Results 271 to 280 of about 285,083 (334)

Integrative Analysis of Plasma Proteome and Genome Reveals Novel Drug Targets for Chronic Rhinosinusitis and Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) and nasal polyps (NP) are chronic inflammatory conditions with unsatisfactory treatment outcomes due to frequent recurrence of refractory disease. Identifying new therapeutic targets is essential. Methods We conducted a proteome‐wide Mendelian randomization (MR) analysis by integrating genome‐wide ...
En Zhou, Shi Luo, Yu Xiao, Bin Liu, Xu‐Ping Xiao   +4 more
wiley   +1 more source

Role of autophagy in rejection after solid organ transplantation: A systematic review of the literature. [PDF]

World J Transplant
Jiang SM, Li XJ, Wang ZL, Chen ZW, Liu ZL, Li Q, Chen XL.   +6 more
europepmc   +1 more source

Milestones in Transplantation: The Story so Far [PDF]

, 2001
Starzl, TE
core  

Plasma Proteomics Analysis Identifying IGFBP2 as a Potential Diagnostic Biomarker for Laryngeal Squamous Cell Carcinoma

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Objective Currently, there are no blood biomarkers available for the early diagnosis of laryngeal squamous cell carcinoma (LSCC). The objective of this study was to search for potential plasma biomarkers for the diagnosis of LSCC. Methods Plasma samples were taken from patients with LSCC and healthy controls for proteomic analysis.
Shuang Teng, Ling‐Mei Qu, Jun‐Jie Liu, Yu‐Shan Li, Zi‐Qi Chen, Shuo Liu, Zhao‐Nan Xu, Meng Jin, Qiu‐Ying Li, Qin Wu, Hong‐Tian Yi, Xian‐Ji Shen, Bing‐Rui Yan, Ya‐Nan Sun   +13 more
wiley   +1 more source

Exosomes in Autoimmunity: Mediators of Autoantigen Presentation and Targets for Therapeutic Intervention in Autoimmune Diseases. [PDF]

J Clin Immunol
Almohaimeed HM, Almars AI, Tounsi WA, Mohammedsaleh ZM, Panigrahi R, Singh I, Singh S, Dhara B, Uti DE.   +8 more
europepmc   +1 more source

Microhaplotype Methods Enable Relationship Inference in a Bottlenecked Mammalian Species

Animal Conservation, EarlyView.
Northern elephant seals (Mirounga angustirostris) are among the most genetically depauperate mammals in the world. A near‐total population bottleneck in the 19th century, coupled with the breeding system of extreme polygyny, has challenged efforts to estimate individual reproductive success with genetic methods.
Keith M. Hernandez, Anthony J. Clemento, Juliette E. Linossier, Daniel E. Crocker, Daniel P. Costa, Colleen Reichmuth, John Carlos Garza   +6 more
wiley   +1 more source

Association of MHC class II β domain polymorphism in channel catfish (Ictalurus punctatus) with natural infection by Ligictaluridus floridanus. [PDF]

Parasitol Res
Roldán GMG, Bracamonte GMP, González FB, Alfaro IOM, Di Carlo Quiroz Velásquez J, De La Rosa-Reyna XF.   +5 more
europepmc   +1 more source

Burrow Persistence and Spatial Distribution of Federally and State‐Protected Gopher Tortoise (Gopherus polyphemus) Populations in Southwest Alabama

Animal Conservation, EarlyView.
The gopher tortoise (Gopherus polyphemus), a keystone species and ecosystem engineer, has declined by ~80% over the past century due to primarily habitat loss. In a 28‐year resurvey of federally protected Mobile County and state‐protected Baldwin County, we found tortoise populations persisted at ~59% and ~31% of sites, respectively, with significant ...
Robin B. Lloyd Jr., Jeremiah A. Henning, Steven R. Schultze, David H. Nelson, Adam D. Chupp   +4 more
wiley   +1 more source

Case Report: A novel CIITA mutation causing MHC class II deficiency: first reported case in Morocco. [PDF]

Front Immunol
Kattra AB, Ailal F, Benhsaien I, Fahi M, Drissi Bourhanbour A, Elamine A, Aadam Z, Errami A, Bousfiha AA, El Bakkouri J.   +9 more
europepmc   +1 more source

The Therapeutic Potential of Farm Dust Extracts in a Mouse Model of Eosinophilic Inflammation

Allergy, EarlyView.
Farm dust extract (FDE) treatment reduces airway eosinophilia, mucus overproduction, and MHC‐II expression on DCs, limiting antigen presentation and Th2 inflammation. It increases PD‐L1 on DCs, promoting T cell deactivation. Additionally, FDE enhances Tregs and upregulates CTLA‐4, reinforcing suppression.
Rabia Ülkü Korkmaz, Jimmy Omony, Xiaomei Tan, Markus Klotz, Guilherme Dragunas, Sirui Chen, Soni Shankhwar, Zeynep Ertüz, Christoph Müller, Mohab Ragab, Aicha Jeridi, Romina Augustin, Janna Nawroth, Theodore S. Kapellos, Bettina Rankl, Ali Önder Yildirim, Erika von Mutius   +16 more
wiley   +1 more source