamine increases the expression of LOX-1 via H2 receptor in human monocytic THP-1 cells [PDF]

, 2001
Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is a member of the scavenger receptor family, and is known to be expressed in monocytes/macrophages.
Yoshitaka Murata, Sasaguri, Yasuyuki, Masako Nomaguchi, Tetsuo Hamada, Xu, Hui, Arima, Nobuyuki, Nobuyuki Arima, Hamada, Tetsuo, Satoshi Kimura, Murata, Yoshitaka, Kimura, Satoshi, Yasuyuki Sasaguri, Hui Xu, Akihide Tanimoto, Tanimoto, Akihide, Nomaguchi, Masako   +15 more
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Histamine H2 receptor activates adenylate cyclase and PLC via separate GTP-dependent pathways

, 1996
Previously, we demonstrated that a single histamine H2 receptor can couple to both the adenosine 3',5'-cyclic monophosphate and inositol 1,4,5-trisphosphate/intracellular Ca2+ signaling pathways in a stimulatory manner.
L. Wang, I. Gantz, J. DelValle
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Physiological implications of biased signaling at histamine H2 receptors.

Frontiers in Pharmacology, 2015
Histamine mediates numerous functions acting through its four receptor subtypes all belonging to the large family of seven transmembrane G-protein coupled receptors (GPCRs).
Natalia eAlonso, Natalia eAlonso, Carlos Daniel Zappia, Carlos Daniel Zappia, Maia eCabrera, Maia eCabrera, Carlos Alberto Davio, Carlos Alberto Davio, Carlos Alberto Davio, Carina eShayo, Carina eShayo, Federico eMonczor, Federico eMonczor, Natalia Cristina Fernandez, Natalia Cristina Fernandez   +14 more
doaj   +1 more source

Histamine H2-receptor of human and rabbit parietal cells

, 1987
The histamine H2-receptor on the human parietal cell has been characterized by using dose-response curves and the negative logarithm of the molar concentration of an antagonist (pA2) analyses of cimetidine antagonism of betazole, histamine, and ...
R. Leth, E. Fellenius, B. Elander, L. Olbe, U. Haglund   +4 more
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Characterization of H2 histamine receptor: linkage to both adenylate cyclase and [Ca2+]i signaling systems

, 1992
We undertook these studies to examine the intracellular mechanisms of histamine action using a rat hepatoma-derived cell line that had been transfected to express the H2 histamine receptor cDNA.
J. Delvalle, T. Yamada, L. Wang, I. Gantz   +3 more
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Histamine H2 receptor in blood cells: a suitable target for the treatment of acute myeloid leukemia [PDF]

, 2016
Acute myeloid leukemia (AML) consists in a cancer of early hematopoietic cells arising in the bone marrow, most often of those cells that would turn into white blood cells (except lymphocytes).
Davio, Carlos, Copsel, Sabrina, Shayo, Carina Claudia, Fernandez, Natalia, Monczor, Federico, Carina Shayo, Sabrina Copsel, Carlos Davio, Shayo, Carina, Federico Monczor, Fernandez, Natalia Cristina, Copsel, Sabrina Natalia, Natalia Fernandez, Davio, Carlos Alberto   +13 more
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Role of the Histaminergic System in the Inhibitory Effect of Melatonin on Broiler Chicken Feed Intake [PDF]

Poultry Science Journal
Prior investigations have postulated that melatonin, a prominent hormone produced by the pineal gland, can reduce animal food consumption. This study was designed to evaluate the involvement of central histamine H1 and H2 receptors in regulating ...
Majid Taati, Hassan Norouzian, Vahid Farhadi   +2 more
doaj   +1 more source

The mRNA expression and secretion of granzyme B are up-regulated via the histamine H2 receptor in human CD4⁺ T cells. [PDF]

Inflamm Res, 2023
Dawodu D, Sand S, Nikolouli E, Werfel T, Mommert S.   +4 more
europepmc   +1 more source