Results 21 to 30 of about 98,227 (378)
Histamine receptors and cancer pharmacology [PDF]
British Journal of Pharmacology, 2010 Considerable evidence has been collected indicating that histamine can modulate proliferation of different normal and malignant cells. High histamine biosynthesis and content together with histamine receptors have been reported in different human neoplasias including melanoma, colon and breast cancer, as well as in experimental tumours in which ...
Elena Rivera +2 more
openaire +4 more sources
Bottom-Up versus Top-Down Induction of Sleep by Zolpidem Acting on Histaminergic and Neocortex Neurons [PDF]
, 2016 Zolpidem, a GABAA receptor-positive modulator, is the gold-standard drug for treating insomnia. Zolpidem prolongs IPSCs to decrease sleep latency and increase sleep time, effects that depend on α2 and/or α3 subunit-containing receptors.
Brickley, SG +9 more
core +4 more sources
Functional Diversity of Histamine and Histamine Receptors
Journal of Investigative Dermatology, 1992 In order to analyze the mechanisms by which a single biogenic amine like histamine is capable of inducing a wide variety of both physiologic and pathologic functions in various tissues/cells, histamine responses were dissected in detail from a biochemical and pharmacologic point of view.
Donald G. Payan, Masato Mitsuhashi
openaire +3 more sources
Histamine H1 and H2 Receptor Antagonists Accelerate Skin Barrier Repair and Prevent Epidermal Hyperplasia Induced by Barrier Disruption in a Dry Environment [PDF]
, 2001 Keratinocytes have histamine H1 and H2 receptors, but their functions are poorly understood. To clarify the role of histamine receptors in the epidermis, we examined the effects of histamine receptor antagonists and agonists applied epicutaneously on the
Ashida, Yutaka +2 more
core +1 more source
Regulation of the immune response and inflammation by histamine and histamine receptors [PDF]
Journal of Allergy and Clinical Immunology, 2011 Histamine is a biogenic amine with extensive effects on many cell types, including important immunologic cells, such as antigen-presenting cells, natural killer cells, epithelial cells, and T and B lymphocytes. Histamine and its 4 receptors represent a complex system of immunoregulation with distinct effects dependent on receptor subtypes and their ...
O'Mahony Liam +2 more
openaire +4 more sources
Effects of histamine on human periodontal ligament fibroblasts under simulated orthodontic pressure.
PLoS ONE, 2020 As type-I-allergies show an increasing prevalence in the general populace, orthodontic patients may also be affected by histamine release during treatment.
Marcella Groeger +6 more
doaj +1 more source
Nature Communications, 2023 Histamine is a biogenic amine that participates in allergic and inflammatory processes by stimulating histamine receptors. The histamine H4 receptor (H4R) is a potential therapeutic target for chronic inflammatory diseases such as asthma and atopic ...
Dohyun Im +10 more
doaj +1 more source
Revising Berg-Purcell for finite receptor kinetics [PDF]
, 2021 From nutrient uptake, to chemoreception, to synaptic transmission, many systems in cell biology depend on molecules diffusing and binding to membrane receptors. Mathematical analysis of such systems often neglects the fact that receptors process molecules at finite kinetic rates.
arxiv +1 more source
New Developments in the Use of Histamine and Histamine Receptors [PDF]
Current Allergy and Asthma Reports, 2010 Histamine and the histamine receptors are important regulators of a plethora of biological processes, including immediate hypersensitivity reactions and acid secretion in the stomach. In these roles, antihistamines have found widespread therapeutic applications, while the last receptor to be discovered, the H4 histamine receptor, has become a major ...
Craig Smuda, Paul J. Bryce
openaire +3 more sources
Plasticity of histamine H3 receptor expression and binding in the vestibular nuclei after labyrinthectomy in rat [PDF]
, 2004 Background: In rat, deafferentation of one labyrinth (unilateral labyrinthectomy) results in a characteristic syndrome of ocular and motor postural disorders (e.g., barrel rotation, circling behavior, and spontaneous nystagmus). Behavioral recovery (e.g.,
Aarnisalo, Antti A. +4 more
core +2 more sources