Results 11 to 20 of about 14,204,460 (231)

Targeted proteomics reveal histiocytosis-associated neurodegeneration signatures. [PDF]

Hemasphere
Abstract Neurodegeneration (ND) is a severe complication of Langerhans cell histiocytosis (LCH), yet its underlying biology and reliable biomarkers remain poorly defined. The aim of this study was to (1) gain insight into neuroimmunological mechanisms governing ND and (2) assess the clinical value of established and novel biomarkers for ND‐LCH.
Kvedaraite E, Lourda M, Munting JB, Papo M, Jädersten M, Shioda Y, Sakamoto K, Muñoz DM, Andriopoulos P, Pegoraro F, Laurencikas E, Kühnle I, Wille J, Naeije L, Olkinuora H, Sinha I, Hagey DW, Olsson-Åkefeldt S, Cohen-Aubart F, Österlundh G, Svensson M, Idbaih A, Piehl F, Blennow K, Zetterberg H, von Bahr TG, Gavhed D, Morimoto A, Haroche J, Henter JI.   +29 more
europepmc   +2 more sources

Histiocytosis development and clinical variation through the lens of genomics. [PDF]

J Pathol
Abstract Histiocytic neoplasms are rare haematologic diseases characterised by clonal expansions of cells with a monocyte, macrophage or dendritic cell phenotype. Their clinical manifestations are diverse, ranging from indolent lesions to aggressive systemic disease.
Kemps PG, van Halteren AG, van Wezel T, Hogendoorn PC.   +3 more
europepmc   +2 more sources

Langerhans Cell Histiocytosis in Adults: A Canadian Multicenter Case Series. [PDF]

Hematol Oncol
ABSTRACT Langerhans cell histiocytosis (LCH) is a rare clonal myeloid neoplasm. Canadian data on clinical characteristics, molecular profile, and treatment outcomes is limited. This study aims to report the initial experience of a Canadian rare diseases program, reflecting “real‐world” diagnostic pathways, referral patterns, and treatment heterogeneity
Quon S, Gummadi Y, Elsharawi I, Dobson J, Goubran M, Stubbins RJ, Diamond EL, Chen LYC.   +7 more
europepmc   +2 more sources

Late-Onset Langerhans Cell Histiocytosis Presenting with Seizures and Bilateral Temporal Involvement

, 2022
Langerhans cell histiocytosis is known as a rare childhood disease. In this case, we wanted to share our patient’s experience whose first symptom was an epileptic seizure, which attracted attention at an advanced age and revealed bilateral temporal lobe ...
Özge Öcek, Hasan Kuş, Pınar Ortan
core   +1 more source

Clinical periodontal diagnosis

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases include pathological conditions elicited by the presence of bacterial biofilms leading to a host response. In the diagnostic process, clinical signs such as bleeding on probing, development of periodontal pockets and gingival recessions, furcation involvement and presence of radiographic bone loss should be assessed prior ...
Giovanni E. Salvi, Andrea Roccuzzo, Jean‐Claude Imber, Alexandra Stähli, Björn Klinge, Niklaus P. Lang   +5 more
wiley   +1 more source

Longitudinal Monocyte Subset Dynamics as Biomarker in Adult Histiocytosis: Association With Mutational Status, Kinase Inhibitor Exposure and Relapse Risk. [PDF]

Hematol Oncol
Hematological Oncology, Volume 44, Issue 5, September 2026.
Razanamahery J, Raymond C, Papo M, Pegoraro F, Guy J, Aho LS, Emile JF, Samson M, Audia S, Haroche J, Bonnotte B.   +10 more
europepmc   +2 more sources

Non-Langerhans cell histiocytosis in a child with Kawasaki disease

BMJ Case Reports, 2009
Polymorphous skin rashes are one of the major presentations in children with Kawasaki disease. This report describes an unusual presentation of a skin rash (non-Langerhans cell histiocytosis) in a 4-month-old baby with resistance to intravenous immunoglobulin (IVIG) treatment and coronary artery dilatation.
Ho-Chang, Kuo, Chih-Chiang, Wu, Tsung-Hsien, Yang, Hong-Ren, Yu, Chi-Di, Liang, Yi-Ju, Chen, Kuender D, Yang   +6 more
openaire   +3 more sources

Non‐Langerhans cell histiocytosis xanthogranuloma patient with varying histopathology leading to progressive nodular histiocytosis

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, 2021
restriction
Yeongjoo, Oh, Jemin, Kim, Chang Ook, Park   +2 more
openaire   +3 more sources

PAPULAR HISTIOCYTOSIS OF HEAD : TYPE OF NON - LANGERHANS CELLS HISTIOCYTOSIS

Journal of Evolution of Medical and Dental Sciences, 2014
Papular histiocytosis of the head also known as benign cephalic histiocytosis is a rare, self-limiting histiocytosis that typically starts in early childhood. 1 Erythematous macules, papules and nodules develop on cheeks and spread to the forehead, earlobes and neck. Lesions are asymptomatic, gradually become reddish brown and may spread to involve the
Anil Kumar Gupta, Gaurav Murti
openaire   +1 more source

Orbital mass and hairy kidney as characteristics of Erdheim‐Chester disease

Clinical Case Reports, 2021
Erdheim‐Chester disease (ECD) is a rare non‐Langerhans cell histiocytosis, involving multiple organs. We report a case of ECD with typical features of an orbital mass and "hairy kidneys," whose recognition can lead to early diagnosis and treatment.
Koichiro Yamamoto, Kosuke Oka, Kou Hasegawa, Fumio Otsuka   +3 more
doaj   +1 more source