Results 51 to 60 of about 197,788 (257)

Identification of a Colonial Chordate Histocompatibility Gene [PDF]

, 2013
Histocompatibility is the basis by which multicellular organisms of the same species distinguish self from nonself. Relatively little is known about the mechanisms underlying histocompatibility reactions in lower organisms.
Ayelet Voskoboynik, Winston Koh, Passarelli, Benedetto, Mantalas, Gary L, Karla J. Palmeri, Koh, Winston, Weissman, Irving L, Norma F. Neff, Newman, Aaron M, Aaron M. Newman, Dimov, Ivan K, H. Christina Fan, Voskoboynik, Ayelet, Neff, Norma F, Keasar, Chen, Irving L. Weissman, Penland, Lolita, Stephen R. Quake, Sahoo, Debashis, Ishizuka, Katherine J, Katherine J. Ishizuka, Lolita Penland, Palmeri, Karla J, Debashis Sahoo, Dmitry Pushkarev, Quake, Stephen R, Gary L. Mantalas, Daniel M. Corey, Rahul Sinha, Fan, H Christina, Benedetto Passarelli, Pushkarev, Dmitry, Sinha, Rahul, Ivan K. Dimov, Chen Keasar, Corey, Daniel M   +35 more
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Definitions of histocompatibility typing terms

, 2011
Histocompatibility testing for stem cell and solid organ transplantation has become increasingly complex as newly discovered HLA alleles are described.
Wagenknecht, Dawn R, Cynthia Taves, Carolyn Katovich Hurley, Fernandez-Vina, Marcelo, Heslop, Helen, Noreen, Harriet, Helen Heslop, Marcelo Fernandez-Vina, Eduardo Nunes, Dawn R. Wagenknecht, Sacchi, Nicoletta, Eisenbrey, A Bradley, Harriet Noreen, Kay Poulton, Nunes, Eduardo, Gottfried Fischer, Nicoletta Sacchi, Taves, Cynthia, Fischer, Gottfried, Hurley, Carolyn Katovich, Wacker, Kara, Kara Wacker, Poulton, Kay, A. Bradley Eisenbrey   +23 more
core   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

HLA-DR/DQ eplet mismatch predicts de novo donor-specific antibody development in multi-ethnic Southeast Asian kidney transplant recipients on different immunosuppression regimens

Frontiers in Genetics
Eplet mismatch has been recognized as a more precise strategy for determining HLA compatibility by analyzing donor-recipient HLA differences at the molecular level.
Emmett Tsz Yeung Wong, Emmett Tsz Yeung Wong, Emmett Tsz Yeung Wong, Denise Pochinco, Anantharaman Vathsala, Anantharaman Vathsala, Wee Kun Koh, Amy Lim, Hersharan Kaur Sran, Hersharan Kaur Sran, Matthew Ross D’Costa, Zi Yun Chang, Peter W. Nickerson, Peter W. Nickerson, Peter W. Nickerson, Chris Wiebe, Chris Wiebe, Chris Wiebe   +17 more
doaj   +1 more source

In silico analysis of minor histocompatibility antigens.

, 2016
In silico analysis of minor histocompatibility antigens.
Marieke Griffioen (119817), Dyantha I. van der Lee (3115227), Margot J. Pont (3115230), J. H. Frederik Falkenburg (210432)   +3 more
core   +1 more source

From Adult to Adolescent: Alignment in Clinical Trials and Outcomes in Axial Spondyloarthritis

Arthritis Care &Research, EarlyView.
Spondyloarthritis (SpA) is a group of chronic inflammatory diseases encompassing axial and peripheral forms, with up to 20% of patients developing symptoms before age 16. Despite this substantial pediatric burden, treatment options for juvenile‐onset SpA (JSpA), particularly those with axial disease (axJSpA), remain limited.
Pamela F. Weiss, Judith A. Smith, Robert A. Colbert, Erin Treemarcki, Michael H. Weisman, Walter P. Maksymowych, Hermine I. Brunner, for the Childhood Arthritis and Rheumatology Research Alliance, Spondyloarthritis Research and Treatment Network, and Pediatric Rheumatology Collaborative Study Group Advisory Council   +9 more
wiley   +1 more source

Transcriptomic Profiling of the Allorecognition Response to Grafting in the Demosponge Amphimedon queenslandica

Marine Drugs, 2017
Sponges, despite their simple body plan, discriminate between self and nonself with remarkable specificity. Sponge grafting experiments simulate the effects of natural self or nonself contact under laboratory conditions.
Laura F. Grice, Bernard M. Degnan
doaj   +1 more source

COVID‐19 systematic screening of asymptomatic haematopoietic stem cell donors: Less if often more

eJHaem, 2022
From COVID pandemic spread until now, many HSCT unrelated donor registries recommend as a precaution a systematic COVID‐19 testing for all donors during the precollection time. Literature is quite poor to support this systematic attitude.
Lucie Blandin, Elise Tolmer, Eric Hermet, Aurélie Ravinet, Amélie Brebion, Richard Lemal, Paul Rouzaire   +6 more
doaj   +1 more source

Topically Delivered Treg‐Attracting Microparticle‐Hydrogel Composites Recruit Regulatory T Cells and Limit Cardiac Injury After Severe Ischemia

Advanced Healthcare Materials, EarlyView.
CCL22‐releasing PLGA microparticles (MP) suspended in topically applied hydrogels (HEART) establish a sustained chemokine gradient at the injured myocardium. HEART recruits CCR4+ regulatory T cells, reduces infarct size and graft fibrosis, and improves cardiac function.
Matthew A. Borrelli, Alexis T. Reese, Jordan J. P. Warunek, Betsy Ann Varghese, Canxing Lin, Jeffery J. Baust, Brenda McMahon, Steven R. Little, Hēth R. Turnquist   +8 more
wiley   +1 more source