Results 51 to 60 of about 1,480,236 (218)
The Journal of Dermatology, EarlyView.ABSTRACT Physical urticaria is a subtype of chronic inducible urticaria characterized by wheals and/or angioedema triggered by physical stimuli. We report a refractory case of combined localized heat urticaria, delayed solar urticaria, and symptomatic dermographism in a 16‐year‐old girl.
Shuta Yoshitani +2 more
wiley +1 more source
Brazilian Journal of Medical and Biological Research, 1997 The possible role of histamine receptors in the hippocampal formation on the exploratory motivation and emotionality of the rat was studied. An elevated asymmetric plus-maze composed of 4 different arms (no walls, single high wall, high and low walls and
M.B. Ruarte, A.G. Orofino, E.O. Alvarez
doaj +1 more source
Identification and characterization of ZEL-H16 as a novel agonist of the histamine H3 receptor. [PDF]
PLoS ONE, 2012 The histamine H3 receptor (H3R) has been recognized as a promising target for the treatment of various central and peripheral nervous system diseases.
Ying Shi +9 more
doaj +1 more source
Allergy, EarlyView.ABSTRACT These updated EAACI guidelines aim to standardize skin testing methodologies for both immediate and non‐immediate drug hypersensitivity reactions. For immediate reactions, the optimal testing window is 4–6 weeks post‐reaction; whereas beyond 6 months, false‐negative results increase.
Annick Barbaud +14 more
wiley +1 more source
Ambivalence of drug metabolism: Exploration of cilazapril and candesartan prodrugs for transdermal delivery and search for toxic reactive intermediates of N(G)-acylated hetarylpropylguanidines [PDF]
, 2012 Figuratively, drug metabolism can be considered as two sides of the same coin; one leading to desired, beneficial effects, e.g. by activation of prodrugs, whereas the other one results in adverse side effects due to toxic metabolites.
Ertel, Miriam
core +1 more source
Inflammatory and Immunological Basis of Periodontal Diseases
Journal of Periodontal Research, EarlyView.The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima +3 more
wiley +1 more source
Involvement of histamine H1 and H2 receptor inverse agonists in receptor's crossregulation [PDF]
, 2019 Histamine [2-(4-Imidazolyl)-ethylamine] modulates different biological processes, through histamine H1 and H2 receptors, and their respective blockers are widely used in treating allergic and gastric acid-related disorders.
Zappia, Carlos Daniel +9 more
core +1 more source
Veterinary Dermatology, EarlyView.Background: Currently used methods for the interpretation of intradermal allergen test results either ignore the erythema of the wheals (objective method) or evaluate it subjectively (subjective method, and global wheal score [GWS]). Objectives: To compare the efficacy of GWSs in differentiating between wheals induced by intradermal injection of a ...
Ana Petak +5 more
wiley +1 more source
Histamine elicits glutamate release from cultured astrocytes
Journal of Pharmacological Sciences, 2018 Astrocytes play key roles in regulating brain homeostasis and neuronal activity. This is, in part, accomplished by the ability of neurotransmitters in the synaptic cleft to bind astrocyte membrane receptors, activating signalling cascades that regulate ...
Anikó Kárpáti +7 more
doaj +1 more source
DEN Open, Volume 7, Issue 1, April 2027.ABSTRACT Background and Aim: Obscure gastrointestinal bleeding (OGIB) is defined as bleeding of unknown origin after comprehensive upper, lower, and small‐bowel evaluations. However, the incidence and predictors of rebleeding after negative comprehensive gastrointestinal evaluation remain unclear.
Sachiyo Onishi +8 more
wiley +1 more source