Results 91 to 100 of about 6,935 (192)

Norovirus Gastroenteritis Outbreak with a Secretor-independent Susceptibility Pattern, Sweden

Emerging Infectious Diseases, 2010
Norovirus (NoV) is recognized as the commonest cause of acute gastroenteritis among adults. Susceptibility to disease has been associated with histo-blood group antigens and secretor status; nonsecretors are almost completely resistant to disease.
Johan Nordgren, Elin Kindberg, Per-Eric Lindgren, Andreas Matussek, Lennart Svensson   +4 more
doaj   +1 more source

Genetic Manipulation of Human Intestinal Enteroids Demonstrates the Necessity of a Functional Fucosyltransferase 2 Gene for Secretor-Dependent Human Norovirus Infection

mBio, 2020
Human noroviruses (HuNoVs) are the leading cause of nonbacterial gastroenteritis worldwide. Histo-blood group antigen (HBGA) expression is an important susceptibility factor for HuNoV infection based on controlled human infection models and epidemiologic
Kei Haga, Khalil Ettayebi, Victoria R. Tenge, Umesh C. Karandikar, Miranda A. Lewis, Shih-Ching Lin, Frederick H. Neill, B. Vijayalakshmi Ayyar, Xi-Lei Zeng, Göran Larson, Sasirekha Ramani, Robert L. Atmar, Mary K. Estes   +12 more
doaj   +1 more source

Anti-Glycan Autoantibodies Induced by Helicobacter pylori as a Potential Risk Factor for Myocardial Infarction

Frontiers in Immunology, 2020
A number of epidemiological studies have evaluated the potential association between H. pylori and cardiovascular disease, but with contrasting results.
Riccardo Negrini, Vincenzo Villanacci, Claudio Poiesi, Antonella Savio   +3 more
doaj   +1 more source

Alternative Polyadenylation Contributes to Fibroblast Senescence in Pulmonary Fibrosis

Aging Cell, Volume 24, Issue 10, October 2025.
In aging or fibrotic fibroblasts, NUDT21 is downregulated, leading to alternative polyadenylation/3′ UTR shortening of STAT3 pathway genes, enhancing their protein expression and promoting STAT3 phosphorylation. Activated STAT3 signaling subsequently drives the expression and release of senescence‐associated secretory phenotype (SASP) factors, thereby ...
Jingjing Huang, Maria Jose Gacha‐Garay, Yu Wang, Scott D. Collum, Rene A. Girard, Hydia Puente, Seung‐Hee Yoo, Rahat Hussain, Jayeshkumar Patel, Manish Patel, Eric J. Wagner, Hari KrishnaYalamanchili, Harry Karmouty‐Quintana, Zheng Chen, Tingting Mills   +14 more
wiley   +1 more source

Detection of Gliadin‐Activated CD4+ T Cells Is a New Assay to Reveal Pathogenic Lymphocytes in Celiac Disease

Journal of Cellular and Molecular Medicine, Volume 29, Issue 20, October 2025.
ABSTRACT The diagnosis of celiac disease (CD) relies on the presence of serum antibodies against type 2‐tissue transglutaminase (tTG2) and endomysium, which in adult patients must be confirmed by assessing small intestinal mucosa damage through esophagogastroduodenoscopy.
Laura Pisapia, Marcella D'Ambrosio, Ilaria Mottola, Stefania Picascia, Domenico De Girolamo, Fabiana Castiglione, Nadia Tinto, Antonio Rispo, Carmen Gianfrani, Giovanna Del Pozzo   +9 more
wiley   +1 more source

Direct Blockade of the Norovirus Histo-Blood Group Antigen Binding Pocket by Nanobodies [PDF]

, 2023
Gargi Kher, Charles Sabin, Jennifer H. Lun, Jessica M. Devant, Kerstin Ruoff, A.D. Koromyslova, Mark von Itzstein, Marie Pancera, Grant S. Hansman   +8 more
openalex   +1 more source

Cloning, Expression, and Functional Characterization of FUT1, a Key Gene for Histo-Blood Group Antigens Synthesis in Crassostrea gigas. [PDF]

Curr Issues Mol Biol, 2023
Gui B, Yao L, Qu M, Zhang W, Li M, Jiang Y, Wang L.   +6 more
europepmc   +1 more source

Binding of Escherichia coli Does Not Protect Tulane Virus from Heat-Inactivation Regardless the Expression of HBGA-Like Molecules

Frontiers in Microbiology, 2017
Histo-blood group antigens (HBGAs) are considered as receptors/co-receptors for human norovirus (HuNoV). It has been reported that binding of HuNoV-derived virus-like particles (VLPs) to HBGA-like molecules-expressing bacteria increased the stability of ...
Qianqian Li, Qianqian Li, Dapeng Wang, David Yang, Lei Shan, Peng Tian   +5 more
doaj   +1 more source

ABO histo-blood group and risk of respiratory atopy in children: a review of published evidence

Pediatric Health, Medicine and Therapeutics, 2018
Samuel N Uwaezuoke,1 Joy N Eze,1 Adaeze C Ayuk,1 Ikenna K Ndu2 1Department of Paediatrics, University of Nigeria Teaching Hospital (UNTH), Ituku-Ozalla Enugu, Nigeria; 2Department of Paediatrics, Enugu State University Teaching Hospital, Enugu, Nigeria ...
Uwaezuoke SN, Eze JN, Ayuk AC, Ndu IK
doaj  

Functional and structural characterization of Norovirus GII.6 in recognizing histo-blood group antigens. [PDF]

Virol Sin, 2023
Cong X, Li HB, Sun XM, Qi JX, Zhang Q, Duan ZJ, Xu Y, Liu WL.   +7 more
europepmc   +1 more source