Results 261 to 270 of about 285,083 (334)

Molecular evolutionary genetics analysis of major histocompatibility complex class I, II and III genes in ruminants and monogastrics

, 2019
O.A. Bolatito, C. O. N. Ikeobi, O.M. Onagbesan   +2 more
openalex   +2 more sources

Mesenchymal stromal cell therapy for rheumatoid arthritis: Long‐term efficacy, safety, and mechanistic insights

Rheumatology &Autoimmunity, EarlyView.
Graphical abstract summarizing the multifactorial pathogenesis of rheumatoid arthritis (RA) and the therapeutic potential of mesenchymal stromal cell (MSC) therapy. MSCs provide promising benefits through their immunomodulatory properties, low immunogenicity, ability to promote tissue repair, and multi‐lineage differentiation, presenting a potential ...
Yingjia Chen, Ruiyu Gao, Xing Guo, Genhong Yao, Xiaojun Tang, Yile E. Liu, Lingyun Sun   +6 more
wiley   +1 more source

T-cell receptor insights: Determinants of Major Histocompatibility Complex class I versus class II recognition. [PDF]

Protein Sci
De Almeida Mendes M, Chihab L, Nilsson JB, Scheffer L, Nielsen M, Peters B.   +5 more
europepmc   +1 more source

Genetic and cytological aspects of histocompatibility in ascidians

, 1992
Armando Sabbadin, Giovanna Zaniolo, Loriano Ballarin   +2 more
openalex   +2 more sources

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

NeoGuider: neoepitope prediction using advanced feature engineering. [PDF]

Genome Med
Zhao X, Wei L, Xie Z, Zhang X.
europepmc   +1 more source

Organelle Sorting and Proteomic Analysis to Identify Proteins Involved in the Uptake and Intracellular Trafficking of Nanoparticles

Small Methods, EarlyView.
A new method to identify proteins involved in the uptake and intracellular trafficking of nanoparticles is presented. After nanoparticle uptake, cells are lysed and the organelles with nanoparticles are purified using fluorescence assisted cell sorting. Next, their composition is determined by proteomic analysis.
Hector Garcia Romeu, Anna Salvati
wiley   +1 more source

Reply. [PDF]

ACR Open Rheumatol
Khoo T, Saxon S, Koszyca B, Gutschmidt B, Limaye V.   +4 more
europepmc   +1 more source

Identification of genetically predicted protein biomarkers and drug targets for prostate cancer via Mendelian randomization

VIEW, EarlyView.
Prostate cancer, a leading cause of cancer in men globally, urgently requires improved diagnostic and treatment strategies. This study analyzed large genetic datasets and identified five key proteins (THBD, DST, IFI27L2, OSBPL10, PPP1R14A) that either increase or decrease cancer risk, while also exploring their roles in immune response and potential ...
Maoping Cai, Tianming Peng, Zhiyue Xie, Chuqian Zhen, Chen Yao, Nan Peng, Qianyi Li, Yuzhong Yu, Jiming Bao, Xian‐Lu Song, Mingkun Chen, Shan‐Chao Zhao   +11 more
wiley   +1 more source

Multi-omic profiling provides insights into the heterogeneity, microenvironmental features, and biomarker landscape of small-cell lung cancer. [PDF]

Mol Cancer
Xie M, Vuko M, Saran S, Liu S, Chambers AG, Baakza H, Angell HK, Ng F, Gay CM, Cardnell RJ, Segerer FJ, Andoni A, Rodriguez-Canales J, Waring PM, Schick M, Barrett JC, Byers LA, Fabbri G.   +17 more
europepmc   +1 more source