Results 171 to 180 of about 966,943 (338)

Comparative analysis of the molecular starvation response of Southern Ocean copepods

open access: yesMolecular Ecology, EarlyView.
Abstract Large lipid‐storing copepods dominate mesozooplankton biomass in the polar oceans and form a critical link between primary production and higher trophic levels. The ecological success of these species depends on their ability to survive periods of food deprivation in a highly seasonal environment, but the molecular changes that mediate ...
Cory A. Berger   +3 more
wiley   +1 more source

Interdomain Linkers Regulate Histidine Kinase Activity by Controlling Subunit Interactions. [PDF]

open access: yesBiochemistry, 2022
Maschmann Z   +3 more
europepmc   +1 more source

Genome‐Wide Analysis of DtxR and HrrA Regulons Reveals Novel Targets and a High Level of Interconnectivity Between Iron and Heme Regulatory Networks in Corynebacterium glutamicum

open access: yesMolecular Microbiology, EarlyView.
Iron is essential for life, yet excessive levels can quickly lead to cellular damage via oxidative stress, underscoring the need for global regulators of iron and heme homeostasis. In this study, we present a genome‐wide analysis of the binding patterns of DtxR and HrrA in Corynebacterium glutamicum.
Aileen Krüger   +2 more
wiley   +1 more source

Sensor histidine kinase is a β-lactam receptor and induces resistance to β-lactam antibiotics

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2016
Lu Li   +5 more
semanticscholar   +1 more source

Staphylococcus aureus COL: An Atypical Model Strain of MRSA That Exhibits Slow Growth and Antibiotic Tolerance due to a Mutation in PRPP Synthetase

open access: yesMolecular Microbiology, EarlyView.
COL is an unusual “model” strain of Staphylococcus aureus that exhibits slow growth and multidrug antibiotic tolerance. This phenotype is primarily due to a mutation in Prs, which synthesizes the core metabolite phosphoribosyl pyrophosphate (PRPP). Introduction of the COL Prs allele into the antibiotic‐susceptible strain Newman confers tolerance, while
Claire E. Stevens   +5 more
wiley   +1 more source

Atypical modes of bacterial histidine kinase signaling

open access: yesMolecular Microbiology, 2017
Jonathan W Willett, S. Crosson
semanticscholar   +1 more source

An HWE‐Family Histidine Kinase Modulates Brucella Cell Envelope Properties and Host Innate Immune Response

open access: yesMolecular Microbiology, EarlyView.
The HWE‐family histidine kinase PhyK regulates the cell envelope structure of the intracellular pathogen Brucella ovis and affects how the host immune system responds to this bacterium. Deletion of phyK alters bacterial survival in the face of detergent stress and reduces immune activation in infected macrophages.
Xingru Chen   +6 more
wiley   +1 more source

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