Results 101 to 110 of about 1,480,236 (218)

Molecular Encapsulation of Histamine H2-Receptor Antagonists by Cucurbit[7]Uril: An Experimental and Computational Study

Molecules, 2016
The histamine H2-receptor antagonists cimetidine, famotidine and nizatidine are individually encapsulated by macrocyclic cucurbit[7]uril (CB[7]), with binding affinities of 6.57 (±0.19) × 103 M−1, 1.30 (±0.27) × 104 M−1 and 1.05 (±0.33) × 105 M−1 ...
Hang Yin, Runmiao Wang, Jianbo Wan, Ying Zheng, Defang Ouyang, Ruibing Wang   +5 more
doaj   +1 more source

Allergic Rhinoconjunctivitis: the Role of Histamine

Mediators of Inflammation, 1994
Allergic rhinoconjunctivitis is the most common atopic condition encountered in clinical practice. Analysis of the pathogenesis of this condition permits identification of optimal therapeutic targets.
M. Andersson, L. Greiff, C. Svensson
doaj   +1 more source

Histamine H2 receptor antagonist exhibited comparable all-cause mortality-decreasing effect as β-blockers in critically ill patients with heart failure: a cohort study. [PDF]

Front Pharmacol, 2023
Zhang XS, Cai WK, Wang P, Xu R, Yin SJ, Huang YH, Guo Y, Jiang FF, Pan JM, Li YH, He GH.   +10 more
europepmc   +1 more source

Molecular basis for the interaction of histamine with the histamine H2 receptor.

Journal of Biological Chemistry, 1992
We undertook these studies to characterize the molecular basis of the interaction of histamine with the H2 receptor. Key areas of homology in the structures of the histamine H2 and beta 2 adrenergic receptor suggested specific transmembrane amino acids that might be important for binding of histamine.
I, Gantz, J, DelValle, L D, Wang, T, Tashiro, G, Munzert, Y J, Guo, Y, Konda, T, Yamada   +7 more
openaire   +2 more sources

Effect of histamine H1 and H2 receptor antagonists on histamine-induced macrophage LOX-1 mRNA expression.

, 2014
Monocyte-derived macrophages were incubated in the presence of 10 µM histamine and the indicated concentrations of the histamine H1 and H2 receptor antagonists (pyrilamine and ranitidine, respectively) for 4 h and analyzed for LOX-1 mRNA expression.
Petri T. Kovanen (188189), Mervi Alanne-Kinnunen (633861), Katariina Öörni (221897), Jani Lappalainen (245191)   +3 more
core   +1 more source

Histamine H₂ receptor deficit in glutamatergic neurons contributes to the pathogenesis of schizophrenia. [PDF]

Proc Natl Acad Sci U S A, 2023
Ma Q, Jiang L, Chen H, An D, Ping Y, Wang Y, Dai H, Zhang X, Wang Y, Chen Z, Hu W.   +10 more
europepmc   +1 more source

Effects of administration of histamine and its H1, H2, and H3 receptor antagonists into the primary somatosensory cortex on inflammatory pain in rats [PDF]

Iranian Journal of Basic Medical Sciences, 2014
Objective(s): The present study investigated the effects of microinjection of histamine and histamine H1, H2, and H3 receptor antagonists, chlorpheniramine, ranitidine and thioperamide, respectively into the primary somatosensory cortex (PSC) on ...
Esmaeal Tamaddonfard, Nasrin Hamzeh Gooshchi   +1 more
doaj  

Molecular basis for the repurposing of histamine H2-receptor antagonist to treat COVID-19. [PDF]

J Biomol Struct Dyn, 2022
Ishola AA, Joshi T, Abdulai SI, Tijjani H, Pundir H, Chandra S.   +5 more
europepmc   +1 more source

Development of novel ligands influencing neurotransmission in the central nervous system [PDF]

, 2007
The development of novel drugs targeting GPCRs is of particular interest since modulation of subfamilies of this receptor class highly influences neurotransmission in the central nervous system.
Sasse, Britta Caroline
core  

Association of proton pump inhibitor and histamine H2-receptor antagonists with restless legs syndrome. [PDF]

Sleep, 2021
Earley EJ, Didriksen M, Spencer BR, Kiss JE, Erikstrup C, Pedersen OB, Sørensen E, Burgdorf KS, Kleinman SH, Mast AE, Busch MP, Ullum H, Page GP.   +12 more
europepmc   +1 more source