Effects of Carrageenans on Biological Properties of Echinochrome [PDF]
Marine Drugs, 2018 Sea urchin pigment echinochrome A (Ech), a water-insoluble compound, is the active substance in the cardioprotective and antioxidant drug Histochrome® (PIBOC FEB RAS, Moscow, Russia).
Ekaterina V. Sokolova +6 more
doaj +4 more sources
Echinochrome A Reduces Colitis in Mice and Induces In Vitro Generation of Regulatory Immune Cells [PDF]
Marine Drugs, 2019 Echinochrome A (Ech A), a natural pigment extracted from sea urchins, is the active ingredient of a marine-derived pharmaceutical called ‘histochrome’.
Su-Jeong Oh +10 more
doaj +4 more sources
Liposomal Form of the Echinochrome-Carrageenan Complex [PDF]
Marine Drugs, 2018 Inclusion of drugs in liposomes offers the potential for localized and sustained delivery to mucosal surfaces. The inclusion of the carrageenan matrix with echinochrome A ((Ech)—the active substance of the drug Histochrome) in liposomes was studied.
Irina M. Yermak +6 more
doaj +4 more sources
Echinochrome A Protects Mitochondrial Function in Cardiomyocytes against Cardiotoxic Drugs [PDF]
Marine Drugs, 2014 Echinochrome A (Ech A) is a naphthoquinoid pigment from sea urchins that possesses antioxidant, antimicrobial, anti-inflammatory and chelating abilities.
Seung Hun Jeong +10 more
doaj +2 more sources
Russian Pediatric Ophthalmology, 2013 This paper is designed to report the results of the application of histochrome for the treatment of the children presenting with «pre-plus» disease and concomitant active retinopathy of prematurity. The preparation was administered intramuscularly in the form of a 0.02% solution.
L A Katargina
exaly +2 more sources
Marine Polyhydroxynaphthoquinone, Echinochrome A: Prevention of Atherosclerotic Inflammation and Probable Molecular Targets. [PDF]
J Clin Med, 2020 The effect of low doses of echinochrome A (EchA), a natural polyhydroxy-1,4-naphthoquinone pigment from the sea urchin Scaphechinus mirabilis, has been studied in clinical trials, when it was used as an active substance of the drug Histochrome® and ...
Artyukov AA +6 more
europepmc +2 more sources
The effects of preparation “histochrom” in biochemical parameters of blood for patients with cardiopathologies [PDF]
Biomeditsinskaya Khimiya, 2014 The effects of the small doses of the preparation Gistochrome, containing natural polyhydroxynaphtoquinoine echinochrom A from flat sea urchin Scaphechinus mirabilis , on blood biochemical parameters have been studied in patients with cardiovascular diseases.
A V, Tsybulskiĭ +7 more
openaire +2 more sources
Hystochrome influence on physical endurance of rats
Бюллетень сибирской медицины, 2016 Introduction. Domestic antioxidant drugs series «Gistohrom®» are based on the marine natural compounds echinochrome A. «Gistohrom®»activates cell energy metabolism and protein synthesis, increases the body’s endurance under extreme physical exertion. The
O. S. Talalaeva +2 more
doaj +1 more source
The cellular and molecular mechanisms providing therapeutic efficiency of gistokhrom [PDF]
, 2017 The review presents the screening of the therapeutic effects of the Russia drug “Histochrome”, active substance of which is quinoid pigment marine - echinochrome A (2,3,5,6,8-pentahydroxy-7-ethyl-1,4-naphthoquinone). Assessing the pharmacological aspects
Yakov F Zverev +2 more
core +1 more source
DOSE-DEPENDENDENT HISTOCHROME EFFECTS OF KIDNEY IN RATS
Nephrology (Saint-Petersburg), 2017 THE AIM.Histochrome is a native antioxidant drug isolated from natural sourse. The study of pharmacological activity of histochrome showed a wide spectrum of dose-range action. The aim of this study was to investigate the renal effects changes when administered various doses of histochrome in rats.MATERIALS AND METHODS.The study was conducted on ...
O. S. Talalaeva +3 more
openaire +2 more sources