Results 1 to 10 of about 38,208 (195)

Langerhans‐Cell Histiocytosis [PDF]

open access: yesIndian Journal of Medical Research, 2018
Langerhans cell histiocytosis (LCH) formerly known as pulmonary eosinophilic granuloma is currently regarded by the World Health Organization as a clonal neoplastic proliferation of histiocytes.
C. Allen, M. Merad, K. McClain
semanticscholar   +6 more sources

Langerhans Cell histiocytosis. [PDF]

open access: yesBlood, 2020
Langerhans Cell Histiocytosis (LCH) is caused by clonal expansion of myeloid precursors that differentiate into CD1a+/CD207+ cells in lesions that leads to a spectrum of organ involvement and dysfunction.
C. Rodríguez-Galindo, C. Allen
semanticscholar   +4 more sources

Adult-onset perianal Langerhans cell histiocytosis presenting as pruritus ani: a case report and review of the literature

open access: yesJournal of Medical Case Reports, 2021
Background Langerhans cells belong to the histiocytic system and give rise to two tumors: Langerhans cell histiocytosis and Langerhans cell sarcoma. Clinical aggressiveness and degree of atypia distinguish the two neoplasms. Langerhans cell histiocytosis
Marah Hamdan, Jesse C. Qiao, Vid Fikfak
doaj   +2 more sources

Langerhans Cell Histiocytosis With <i>MAP2K1<sup>E102_I103del</sup></i> Mutation Successfully Treated With Trametinib. [PDF]

open access: yesEJHaem
ABSTRACT The discovery of the MAPK pathway mutations in lesions of patients with Langerhans cell histiocytosis (LCH) has made targeted therapy an important therapeutic approach for these patients. Theoretically, the RAF‐independent mutation MAP2K1E102_I103del is naturally resistant to allosteric MEK inhibitors.
Lang M, Chang L, Cao XX.
europepmc   +2 more sources

Erdheim-Chester Disease Manifesting Without Long Bone Involvement. [PDF]

open access: yesRespirol Case Rep
We present an atypical case of Erdheim–Chester Disease (ECD) due to the absence of skeletal involvement despite widespread infiltration of other organs. ABSTRACT Erdheim–Chester Disease (ECD) is an extremely rare, non‐Langerhans cell histiocytosis characterised by the proliferation of foamy histiocytes infiltrating various organs.
Sivasubramanian D   +6 more
europepmc   +2 more sources

Polyostotic Langerhans cell histiocytosis presenting as halitosis in a 24-year-old man: a case report [PDF]

open access: yesJournal of Medical Case Reports
Background Langerhans cell histiocytosis is a rare disease of the reticuloendothelial system. This report presents a novel case of Langerhans cell histiocytosis with systemic involvement that started with a simple chief complaint.
Hassan Mirmohammad Sadeghi   +6 more
doaj   +2 more sources

Langerhans cell histiocytosis [PDF]

open access: yesSão Paulo Medical Journal, 1998
The authors present a rare case of Langerhans cell histiocytosis in a 31 year old female patient with vulvar, peri-anal and oral lesions, diabetes insipidus, pulmonary skin and bone infiltrations.
Maria de Lourdes L. F. Chauffaille   +10 more
doaj   +7 more sources

Insights into etiology and management of a case of Langerhans cell histiocytosis manifesting as perianal lesions: a case report [PDF]

open access: yesJournal of Medical Case Reports
Background Langerhans cell histiocytosis is a rare disorder characterized by abnormal proliferation of Langerhans cells, primarily affecting children and occasionally adults.
Pei Xiao-yue, Tai Zixin, Zhang Wen-jun
doaj   +2 more sources

A case of diagnosis and treatment of mediastinal Langerhans cytosis [PDF]

open access: yesJournal of Cardiothoracic Surgery
Background Langerhans cell histiocytosis (LCH) is a rare disease. It mainly involves abnormal proliferation and aggregation of Langerhans cells, a type of cell of the immune system.Langerhans cytosis is more common in the bone, but it has rarely been ...
Yumeng Niu   +5 more
doaj   +2 more sources

Langerhans cell histiocytosis

open access: yesКлинический разбор в общей медицине, 2023
Langerhans cell histiocytosis is a rare proliferative disease of histiocyte-like cells, the peak incidence of which occurs in early childhood. Pulmonary Langerhans Cell Histiocytosis is one of the forms of this disease, but it usually affects young ...
Victor V. Fomin   +4 more
doaj   +2 more sources

Home - About - Disclaimer - Privacy