Results 11 to 20 of about 132 (71)

A Novel Atypical PKC-Iota Inhibitor, Echinochrome A, Enhances Cardiomyocyte Differentiation from Mouse Embryonic Stem Cells [PDF]

Marine Drugs, 2018
Echinochrome A (EchA) is a marine bioproduct extracted from sea urchins having antioxidant, antimicrobial, anti-inflammatory, and chelating effects, and is the active component of the clinical drug histochrome.
Hyoung Kyu Kim, Sung Woo Cho, Hye Jin Heo, Seung Hun Jeong, Min Kim, Kyung Soo Ko, Byoung Doo Rhee, Natalia P. Mishchenko, Elena A. Vasileva, Sergey A. Fedoreyev, Valentin A. Stonik, Jin Han   +11 more
doaj   +2 more sources

Echinochrome A Reduces Colitis in Mice and Induces In Vitro Generation of Regulatory Immune Cells [PDF]

Marine Drugs, 2019
Echinochrome A (Ech A), a natural pigment extracted from sea urchins, is the active ingredient of a marine-derived pharmaceutical called ‘histochrome’.
Su-Jeong Oh, Yoojin Seo, Ji-Su Ahn, Ye Young Shin, Ji Won Yang, Hyoung Kyu Kim, Jin Han, Natalia P. Mishchenko, Sergey A. Fedoreyev, Valentin A. Stonik, Hyung-Sik Kim   +10 more
doaj   +2 more sources

Liposomal Form of the Echinochrome-Carrageenan Complex [PDF]

Marine Drugs, 2018
Inclusion of drugs in liposomes offers the potential for localized and sustained delivery to mucosal surfaces. The inclusion of the carrageenan matrix with echinochrome A ((Ech)—the active substance of the drug Histochrome) in liposomes was studied.
Irina M. Yermak, Vladimir I. Gorbach, Valery P. Glazunov, Anna O. Kravchenko, Natalya P. Mishchenko, Evgeniya A. Pimenova, Viktoria N. Davydova   +6 more
doaj   +2 more sources

Effects of Carrageenans on Biological Properties of Echinochrome [PDF]

Marine Drugs, 2018
Sea urchin pigment echinochrome A (Ech), a water-insoluble compound, is the active substance in the cardioprotective and antioxidant drug Histochrome® (PIBOC FEB RAS, Moscow, Russia).
Ekaterina V. Sokolova, Natalia I. Menzorova, Victoria N. Davydova, Alexandra S. Kuz’mich, Anna O. Kravchenko, Natalya P. Mishchenko, Irina M. Yermak   +6 more
doaj   +2 more sources

Echinochrome A Protects Mitochondrial Function in Cardiomyocytes against Cardiotoxic Drugs

Marine Drugs, 2014
Echinochrome A (Ech A) is a naphthoquinoid pigment from sea urchins that possesses antioxidant, antimicrobial, anti-inflammatory and chelating abilities.
Seung Hun Jeong, Hyoung Kyu Kim, In-Sung Song, Seon Joong Lee, Kyung Soo Ko, Byoung Doo Rhee, Nari Kim, Natalia P. Mishchenko, Sergey A. Fedoryev, Valentin A. Stonik, Jin Han   +10 more
doaj   +1 more source

Echinochrome A inhibits epithelial–mesenchymal transition and induces cell death mediated by DNA damage in human triple-negative breast cancer cells

Journal of Functional Foods
Echinochrome A (Ech A), a marine-derived compound from Scaphechinus mirabilis, is known for its potent antioxidant activity. Its pharmacological derivative, Histochrome, is used to treat ischemia and cardiovascular disorders.
Soon Yong Park, Mi-So Jeong, Cong So Tran, Jinyoung Lee, Da-Young Eum, Seyeon Jung, Elena A. Vasileva, Seoung Rak Lee, Hyoung Kyu Kim, Natalia P. Mishchenko, Jin Han, Yoo Jin Choi, Si Ho Choi, Hwayoung Yun, Kyu Heo   +14 more
doaj   +1 more source

Quinoid Pigments of Sea Urchins Scaphechinus mirabilis and Strongylocentrotus intermedius: Biological Activity and Potential Applications. [PDF]

Mar Drugs, 2022
Ageenko NV, Kiselev KV, Odintsova NA.
europepmc   +1 more source

Multiple Effects of Echinochrome A on Selected Ion Channels Implicated in Skin Physiology. [PDF]

Mar Drugs, 2023
Kim SE, Chung EDS, Vasileva EA, Mishchenko NP, Fedoreyev SA, Stonik VA, Kim HK, Nam JH, Kim SJ.   +8 more
europepmc   +1 more source

Cardiomyocyte Damage: Ferroptosis Relation to Ischemia-Reperfusion Injury and Future Treatment Options. [PDF]

Int J Mol Sci, 2023
Laukaitiene J, Gujyte G, Kadusevicius E.
europepmc   +1 more source

Effect of Echinochrome A on Submandibular Gland Dysfunction in Ovariectomized Rats. [PDF]

Mar Drugs, 2022
Kim JM, Shin SC, Cheon YI, Kim HS, Park GC, Kim HK, Han J, Seol JE, Vasileva EA, Mishchenko NP, Fedoreyev SA, Stonik VA, Lee BJ.   +12 more
europepmc   +1 more source