Results 271 to 280 of about 211,384 (368)

Promising candidate drug target genes for repurposing in cervical cancer: A bioinformatics-based approach. [PDF]

open access: yesNarra J
Pratiwi N   +9 more
europepmc   +1 more source

Hetrombopag: A promising thrombopoietin receptor agonist for the treatment of primary and secondary immune thrombocytopenia

open access: yesRheumatology &Autoimmunity, EarlyView.
This review seeks to provide a thorough synthesis of the existing literature on the role of thrombopoietin receptor agonists in the treatment of primary and secondary immune thrombocytopenia, with particular emphasis on the compound Hetrombopag. Abstract Immune thrombocytopenia (ITP) is a rare autoimmune disorder characterized by a platelet count below
Jiaqi Hu   +8 more
wiley   +1 more source

Omega-3 EPA Supplementation Shapes the Gut Microbiota Composition and Reduces Major Histocompatibility Complex Class II in Aged Wild-Type and APP/PS1 Alzheimer's Mice: A Pilot Experimental Study. [PDF]

open access: yesNutrients
Altendorfer B   +12 more
europepmc   +1 more source

Neurodegeneration and Demyelination in the Multiple Sclerosis Spinal Cord: Clinical, Pathological, and 7T MRI Perspectives. [PDF]

open access: yesNeurology
Mahajan KR   +7 more
europepmc   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

open access: yesSmall, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa   +4 more
wiley   +1 more source

Understanding "Null Allele" in Renal Transplantation. [PDF]

open access: yesTransplant Direct
Sulaiman S   +5 more
europepmc   +1 more source

Human Dermal Microvascular Arterial and Venous Blood Endothelial Cells and Their Use in Bioengineered Dermo‐Epidermal Skin Substitutes

open access: yesSmall Methods, EarlyView.
This study unveils a pioneering approach to bioengineering of human skin substitutes with distinct arterial and venous capillaries. Combining single‐cell transcriptomics and 3D hydrogel models, this work reveals unique endothelial marker dynamics in fetal and juvenile skin.
Dominic Rütsche   +9 more
wiley   +1 more source

Predicting reverse-bound peptide conformations in MHC Class II with PANDORA. [PDF]

open access: yesFront Immunol
Rademaker DT   +5 more
europepmc   +1 more source

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