Results 231 to 240 of about 82,686 (281)

Mycobacterial MutT1-mediated dephosphorylation of the sensor histidine kinases reveals a new link in the regulation of the two-component signaling [PDF]

Elhassan Ali Fathi Emam, Devendra Pratap Singh, Deepak Kumar Saini, Umesh Varshney   +3 more
openalex   +1 more source

Manipulation of Wnt/β‐Catenin Signaling by Synthetic Frizzled Agonist and LRP Antagonist in Organoid Cultures and In Vivo

Small Methods, Volume 10, Issue 2, 22 January 2026.
Harnessing synthetic key receptor modulators, this study presents a breakthrough in Wnt/β‐catenin regulation. The FZD agonist RRP‐pbFn bypasses LRP5/6 to drive organoid expansion and tissue regeneration, while the LRP antagonist RRP‐Dkk1c eradicates tumors. These tools enable precise pathway control, advancing regenerative and cancer therapies.
Quanhui Dai, Jiawen Wang, Zihuan Lin, Danni Yu, Hui Yang, Jinsong Wei, Xiaoyu Li, Hao Hu, Chao Ni, Bing Zhao   +9 more
wiley   +1 more source

Comparison of Predatory Phenotypes and Genotypes Between Bdellovibrio sp. BIS2 and Bacteriovorax sp. HI3 Isolated From the Same Freshwater Environment

Environmental Microbiology, Volume 28, Issue 1, January 2026.
Bdellovibrio and like organisms (BALOs) have gained attraction owing to their ecological and practical significance. This study comparatively investigated two BALO strains from the same freshwater pond, Bdellovibrio sp. BIS2 and Bacteriovorax sp. HI3, and revealed significant variation in their predatory behaviours and associated genetic profiles ...
Tomomi Sugiyama, Tsubasa Kojima, Naoki A. Uemura, Daisuke Nakane, Hideo Dohra, Daisuke Inoue, Michihiko Ike   +6 more
wiley   +1 more source

The N-terminus of the Aspergillus fumigatus group III hybrid histidine kinase TcsC is essential for its physiological activity and targets the protein to the nucleus. [PDF]

mBio
Vincek A, Wolf A, Thomas A, Ebel F, Schruefer S.   +4 more
europepmc   +1 more source

Genetics of conditional extended mycelial cell viability of Streptomyces minutiscleroticus in deep starvation phase implicates the involvement of (p)ppGpp, clpX, and a histidine kinase sasA. [PDF]

Front Microbiol
Chatupale V, Pohnerkar J.
europepmc   +1 more source

STAT3 SH2 Domain Aspartic Acid 661 Mutations Activate Immune Gene Programs

Journal of Cellular and Molecular Medicine, Volume 30, Issue 1, January 2026.
ABSTRACT The conserved aspartic acid residue D661 within the STAT3 SH2 domain is a recurrent mutational hotspot in hematologic malignancies, including T‐cell large granular lymphocytic leukaemia, myelodysplastic syndromes and acute lymphoblastic leukaemia. To define the functional consequences of distinct STAT3D661 variants, we integrated computational,
Hye Kyung Lee, Gyuhyeok Cho, Jichun Chen, Aaron B. Schultz, Sung‐Gwon Lee, Chengyu Liu, Priscilla A. Furth, Neal S. Young, Jungwook Kim, Alejandro Villarino, Lothar Hennighausen   +10 more
wiley   +1 more source

Genetic Diversity of Polymyxin Resistance Genes in Klebsiella pneumoniae Clinical Isolates

Molecular Ecology, Volume 35, Issue 2, January 2026.
ABSTRACT This study investigates the genetic diversity and evolutionary mechanisms driving polymyxin resistance in Klebsiella pneumoniae, a critical priority pathogen. By analysing mgrB, phoPQ and pmrAB genes in susceptible (PM‐S) and resistant (PM‐R) populations through neutrality tests (Tajima D, Fu & Li's D) we uncovered polygenic adaptation and ...
Daniel Miceli Serwy, Maria Eduarda Rocha Conde, Ana Luiza Carneiro Alencar, Roberto Leonan Morim Novaes, Josué da Costa Lima‐Junior, Fabio Faria da Mota, Ana Paula Carvalho‐Assef, Teca Calcagno Galvao, Viviane Zahner   +8 more
wiley   +1 more source

The Ralstonia solanacearum E3 Ligase Effector RipV1 Targets Plant U‐Box Domain‐Containing Receptor‐Like Cytoplasmic Kinases That Negatively Regulate Immunity in Nicotiana benthamiana

Molecular Plant Pathology, Volume 27, Issue 1, January 2026.
The Ralstonia solanacearum Novel E3 Ligase effector RipV1 ubiquitinates and enhances the accumulation of the plant U‐box‐containing receptor‐like cytoplasmic protein RLCK‐IXb‐1 that negatively regulates immune signalling. ABSTRACT Plants detect microbe‐associated molecular patterns from pathogens via plasma membrane‐localised receptors, which activate ...
Jihyun Choi, Thakshila Dharmasena, Yoonyoung Lee, Jacqueline Monaghan, Cécile Segonzac   +4 more
wiley   +1 more source

Cross-Phosphorylation between AgrC Histidine Kinase and the Noncognate Response Regulator Lmo1172 in Listeria monocytogenes under Benzalkonium Chloride Stress. [PDF]

Microorganisms
Yu T, Jiang X, Xu X, Xu P, Qiu S, Yin J, Hamilton DP, Jiang X.   +7 more
europepmc   +1 more source