The Roles of Cardiovascular H2-Histamine Receptors Under Normal and Pathophysiological Conditions [PDF]
Frontiers in Pharmacology, 2021 This review addresses pharmacological, structural and functional relationships among H2-histamine receptors and H1-histamine receptors in the mammalian heart.
Joachim Neumann +4 more
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Histamine Receptors: Ex Vivo Functional Studies Enabling the Discovery of Hits and Pathways [PDF]
Membranes, 2023 Histamine receptors (HRs) are G-protein-coupled receptors involved in diverse responses triggered by histamine release during inflammation or by encounters with venomous creatures.
Andrea Seldeslachts +2 more
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Histamine and histamine receptors: Roles in major depressive disorder [PDF]
Frontiers in Psychiatry, 2022 Although the incidence of major depressive disorder (MDD) is high and its social impact is great, we still know very little about the pathophysiology of depression.
Hong Qian +4 more
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Molecular Modeling of Histamine Receptors—Recent Advances in Drug Discovery [PDF]
Molecules, 2021 The recent developments of fast reliable docking, virtual screening and other algorithms gave rise to discovery of many novel ligands of histamine receptors that could be used for treatment of allergic inflammatory disorders, central nervous system ...
Pakhuri Mehta +2 more
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Histamine, histamine receptors, and neuropathic pain relief. [PDF]
Br J Pharmacol, 2020 Histamine, acting via distinct histamine H1, H2, H3, and H4 receptors, regulates various physiological and pathological processes, including pain. In the last two decades, there has been a particular increase in evidence to support the involvement of H3 receptor and H4 receptor in the modulation of neuropathic pain, which remains challenging in terms ...
Obara I +3 more
europepmc +6 more sources
Correlation of Histamine Receptors and Adrenergic Receptor in Broilers Appetite [PDF]
Archives of Razi Institute, 2022 The current study was conducted to investigate the interaction between the central adrenergic and histaminergic systems and the broiler chick’s feed intake.
M Daneshvar +3 more
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Differential expression of histamine receptors in the bladder wall tissues of patients with bladder pain syndrome/interstitial cystitis – significance in the responsiveness to antihistamine treatment and disease symptoms [PDF]
BMC Urology, 2019 Background Activation of mast cells plays an important role in the pathogenesis of bladder pain syndrome/interstitial cystitis (BPS/IC). Histamine, a mast cell-derived mediators, induced inflammation and hypersensitivity of the bladder. The present study
Hui Shan +6 more
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Histamine upregulates the expression of histamine receptors and increases the neuroprotective effect of astrocytes [PDF]
Journal of Neuroinflammation, 2018 Background Astrocytes have attracted increasing attention over recent decades for their role in neuroinflammation. Histamine, a major aminergic brain neurotransmitter, has an important influence on the main activities of astrocytes, such as ion ...
Jiawen Xu +7 more
doaj +2 more sources
Histamine is involved in the regulation of collagen content in cultured heart myofibroblasts via H2, H3 and H4 histamine receptors. [PDF]
Biomed Rep, 2021 Piera L +3 more
europepmc +3 more sources