Results 101 to 110 of about 26,592 (294)

Progress in Allergy Signal Research on Mast Cells: Up-Regulation of Histamine Signal-Related Gene Expression in Allergy Model Rats

Journal of Pharmacological Sciences, 2008
Brown Norway allergy model rats sensitized to toluene 2,4-diisocyanate (TDI) were developed. Histamine H1receptor mRNA level was elevated in nasal mucosa of allergy model rats after the provocation with TDI, which was followed by H1-receptor up ...
Hiroyuki Fukui
doaj  

Sleep-waking discharge of ventral tuberomammillary neurons in wild-type and histidine decarboxylase knock-out mice

Frontiers in Behavioral Neuroscience, 2010
Using extracellular single unit recordings, we have determined the characteristics of neurons in the ventral tuberomammillary nucleus (VTM) of wild-type (WT) and histidine decarboxylase knock-out (HDC-KO) mice during the sleep-waking cycle.
Kazuya Sakai, Kazushi Takahashi, Christelle Anaclet, Jian-Sheng Lin   +3 more
doaj   +1 more source

Antihistamines suppress upregulation of histidine decarboxylase gene expression with potencies different from their binding affinities for histamine H1 receptor in toluene 2,4-diisocyanate-sensitized rats

Journal of Pharmacological Sciences, 2016
Antihistamines inhibit histamine signaling by blocking histamine H1 receptor (H1R) or suppressing H1R signaling as inverse agonists. The H1R gene is upregulated in patients with pollinosis, and its expression level is correlated with the severity of ...
Hiroyuki Mizuguchi, Asish K. Das, Kazutaka Maeyama, Shrabanti Dev, Masum Shahriar, Yoshiaki Kitamura, Noriaki Takeda, Hiroyuki Fukui   +7 more
doaj   +1 more source

Role of histidine decarboxylase gene in the pathogenesis of Tourette syndrome. [PDF]

Brain Behav, 2022
Xu L, Zhang C, Zhong M, Che F, Guan C, Zheng X, Liu S.   +6 more
europepmc   +1 more source

Exploring dimethylsulfate for in vivo proteome footprinting [PDF]

arXiv, 2010
Protein footprinting is a new methodology that is based on probing, typically with the use of mass spectrometry, of reactivity of different aminoacid residues to a modifying reagent. Data thus obtained allow one to make inferences about protein conformations and their intermolecular interactions.
arxiv  

T cell cross-reactivity between coxsackievirus and glutamate decarboxylase is associated with a murine diabetes susceptibility allele. [PDF]

, 1994
Limited regions of amino acid sequence similarity frequently occur between microbial antigens and host proteins. It has been widely anticipated that during infection such sequence similarities could induce cross-reactive T cell responses, thereby ...
Kaufman, DL, Lehmann, PV, Tian, J
core  

Gut microbiota role in dietary protein metabolism and health-related outcomes: The two sides of the coin [PDF]

, 2016
Background: Human gut bacteria can synthesize proteinogenic amino acids and produce a range of metabolites via protein fermentation, some known to exert beneficial or harmful physiological effects on the host.
Beaumont, Martin, Blachier, François, Davila, Anne-Marie, Portune, Kevin J., Sanz Herranz, Yolanda, Tomé, Daniel   +5 more
core   +2 more sources

Acute ethanol treatment upregulates th1, th2 and hdc in larval zebrafish in stable networks

Frontiers in Neural Circuits, 2013
Earlier studies in zebrafish have revealed that acutely given ethanol has a stimulatory effect on locomotion in fish larvae but the mechanism of this effect has not been revealed.
Henri ePuttonen, Maria eSundvik, Stanislav eRozov, Yu-Chia eChen, Pertti ePanula   +4 more
doaj   +1 more source

Prevalence of Histidine Decarboxylase Genes of Gram-Positive Bacteria in Surströmming as Revealed by qPCR. [PDF]

Indian J Microbiol, 2021
Belleggia L, Milanović V, Cardinali F, Garofalo C, Clementi F, Aquilanti L, Osimani A.   +6 more
europepmc   +1 more source

Amino Acid Distributions and the Effect of Optimal Growth Temperature [PDF]

arXiv, 2013
We perform an exhaustive analysis of genome statistics for organisms, particularly extremophiles, growing in a wide range of physicochemical conditions. Specifically, we demonstrate how the correlation between the frequency of amino acids and their molecular weight, preserved on average, typically decreases as optimal growth temperature increases.
arxiv